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Richard Southworth
Richard Southworth
Verified email at kcl.ac.uk
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Year
Mitochondrial uncoupling, with low concentration FCCP, induces ROS-dependent cardioprotection independent of KATP channel activation
JP Brennan, R Southworth, RA Medina, SM Davidson, MR Duchen, ...
Cardiovascular research 72 (2), 313-321, 2006
2732006
Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia‐reperfusion injury in heart
R Nederlof, O Eerbeek, MW Hollmann, R Southworth, CJ Zuurbier
British journal of pharmacology 171 (8), 2067-2079, 2014
1132014
Disruption of hexokinase II–mitochondrial binding blocks ischemic preconditioning and causes rapid cardiac necrosis
KMA Smeele, R Southworth, R Wu, C Xie, R Nederlof, A Warley, ...
Circulation research 108 (10), 1165-1169, 2011
942011
A reevaluation of the roles of hexokinase I and II in the heart
R Southworth, KAB Davey, A Warley, PB Garlick
American journal of physiology-heart and circulatory physiology 292 (1 …, 2007
752007
Renal vascular inflammation induced by Western diet in ApoE-null mice quantified by 19F NMR of VCAM-1 targeted nanobeacons
R Southworth, M Kaneda, J Chen, L Zhang, H Zhang, X Yang, R Razavi, ...
Nanomedicine: Nanotechnology, Biology and Medicine 5 (3), 359-367, 2009
732009
PET imaging of cardiac hypoxia: opportunities and challenges
MG Handley, RA Medina, E Nagel, PJ Blower, R Southworth
Journal of molecular and cellular cardiology 51 (5), 640-650, 2011
682011
Immunogold labeling study of the distribution of GLUT-1 and GLUT-4 in cardiac tissue following stimulation by insulin or ischemia
KAB Davey, PB Garlick, A Warley, R Southworth
American Journal of Physiology-Heart and Circulatory Physiology 292 (4 …, 2007
652007
An isolated perfused pig heart model for the development, validation and translation of novel cardiovascular magnetic resonance techniques
A Schuster, I Grünwald, A Chiribiri, R Southworth, M Ishida, G Hay, ...
Journal of Cardiovascular Magnetic Resonance 12 (1), 53, 2010
642010
Tissue‐specific differences in 2‐fluoro‐2‐deoxyglucose metabolism beyond FDG‐6‐P: a 19F NMR spectroscopy study in the rat
R Southworth, CR Parry, HG Parkes, RA Medina, PB Garlick
NMR in Biomedicine: An International Journal Devoted to the Development and …, 2003
612003
Monitoring of in vivo function of superparamagnetic iron oxide labelled murine dendritic cells during anti-tumour vaccination
R Tavare, P Sagoo, G Varama, Y Tanriver, A Warely, SS Diebold, ...
PloS one 6 (5), e19662, 2011
522011
Cardiac hypoxia imaging: second-generation analogues of 64Cu-ATSM
MG Handley, RA Medina, E Mariotti, GD Kenny, KP Shaw, R Yan, ...
Journal of Nuclear Medicine 55 (3), 488-494, 2014
492014
Multiple quantum filtered 23Na NMR in the Langendorff perfused mouse heart: Ratio of triple/double quantum filtered signals correlates with [Na] i
TR Eykyn, D Aksentijević, KL Aughton, R Southworth, W Fuller, ...
Journal of Molecular and Cellular Cardiology 86, 95-101, 2015
312015
64Cu-CTS: a promising radiopharmaceutical for the identification of low-grade cardiac hypoxia by PET
RA Medina, E Mariotti, D Pavlovic, KP Shaw, TR Eykyn, PJ Blower, ...
Journal of Nuclear Medicine 56 (6), 921-926, 2015
312015
Imaging of chemotherapy-induced acute cardiotoxicity with 18F-labeled lipophilic cations
SP McCluskey, A Haslop, C Coello, RN Gunn, EW Tate, R Southworth, ...
Journal of Nuclear Medicine 60 (12), 1750-1756, 2019
282019
Detection of anthracycline-induced cardiotoxicity using perfusion-corrected 99mTc sestamibi SPECT
ZM Safee, F Baark, ECT Waters, M Veronese, VR Pell, JE Clark, F Mota, ...
Scientific Reports 9 (1), 216, 2019
282019
Lactate-induced translocation of GLUT1 and GLUT4 is not mediated by the phosphatidylinositol-3-kinase pathway in the rat heart
RA Medina, R Southworth, W Fuller, PB Garlick
Basic research in cardiology 97, 168-176, 2002
272002
Hexokinase-mitochondrial interaction in cardiac tissue: implications for cardiac glucose uptake, the 18FDG lumped constant and cardiac protection
R Southworth
Journal of bioenergetics and biomembranes 41, 187-193, 2009
222009
Modeling non‐linear kinetics of hyperpolarized [1‐13C] pyruvate in the crystalloid‐perfused rat heart
E Mariotti, MR Orton, O Eerbeek, JF Ashruf, CJ Zuurbier, R Southworth, ...
NMR in Biomedicine 29 (4), 377-386, 2016
212016
Dissociation of glucose tracer uptake and glucose transporter distribution in the regionally ischaemic isolated rat heart: application of a new autoradiographic technique
R Southworth, JL Dearling, RA Medina, AA Flynn, BR Pedley, PB Garlick
European journal of nuclear medicine and molecular imaging 29, 1334-1341, 2002
212002
Developmental differences in superoxide production in isolated guinea-pig hearts during reperfusion
R Southworth, MJ Shattock, DJ Hearse, FJ Kelly
Journal of molecular and cellular cardiology 30 (7), 1391-1399, 1998
211998
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