Appropriately differentiated ARPE-19 cells regain phenotype and gene expression profiles similar to those of native RPE cells W Samuel, C Jaworski, OA Postnikova, RK Kutty, T Duncan, LX Tan, ... Molecular vision 23, 60, 2017 | 167 | 2017 |
Cholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epithelium KA Toops, LX Tan, Z Jiang, RA Radu, A Lakkaraju Molecular biology of the cell 26 (1), 1-14, 2015 | 93 | 2015 |
A detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayers KA Toops, LX Tan, A Lakkaraju Experimental eye research 124, 74, 2014 | 67 | 2014 |
Aberrant early endosome biogenesis mediates complement activation in the retinal pigment epithelium in models of macular degeneration G Kaur, LX Tan, G Rathnasamy, N La Cunza, CJ Germer, KA Toops, ... Proceedings of the National Academy of Sciences 115 (36), 9014-9019, 2018 | 57 | 2018 |
Protective responses to sublytic complement in the retinal pigment epithelium LX Tan, KA Toops, A Lakkaraju Proceedings of the National Academy of Sciences 113 (31), 8789-8794, 2016 | 54 | 2016 |
Environmental and genetic factors regulating localization of the plant plasma membrane H+-ATPase M Haruta, LX Tan, DB Bushey, SJ Swanson, MR Sussman Plant physiology 176 (1), 364-377, 2018 | 38 | 2018 |
Apolipoprotein E isoforms and AMD KA Toops, LX Tan, A Lakkaraju Retinal Degenerative Diseases, 3-9, 2016 | 37 | 2016 |
Use of inhibitors of acid sphingomyelinase to treat acquired and inherited retinal degenerations A Lakkaraju, KA Toops, LX Tan US Patent App. 10/124,008, 2018 | 27* | 2018 |
Use of inhibitors of acid sphingomyelinase to treat acquired and inherited retinal degenerations A Lakkaraju, KA Toops, LX Tan US Patent App. 14/746,221, 2018 | 2 | 2018 |
Live-cell imaging of mitochondrial dynamics in the retinal pigment epithelium G Rathnasamy, LX Tan, A Lakkaraju Investigative Ophthalmology & Visual Science 59 (9), 4028-4028, 2018 | 2 | 2018 |
Use of Inhibitors of Acid Sphingomyelinase to Treat Acquired and Inherited Retinal Degenerations A Lakkaraju, KA Toops, LX Tan US Patent App. 14/746,221, 2015 | 2 | 2015 |
Differential regulation of organelle dynamics by tubulin acetylation in polarized epithelia. KA Toops, L Tan, A Lakkaraju MOLECULAR BIOLOGY OF THE CELL 25, 2014 | 1 | 2014 |
Aberrant endosome dynamics in the retinal pigment epithelium promote complement C3 activation in models of macular degeneration LX Tan, G Kaur, G Rathnasamy, N LaCunza, A Lakkaraju Investigative Ophthalmology & Visual Science 59 (9), 3992-3992, 2018 | | 2018 |
Modulation of mitochondrial respiration in hPSC-RPE D Sinha, G Rathnasamy, KA Toops, MM Wilson, R Valiauga, LX Tan, ... Investigative Ophthalmology & Visual Science 58 (8), 3025-3025, 2017 | | 2017 |
Polarized secretion of pro-inflammatory exosomes by the retinal pigment epithelium is selectively regulated by vitamin A dimers and membrane cholesterol A Lakkaraju, C Germer, LX Tan, G Kaur Investigative Ophthalmology & Visual Science 58 (8), 1049-1049, 2017 | | 2017 |
Increased biogenesis and fusion of early endosomes promotes complement activation in the retinal pigment epithelium. L Tan, G Kaur, KA Toops, N La Cunza, G Rathnasamy, A Lakkaraju MOLECULAR BIOLOGY OF THE CELL 28, 2017 | | 2017 |
Protective mechanisms against sub-lytic complement attack in the retinal pigment epithelium LX Tan, KA Toops, A Lakkaraju Investigative Ophthalmology & Visual Science 57 (12), 5783-5783, 2016 | | 2016 |
Retinal pigment epithelium organelle biogenesis and trafficking in models of macular degeneration KA Toops, LX Tan, A Lakkaraju Investigative Ophthalmology & Visual Science 57 (12), 2016 | | 2016 |
Altered lysosome positioning perturbs critical homeostatic functions in the retinal pigment epithelium L Tan, KA Toops, A Lakkaraju MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
FDA-approved acid sphingomyelinase inhibitors stimulate cellular clearance and reduce inflammation in the retinal pigment epithelium A Lakkaraju, KA Toops, LX Tan Investigative Ophthalmology & Visual Science 56 (7), 5458-5458, 2015 | | 2015 |