CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity S Nishimura, I Manabe, M Nagasaki, K Eto, H Yamashita, M Ohsugi, ... Nature medicine 15 (8), 914-920, 2009 | 2650 | 2009 |
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance N Kamei, K Tobe, R Suzuki, M Ohsugi, T Watanabe, N Kubota, ... Journal of biological chemistry 281 (36), 26602-26614, 2006 | 1129 | 2006 |
RNA-methylation-dependent RNA processing controls the speed of the circadian clock JM Fustin, M Doi, Y Yamaguchi, H Hida, S Nishimura, M Yoshida, ... Cell 155 (4), 793-806, 2013 | 983 | 2013 |
Direct reciprocal effects of resistin and adiponectin on vascular endothelial cells: a new insight into adipocytokine–endothelial cell interactions D Kawanami, K Maemura, N Takeda, T Harada, T Nojiri, Y Imai, I Manabe, ... Biochemical and biophysical research communications 314 (2), 415-419, 2004 | 728 | 2004 |
Gene expression in fibroblasts and fibrosis: involvement in cardiac hypertrophy I Manabe, T Shindo, R Nagai Circulation research 91 (12), 1103-1113, 2002 | 709 | 2002 |
Macrophages in inflammation, repair and regeneration Y Oishi, I Manabe International immunology 30 (11), 511-528, 2018 | 700 | 2018 |
Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation K Eguchi, I Manabe, Y Oishi-Tanaka, M Ohsugi, N Kono, F Ogata, N Yagi, ... Cell metabolism 15 (4), 518-533, 2012 | 587 | 2012 |
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels S Nishimura, I Manabe, M Nagasaki, Y Hosoya, H Yamashita, H Fujita, ... Diabetes 56 (6), 1517-1526, 2007 | 553 | 2007 |
Krüppel-like transcription factor KLF5 is a key regulator of adipocyte differentiation Y Oishi, I Manabe, K Tobe, K Tsushima, T Shindo, K Fujiu, G Nishimura, ... Cell metabolism 1 (1), 27-39, 2005 | 548 | 2005 |
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling T Shindo, I Manabe, Y Fukushima, K Tobe, K Aizawa, S Miyamoto, ... Nature medicine 8 (8), 856-863, 2002 | 465 | 2002 |
Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload N Takeda, I Manabe, Y Uchino, K Eguchi, S Matsumoto, S Nishimura, ... The Journal of clinical investigation 120 (1), 254-265, 2010 | 436 | 2010 |
In vivo imaging in mice reveals local cell dynamics and inflammation in obese adipose tissue S Nishimura, I Manabe, M Nagasaki, K Seo, H Yamashita, Y Hosoya, ... The Journal of clinical investigation 118 (2), 710-721, 2008 | 350 | 2008 |
Chronic inflammation links cardiovascular, metabolic and renal diseases I Manabe Circulation Journal 75 (12), 2739-2748, 2011 | 331 | 2011 |
SREBP1 contributes to resolution of pro-inflammatory TLR4 signaling by reprogramming fatty acid metabolism Y Oishi, NJ Spann, VM Link, ED Muse, T Strid, C Edillor, MJ Kolar, ... Cell metabolism 25 (2), 412-427, 2017 | 318 | 2017 |
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity H Semba, N Takeda, T Isagawa, Y Sugiura, K Honda, M Wake, ... Nature communications 7 (1), 11635, 2016 | 315 | 2016 |
IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs S Nishimura, M Nagasaki, S Kunishima, A Sawaguchi, A Sakata, ... Journal of Cell Biology 209 (3), 453-466, 2015 | 293 | 2015 |
Adipose tissue inflammation in obesity and metabolic syndrome S Nishimura, I Manabe, R Nagai Discovery medicine, 2009 | 291 | 2009 |
Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice K Fujiu, I Manabe, R Nagai The Journal of clinical investigation 121 (9), 2011 | 282 | 2011 |
Adipose natural regulatory B cells negatively control adipose tissue inflammation S Nishimura, I Manabe, S Takaki, M Nagasaki, M Otsu, H Yamashita, ... Cell metabolism 18 (5), 759-766, 2013 | 272 | 2013 |
Obesity accelerates T cell senescence in murine visceral adipose tissue K Shirakawa, X Yan, K Shinmura, J Endo, M Kataoka, Y Katsumata, ... The Journal of clinical investigation 126 (12), 4626-4639, 2016 | 270 | 2016 |