フォロー
Larisa V. Kovtonyuk
Larisa V. Kovtonyuk
University Hospital and University of Zurich PostDoc
確認したメール アドレス: usz.ch
タイトル
引用先
引用先
Chronic interleukin-1 exposure drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal
EM Pietras, C Mirantes-Barbeito, S Fong, D Loeffler, LV Kovtonyuk, ...
Nature cell biology 18 (6), 607-618, 2016
5822016
Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment
LV Kovtonyuk, K Fritsch, X Feng, MG Manz, H Takizawa
Frontiers in immunology 7, 502, 2016
3332016
Microbiota-derived compounds drive steady-state granulopoiesis via MyD88/TICAM signaling
ML Balmer, CM Schürch, Y Saito, MB Geuking, H Li, M Cuenca, ...
The Journal of Immunology 193 (10), 5273-5283, 2014
2552014
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell stem cell 21 (2), 225-240. e5, 2017
2442017
IL-1 mediates microbiome-induced inflammaging of hematopoietic stem cells in mice
LV Kovtonyuk, F Caiado, S Garcia-Martin, EM Manz, P Helbling, ...
Blood, The Journal of the American Society of Hematology 139 (1), 44-58, 2022
572022
Enhanced thrombopoietin but not G-CSF receptor stimulation induces self-renewing hematopoietic stem cell divisions in vivo
LV Kovtonyuk, MG Manz, H Takizawa
Blood, The Journal of the American Society of Hematology 127 (25), 3175-3179, 2016
562016
inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice
JM Ellegast, PJ Rauch, LV Kovtonyuk, R Müller, U Wagner, Y Saito, ...
Blood, The Journal of the American Society of Hematology 128 (17), 2130-2134, 2016
452016
Aging drives Tet2+/− clonal hematopoiesis via IL-1 signaling
F Caiado, LV Kovtonyuk, NG Gonullu, J Fullin, S Boettcher, MG Manz
Blood, The Journal of the American Society of Hematology 141 (8), 886-903, 2023
352023
Immunotherapy of hepatocellular carcinoma with small double-stranded RNA
TO Kabilova, LV Kovtonyuk, EV Zonov, EI Ryabchikova, NA Popova, ...
BMC cancer 14, 1-11, 2014
332014
Fas (CD 95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance
S Wueest, R Mueller, M Blüher, F Item, ASH Chin, MSF Wiedemann, ...
EMBO molecular medicine 6 (1), 43-56, 2014
292014
Chronic viral infections persistently alter marrow stroma and impair hematopoietic stem cell fitness
S Isringhausen, YV Mun, L Kovtonyuk, NJ Kräutler, U Suessbier, ...
Journal of Experimental Medicine 218 (12), e20192070, 2021
262021
Inflamm-aging of hematopoiesis, hematopoietic stem cells, and the bone marrow microenvironment. Front Immunol. 2016; 7: 502
LV Kovtonyuk, K Fritsch, X Feng, MG Manz, H Takizawa
This comprehensive review present evidence supporting the concept of …, 2016
182016
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell Stem Cell 27 (1), 177, 2020
122020
TP53 mutations confer resistance to hypomethylating agents and BCL-2 inhibition in myeloid neoplasms
RR Schimmer, LV Kovtonyuk, N Klemm, J Fullin, SM Stolz, J Mueller, ...
Blood advances 6 (11), 3201-3206, 2022
92022
CXCL12-abundant reticular cells are the major source of IL-6 upon LPS stimulation and thereby regulate hematopoiesis
RC Gerosa, S Boettcher, LV Kovtonyuk, A Hausmann, WD Hardt, ...
Blood advances 5 (23), 5002-5015, 2021
92021
A single metabolite which modulates lipid metabolism alters hematopoietic stem/progenitor cell behavior and promotes lymphoid reconstitution
S Giger, LV Kovtonyuk, SG Utz, M Ramosaj, WJ Kovacs, E Schmid, ...
Stem cell reports 15 (3), 566-576, 2020
92020
Humanised mouse models for haematopoiesis and infectious diseases
V Lysenko, D McHugh, L Behrmann, MA Rochat, CM Wilk, LV Kovtonyuk, ...
Swiss medical weekly 147, w14516, 2017
92017
Hematopoietic stem cells increase quiescence during aging
LV Kovtonyuk, P Ashcroft, G Spaltro, NR Tata, RC Skoda, S Bonhoeffer, ...
Blood 134, 2484, 2019
52019
Microbial metabolites and immunotherapy: Basic rationale and clinical indications
LV Kovtonyuk, KD McCoy
Seminars in Immunology 67, 101755, 2023
42023
Clonal dynamics after allogeneic haematopoietic cell transplantation using genome-wide somatic mutations
P Campbell, MS Chapman, M Wilk, S Boettcher, E Mitchell, K Dawson, ...
22023
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