| The orphan G protein-coupled receptor GPR139 is activated by the peptides: adrenocorticotropic hormone (ACTH), α-, and β-melanocyte stimulating hormone (α-MSH, and β-MSH), and … AC Nøhr, MA Shehata, AS Hauser, V Isberg, J Mokrosinski, KB Andersen, ... Neurochemistry international 102, 105-113, 2017 | 41 | 2017 |
| GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain U Leurs, AB Klein, ED McSpadden, N Griem-Krey, SMØ Solbak, J Houlton, ... Proceedings of the National Academy of Sciences 118 (31), e2108079118, 2021 | 34 | 2021 |
| The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site AC Nøhr, W Jespers, MA Shehata, L Floryan, V Isberg, KB Andersen, ... Scientific reports 7 (1), 1128, 2017 | 28 | 2017 |
| Novel agonist bioisosteres and common structure-activity relationships for the orphan G protein-coupled receptor GPR139 MA Shehata, AC Nøhr, D Lissa, C Bisig, V Isberg, KB Andersen, ... Scientific Reports 6 (1), 36681, 2016 | 22 | 2016 |
| Identification of a novel scaffold for a small molecule GPR139 receptor agonist AC Nøhr, MA Shehata, D Palmer, R Pokhrel, M Vallianou, SR Foster, ... Scientific Reports 9 (1), 3802, 2019 | 11 | 2019 |
| Identification of the first surrogate agonists for the G protein-coupled receptor GPR132 MA Shehata, HB Christensen, V Isberg, DS Pedersen, A Bender, ... Rsc Advances 5 (60), 48551-48557, 2015 | 11 | 2015 |
| Exploring the NCS-382 Scaffold for CaMKIIα Modulation: Synthesis, Biochemical Pharmacology, and Biophysical Characterization of Ph-HTBA as a Novel High-Affinity Brain-Penetrant … Y Tian, MA Shehata, SJ Gauger, C Veronesi, L Hamborg, L Thiesen, ... Journal of Medicinal Chemistry 65 (22), 15066-15084, 2022 | 4 | 2022 |
| Discovery and Optimization of 5-Hydroxy-Diclofenac toward a New Class of Ligands with Nanomolar Affinity for the CaMKIIα Hub Domain Y Tian, MA Shehata, SJ Gauger, CKL Ng, S Solbak, L Thiesen, ... Journal of Medicinal Chemistry 65 (9), 6656-6676, 2022 | 4 | 2022 |
| The combination of fosfomycin, metronidazole, and recombinant human granulocyte-macrophage colony-stimulating factor is stable in vitro and has maintained antibacterial activity S Fonnes, BJ Holzknecht, LS Gasbjerg, JJ Weisser, HW Hallberg, M Arpi, ... Drug Research 68 (06), 349-354, 2018 | 3 | 2018 |
| Pregnenolone sulfate analogues differentially modulate GABAA receptor closed/desensitised states M Mortensen, Y Xu, MA Shehata, J Krall, M Ernst, B Frølund, TG Smart British Journal of Pharmacology 180 (19), 2482-2499, 2023 | | 2023 |
| GHB confers neuroprotection by stabilizing the CaMKIIα hub domain U Leurs, AB Klein, ED McSpadden, N Griem-Krey, SMØ Solbak, J Houlton, ... bioRxiv, 2020.09. 28.310474, 2020 | | 2020 |
| Novel Agonist Bioisosteres and Common Structure-Activity Relationships for The Orphan G Protein-Coupled Receptor GPR139 HBODEG Mohamed A. Shehata, Anne C. Nøhr, Delphine Lissa, Christoph Bisig ... Nature Scientific Reports, 2016 | | 2016 |
