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Toshihiko Sugiki
Toshihiko Sugiki
Laboratory of Analytical Chemistry, Pharmaceutical Sciences, Kitasato University
Verified email at kitasato-u.ac.jp
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Cited by
Year
Current NMR techniques for structure-based drug discovery
T Sugiki, K Furuita, T Fujiwara, C Kojima
Molecules 23 (1), 148, 2018
1422018
Impact of membrane curvature on amyloid aggregation
MS Terakawa, Y Lin, M Kinoshita, S Kanemura, D Itoh, T Sugiki, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1741-1764, 2018
1102018
Modern technologies of solution nuclear magnetic resonance spectroscopy for three-dimensional structure determination of proteins open avenues for life scientists
T Sugiki, N Kobayashi, T Fujiwara
Computational and structural biotechnology journal 15, 328-339, 2017
1032017
Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)
T Sugiki, K Takeuchi, T Yamaji, T Takano, Y Tokunaga, K Kumagai, ...
Journal of Biological Chemistry 287 (40), 33706-33718, 2012
632012
Identification of NDRG1 as an early inducible gene during in vitro maturation of cultured mast cells
Y Taketomi, T Sugiki, T Saito, S Ishii, M Hisada, T Suzuki-Nishimura, ...
Biochemical and biophysical research communications 306 (2), 339-346, 2003
602003
Model membrane size-dependent amyloidogenesis of Alzheimer's amyloid-β peptides
M Kinoshita, E Kakimoto, MS Terakawa, Y Lin, T Ikenoue, M So, T Sugiki, ...
Physical Chemistry Chemical Physics 19 (24), 16257-16266, 2017
502017
N-myc downregulated gene 1 is a phosphorylated protein in mast cells
T Sugiki, M Murakami, Y Taketomi, R Kikuchi-Yanoshita, I Kudo
Biological and Pharmaceutical Bulletin 27 (5), 624-627, 2004
462004
Isotopic Labeling of Heterologous Proteins in the Yeast Pichia pastoris and Kluyveromyces lactis
T Sugiki, O Ichikawa, M Miyazawa-Onami, I Shimada, H Takahashi
Protein NMR techniques, 19-36, 2012
412012
Association of N-myc downregulated gene 1 with heat-shock cognate protein 70 in mast cells
T Sugiki, Y Taketomi, R Kikuchi-Yanoshita, M Murakami, I Kudo
Biological and Pharmaceutical Bulletin 27 (5), 628-633, 2004
412004
Latest approaches for efficient protein production in drug discovery
T Sugiki, T Fujiwara, C Kojima
Expert opinion on drug discovery 9 (10), 1189-1204, 2014
402014
The crystal structure of the plant small GTPase OsRac1 reveals its mode of binding to NADPH oxidase
K Kosami, I Ohki, M Nagano, K Furuita, T Sugiki, Y Kawano, T Kawasaki, ...
Journal of Biological Chemistry 289 (41), 28569-28578, 2014
382014
Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-beta
T Sugiki
Biochemical and biophysical research communications 441 (2), 493-498, 2013
372013
Perdeuteration and methyl-selective 1H, 13C-labeling by using a Kluyveromyces lactis expression system
M Miyazawa-Onami, K Takeuchi, T Takano, T Sugiki, I Shimada, ...
Journal of biomolecular NMR 57, 297-304, 2013
372013
Membrane-induced initial structure of α-synuclein control its amyloidogenesis on model membranes
MS Terakawa, YH Lee, M Kinoshita, Y Lin, T Sugiki, N Fukui, T Ikenoue, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (3), 757-766, 2018
362018
Diverse structural conversion and aggregation pathways of Alzheimerʼs amyloid-β (1–40)
Y Lin, BR Sahoo, D Ozawa, M Kinoshita, J Kang, MH Lim, M Okumura, ...
ACS nano 13 (8), 8766-8783, 2019
332019
Amorphous aggregation of cytochrome c with inherently low amyloidogenicity is characterized by the metastability of supersaturation and the phase diagram
Y Lin, K Ishimori, Y Goto, YH Lee
Biophysical Journal 110 (3), 399a, 2016
272016
Stable isotope labeling of protein by Kluyveromyces lactis for NMR study
T Sugiki, I Shimada, H Takahashi
Journal of biomolecular NMR 42, 159-162, 2008
262008
Robust folding of a de novo designed ideal protein even with most of the core mutated to valine
R Koga, M Yamamoto, T Kosugi, N Kobayashi, T Sugiki, T Fujiwara, ...
Proceedings of the National Academy of Sciences 117 (49), 31149-31156, 2020
252020
Phosphoinositide binding by the PH domain in ceramide transfer protein (CERT) is inhibited by hyperphosphorylation of an adjacent serine-repeat motif
T Sugiki, D Egawa, K Kumagai, C Kojima, T Fujiwara, K Takeuchi, ...
Journal of Biological Chemistry 293 (28), 11206-11217, 2018
232018
Real-time assay method of lipid extraction activity
T Sugiki, H Takahashi, M Nagasu, K Hanada, I Shimada
Analytical biochemistry 399 (2), 162-167, 2010
222010
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