Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles HB Schmidt, D Görlich Trends in biochemical sciences 41 (1), 46-61, 2016 | 408 | 2016 |
A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ... The EMBO Journal, e97452, 2018 | 326 | 2018 |
Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity HB Schmidt, D Görlich eLife 4, e04251, 2015 | 297 | 2015 |
TDP-43 α-helical structure tunes liquid–liquid phase separation and function AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ... Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020 | 268 | 2020 |
TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A XR Ma, M Prudencio, Y Koike, SC Vatsavayai, G Kim, F Harbinski, ... Nature, 1-7, 2022 | 237 | 2022 |
Amyloid-like interactions within nucleoporin FG hydrogels C Ader, S Frey, W Maas, HB Schmidt, D Görlich, M Baldus Proceedings of the National Academy of Sciences 107 (14), 6281, 2010 | 196 | 2010 |
In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes HB Schmidt, R Rohatgi Cell Reports 16 (5), 1228-1236, 2016 | 164 | 2016 |
Phase separation-deficient TDP43 remains functional in splicing HB Schmidt, A Barreau, R Rohatgi Nature communications 10 (1), 4890, 2019 | 126 | 2019 |
Intrinsically disordered protein biosensor tracks the physical-chemical effects of osmotic stress on cells CL Cuevas-Velazquez, T Vellosillo, K Guadalupe, HB Schmidt, F Yu, ... Nature communications 12 (1), 5438, 2021 | 62 | 2021 |
Oxaliplatin disrupts nucleolar function through biophysical disintegration HB Schmidt, ZA Jaafar, BE Wulff, JJ Rodencal, K Hong, MO Aziz-Zanjani, ... Cell Reports 41 (6), 111629, 2022 | 20* | 2022 |
Aberrant Phase Separation of FUS Leads to Lysosome Sequestering and Acidification F Trnka, C Hoffmann, H Wang, R Sansevrino, B Rankovic, BR Rost, ... Frontiers in Cell and Developmental Biology 9, 2021 | 10 | 2021 |
Aberrant phase separation is a common killing strategy of positively charged peptides in biology and human disease S Boeynaems, XR Ma, V Yeong, GM Ginell, JH Chen, JA Blum, ... bioRxiv, 2023.03. 09.531820, 2023 | 7 | 2023 |
High-throughput Flow Cytometry Assay to Investigate TDP43 Splicing Function HB Schmidt, R Rohatgi Bio-protocol 10 (9), e3594, 2020 | 2 | 2020 |
Direct ionic stress sensing and mitigation by the transcription factor NFAT5 CB Khandwala, P Sarkar, HB Schmidt, M Ma, M Kinnebrew, GV Pusapati, ... bioRxiv, 2023.09. 23.559074, 2023 | 1 | 2023 |
Evolutionary Conserved Features of FG Repeats that Allow the Formation of Hydrogel-based Permeability Barriers with NPC-like Properties HB Schmidt Cuvillier, 2013 | | 2013 |