|p53 regulates hematopoietic stem cell quiescence|
Y Liu, SE Elf, Y Miyata, G Sashida, Y Liu, G Huang, S Di Giandomenico, ...
Cell stem cell 4 (1), 37-48, 2009
|Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways|
T Tauchi, K Shin-Ya, G Sashida, M Sumi, A Nakajima, T Shimamoto, ...
Oncogene 22 (34), 5338-5347, 2003
|Telomeres and telomerase in hematologic neoplasia|
JH Ohyashiki, G Sashida, T Tauchi, K Ohyashiki
Oncogene 21 (4), 680-687, 2002
|Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia|
S Tanaka, S Miyagi, G Sashida, T Chiba, J Yuan, M Mochizuki-Kashio, ...
Blood, The Journal of the American Society of Hematology 120 (5), 1107-1117, 2012
|Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders|
T Muto, G Sashida, M Oshima, GR Wendt, M Mochizuki-Kashio, Y Nagata, ...
Journal of Experimental Medicine 210 (12), 2627-2639, 2013
|Ezh2 loss promotes development of myelodysplastic syndrome but attenuates its predisposition to leukaemic transformation|
G Sashida, H Harada, H Matsui, M Oshima, M Yui, Y Harada, S Tanaka, ...
Nature communications 5 (1), 4177, 2014
|Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner|
M Mochizuki-Kashio, K Aoyama, G Sashida, M Oshima, T Tomioka, ...
Blood, The Journal of the American Society of Hematology 126 (10), 1172-1183, 2015
|The loss of Ezh2 drives the pathogenesis of myelofibrosis and sensitizes tumor-initiating cells to bromodomain inhibition|
G Sashida, C Wang, T Tomioka, M Oshima, K Aoyama, A Kanai, ...
Journal of Experimental Medicine 213 (8), 1459-1477, 2016
|Loss of TET2 has dual roles in murine myeloproliferative neoplasms: disease sustainer and disease accelerator|
T Kameda, K Shide, T Yamaji, A Kamiunten, M Sekine, Y Taniguchi, ...
Blood, The Journal of the American Society of Hematology 125 (2), 304-315, 2015
|The ability of MLL to bind RUNX1 and methylate H3K4 at PU. 1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations|
G Huang, X Zhao, L Wang, S Elf, H Xu, X Zhao, G Sashida, Y Zhang, Y Liu, ...
Blood, The Journal of the American Society of Hematology 118 (25), 6544-6552, 2011
|The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior|
Y Liu, SE Elf, T Asai, Y Miyata, Y Liu, G Sashida, G Huang, ...
Cell cycle 8 (19), 3120-3124, 2009
|Inhibition of human telomerase enhances the effect of chemotherapeutic agents in lung cancer cells|
M Misawa, T Tauchi, G Sashida, A Nakajima, K Abe, JH Ohyashiki, ...
International journal of oncology 21 (5), 1087-1092, 2002
|Inhibition of human telomerase enhances the effect of the tyrosine kinase inhibitor, imatinib, in BCR-ABL-positive leukemia cells|
T Tauchi, A Nakajima, G Sashida, T Shimamoto, JH Ohyashiki, K Abe, ...
Clinical cancer research 8 (11), 3341-3347, 2002
|Akt Phosphorylates the Transcriptional Repressor Bmi1 to Block Its Effects on the Tumor-Suppressing Ink4a-Arf Locus|
Y Liu, F Liu, H Yu, X Zhao, G Sashida, A Deblasio, M Harr, QB She, ...
Science signaling 5 (247), ra77-ra77, 2012
|Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination|
T Yasuda, M Koiwa, A Yonemura, K Miyake, R Kariya, S Kubota, ...
Cell reports 34 (8), 2021
|BCL-2 antisense oligonucleotide genasense is active against imatinib-resistant BCR-ABL-positive cells|
T Tauchi, M Sumi, A Nakajima, G Sashida, T Shimamoto, K Ohyashiki
Clinical cancer research 9 (11), 4267-4273, 2003
|Epigenetic regulation of hematopoiesis|
G Sashida, A Iwama
International journal of hematology 96, 405-412, 2012
|Quantitative relationship between functionally active telomerase and major telomerase components (hTERT and hTR) in acute leukaemia cells|
JH Ohyashiki, H Hisatomi, K Nagao, S Honda, T Takaku, Y Zhang, ...
British journal of cancer 92 (10), 1942-1947, 2005
|Cyclin C regulates human hematopoietic stem/progenitor cell quiescence|
Y Miyata, Y Liu, V Jankovic, G Sashida, JM Lee, JH Shieh, T Naoe, ...
Stem cells 28 (2), 308-317, 2010
|Multifaceted role of the polycomb-group gene EZH2 in hematological malignancies|
G Sashida, A Iwama
International journal of hematology 105, 23-30, 2017