ATR kinase activation mediated by MutSα and MutLα in response to cytotoxic O6-methylguanine adducts K Yoshioka, Y Yoshioka, P Hsieh Molecular cell 22 (4), 501-510, 2006 | 338 | 2006 |
DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development Y Ichijima, K Yoshioka, Y Yoshioka, K Shinohe, H Fujimori, J Unno, ... PloS one 5 (1), e8821, 2010 | 100 | 2010 |
ATM and SIRT6/SNF2H mediate transient H2AX stabilization when DSBs form by blocking HUWE1 to allow efficient γH2AX foci formation Y Atsumi, Y Minakawa, M Ono, S Dobashi, K Shinohe, A Shinohara, ... Cell reports 13 (12), 2728-2740, 2015 | 96 | 2015 |
Aberrations in DNA repair pathways in cancer and therapeutic significances A Motegi, M Masutani, KI Yoshioka, T Bessho Seminars in cancer biology 58, 29-46, 2019 | 73 | 2019 |
The mismatch repair‐mediated cell cycle checkpoint response to fluorodeoxyuridine A Liu, K Yoshioka, V Salerno, P Hsieh Journal of cellular biochemistry 105 (1), 245-254, 2008 | 62 | 2008 |
Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro Y Matsuno, Y Atsumi, A Shimizu, K Katayama, H Fujimori, M Hyodo, ... Nature communications 10 (1), 3925, 2019 | 45 | 2019 |
Differences in DNA recognition and conformational change activity between boxes A and B in HMG2 protein K Yoshioka, K Saito, T Tanabe, A Yamamoto, Y Ando, Y Nakamura, ... Biochemistry 38 (2), 589-595, 1999 | 44 | 1999 |
Onset of quiescence following p53 mediated down-regulation of H2AX in normal cells Y Atsumi, H Fujimori, H Fukuda, A Inase, K Shinohe, Y Yoshioka, ... PloS one 6 (8), e23432, 2011 | 39 | 2011 |
Induction of cancerous stem cells during embryonic stem cell differentiation H Fujimori, M Shikanai, H Teraoka, M Masutani, K Yoshioka Journal of Biological Chemistry 287 (44), 36777-36791, 2012 | 38 | 2012 |
The plant zinc finger protein ZPT2–2 has a unique mode of DNA interaction K Yoshioka, S Fukushima, T Yamazaki, M Yoshida, H Takatsuji Journal of Biological Chemistry 276 (38), 35802-35807, 2001 | 36 | 2001 |
Difference in affinity for DNA between HMG proteins 1 and 2 determined by surface plasmon resonance measurements A Yamamoto, Y Ando, K Yoshioka, K Saito, T Tanabe, H Shirakawa, ... The journal of biochemistry 122 (3), 586-594, 1997 | 33 | 1997 |
Genomic instability and cancer risk associated with erroneous DNA repair K Yoshioka, R Kusumoto-Matsuo, Y Matsuno, M Ishiai International journal of molecular sciences 22 (22), 12254, 2021 | 32 | 2021 |
The Arf/p53 protein module, which induces apoptosis, down-regulates histone H2AX to allow normal cells to survive in the presence of anti-cancer drugs Y Atsumi, A Inase, T Osawa, E Sugihara, R Sakasai, H Fujimori, ... Journal of Biological Chemistry 288 (19), 13269-13277, 2013 | 30 | 2013 |
Gamma‐irradiated quiescent cells repair directly induced double‐strand breaks but accumulate persistent double‐strand breaks during subsequent DNA replication Y Minakawa, Y Atsumi, A Shinohara, Y Murakami, K Yoshioka Genes to Cells 21 (7), 789-797, 2016 | 29 | 2016 |
Resveratrol and its related polyphenols contribute to the maintenance of genome stability Y Matsuno, Y Atsumi, M Alauddin, MM Rana, H Fujimori, M Hyodo, ... Scientific reports 10 (1), 5388, 2020 | 28 | 2020 |
Development of cancer-initiating cells and immortalized cells with genomic instability K Yoshioka, Y Atsumi, H Nakagama, H Teraoka World journal of stem cells 7 (2), 483, 2015 | 26 | 2015 |
Nucleosome linker proteins HMGB1 and histone H1 differentially enhance DNA ligation reactions S Yamanaka, E Katayama, K Yoshioka, S Nagaki, M Yoshida, H Teraoka Biochemical and biophysical research communications 292 (1), 268-273, 2002 | 25 | 2002 |
Sensitization of cancer cells to radiation and topoisomerase I inhibitor camptothecin using inhibitors of PARP and other signaling molecules Y Matsuno, M Hyodo, H Fujimori, A Shimizu, K Yoshioka Cancers 10 (10), 364, 2018 | 24 | 2018 |
pH-and salt-dependent self-assembly of human Rad51 protein analyzed as fluorescence resonance energy transfer between labeled proteins K Yoshioka, Y Yumoto-Yoshioka, F Fleury, M Takahashi Journal of biochemistry 133 (5), 593-597, 2003 | 21 | 2003 |
HMG box A in HMG2 protein functions as a mediator of DNA structural alteration together with box B Y Nakamura, K Yoshioka, H Shirakawa, M Yoshida The Journal of Biochemistry 129 (4), 643-651, 2001 | 16 | 2001 |