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Mark T. Gladwin
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Updated clinical classification of pulmonary hypertension
G Simonneau, IM Robbins, M Beghetti, RN Channick, M Delcroix, ...
Journal of the American college of cardiology 54 (1_Supplement_S), S43-S54, 2009
58832009
The nitrate–nitrite–nitric oxide pathway in physiology and therapeutics
JO Lundberg, E Weitzberg, MT Gladwin
Nature reviews Drug discovery 7 (2), 156-167, 2008
25792008
Sickle-cell disease
DC Rees, TN Williams, MT Gladwin
The Lancet 376 (9757), 2018-2031, 2010
20752010
Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation
K Cosby, KS Partovi, JH Crawford, RP Patel, CD Reiter, S Martyr, ...
Nature medicine 9 (12), 1498-1505, 2003
19182003
The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease
RP Rother, L Bell, P Hillmen, MT Gladwin
Jama 293 (13), 1653-1662, 2005
16172005
Pulmonary hypertension as a risk factor for death in patients with sickle cell disease
MT Gladwin, V Sachdev, ML Jison, Y Shizukuda, JF Plehn, K Minter, ...
New England Journal of Medicine 350 (9), 886-895, 2004
13822004
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
CD Reiter, X Wang, JE Tanus-Santos, N Hogg, RO Cannon, ...
Nature medicine 8 (12), 1383-1389, 2002
13182002
Right ventricular function and failure: report of a National Heart, Lung, and Blood Institute working group on cellular and molecular mechanisms of right heart failure
NF Voelkel, RA Quaife, LA Leinwand, RJ Barst, MD McGoon, ...
Circulation 114 (17), 1883-1891, 2006
13172006
Deconstructing sickle cell disease: reappraisal of the role of hemolysis in the development of clinical subphenotypes
GJ Kato, MT Gladwin, MH Steinberg
Blood reviews 21 (1), 37-47, 2007
8702007
Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease
CR Morris, GJ Kato, M Poljakovic, X Wang, WC Blackwelder, V Sachdev, ...
Jama 294 (1), 81-90, 2005
7742005
Cytoprotective effects of nitrite during in vivo ischemia-reperfusion of the heart and liver
MR Duranski, JJM Greer, A Dejam, S Jaganmohan, N Hogg, W Langston, ...
The Journal of clinical investigation 115 (5), 1232-1240, 2005
7632005
Nitrate and nitrite in biology, nutrition and therapeutics
JO Lundberg, MT Gladwin, A Ahluwalia, N Benjamin, NS Bryan, A Butler, ...
Nature chemical biology 5 (12), 865-869, 2009
6952009
Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell …
GJ Kato, V McGowan, RF Machado, JA Little, J Taylor, CR Morris, ...
Blood 107 (6), 2279-2285, 2006
6792006
The emerging biology of the nitrite anion
MT Gladwin, AN Schechter, DB Kim-Shapiro, RP Patel, N Hogg, S Shiva, ...
Nature chemical biology 1 (6), 308-314, 2005
6602005
Deoxymyoglobin is a nitrite reductase that generates nitric oxide and regulates mitochondrial respiration
S Shiva, Z Huang, R Grubina, J Sun, LA Ringwood, PH MacArthur, X Xu, ...
Circulation research 100 (5), 654-661, 2007
6222007
Nitrite augments tolerance to ischemia/reperfusion injury via the modulation of mitochondrial electron transfer
S Shiva, MN Sack, JJ Greer, M Duranski, LA Ringwood, L Burwell, ...
The Journal of experimental medicine 204 (9), 2089-2102, 2007
5882007
Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion
C Donadee, NJH Raat, T Kanias, J Tejero, JS Lee, EE Kelley, X Zhao, ...
Circulation 124 (4), 465-476, 2011
5702011
Hypoxia, red blood cells, and nitrite regulate NO-dependent hypoxic vasodilation
JH Crawford, TS Isbell, Z Huang, S Shiva, BK Chacko, AN Schechter, ...
Blood 107 (2), 566-574, 2006
5622006
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program
D Taliun, DN Harris, MD Kessler, J Carlson, ZA Szpiech, R Torres, ...
Nature 590 (7845), 290-299, 2021
5582021
Enzymatic function of hemoglobin as a nitrite reductase that produces NO under allosteric control
Z Huang, S Shiva, DB Kim-Shapiro, RP Patel, LA Ringwood, CE Irby, ...
The Journal of clinical investigation 115 (8), 2099-2107, 2005
5532005
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