| Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis M Urushitani, A Sik, T Sakurai, N Nukina, R Takahashi, JP Julien Nature neuroscience 9 (1), 108-118, 2006 | 482 | 2006 |
| Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis M Urushitani, J Kurisu, K Tsukita, R Takahashi Journal of neurochemistry 83 (5), 1030-1042, 2002 | 339 | 2002 |
| Estradiol protects mesencephalic dopaminergic neurons from oxidative stress‐induced neuronal death H Sawada, M Ibi, T Kihara, M Urushitani, A Akaike, S Shimohama Journal of neuroscience research 54 (5), 707-719, 1998 | 324 | 1998 |
| Extracellular mutant SOD1 induces microglial‐mediated motoneuron injury W Zhao, DR Beers, JS Henkel, W Zhang, M Urushitani, JP Julien, ... Glia 58 (2), 231-243, 2010 | 309 | 2010 |
| Phosphatidylinositol 3‐kinase mediates neuroprotection by estrogen in cultured cortical neurons K Honda, H Sawada, T Kihara, M Urushitani, T Nakamizo, A Akaike, ... Journal of neuroscience research 60 (3), 321-327, 2000 | 302 | 2000 |
| Wild‐type superoxide dismutase acquires binding and toxic properties of ALS‐linked mutant forms through oxidation SA Ezzi, M Urushitani, JP Julien Journal of neurochemistry 102 (1), 170-178, 2007 | 280 | 2007 |
| Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis M Urushitani, SA Ezzi, JP Julien Proceedings of the National Academy of Sciences 104 (7), 2495-2500, 2007 | 280 | 2007 |
| Stimulation of α4β2 nicotinic acetylcholine receptors inhibits β-amyloid toxicity T Kihara, S Shimohama, M Urushitani, H Sawada, J Kimura, T Kume, ... Brain research 792 (2), 331-334, 1998 | 249 | 1998 |
| In vivo evidence of CHIP up‐regulation attenuating tau aggregation N Sahara, M Murayama, T Mizoroki, M Urushitani, Y Imai, R Takahashi, ... Journal of neurochemistry 94 (5), 1254-1263, 2005 | 238 | 2005 |
| Mechanisms of antiapoptotic effects of estrogens in nigral dopaminergic neurons H Sawada, M Ibi, T Kihara, M Urushitani, K Honda, M Nakanishi, A Akaike, ... The FASEB Journal 14 (9), 1202-1214, 2000 | 213 | 2000 |
| CHIP promotes proteasomal degradation of familial ALS‐linked mutant SOD1 by ubiquitinating Hsp/Hsc70 M Urushitani, J Kurisu, M Tateno, S Hatakeyama, KI Nakayama, S Kato, ... Journal of neurochemistry 90 (1), 231-244, 2004 | 209 | 2004 |
| Motor neuron-specific disruption of proteasomes, but not autophagy, replicates amyotrophic lateral sclerosis Y Tashiro, M Urushitani, H Inoue, M Koike, Y Uchiyama, M Komatsu, ... Journal of Biological Chemistry 287 (51), 42984-42994, 2012 | 182 | 2012 |
| Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model M Tateno, H Sadakata, M Tanaka, S Itohara, RM Shin, M Miura, ... Human molecular genetics 13 (19), 2183-2196, 2004 | 166 | 2004 |
| N‐methyl‐D‐aspartate receptor‐mediated mitochondrial Ca2+ overload in acute excitotoxic motor neuron death: A mechanism distinct from chronic neurotoxicity after Ca … M Urushitani, Tomoki, Nakamizo, R Inoue, H Sawada, T Kihara, K Honda, ... Journal of neuroscience research 63 (5), 377-387, 2001 | 165 | 2001 |
| Relationship between the tautomeric structures of curcumin derivatives and their Aβ-binding activities in the context of therapies for Alzheimer's disease D Yanagisawa, N Shirai, T Amatsubo, H Taguchi, K Hirao, M Urushitani, ... Biomaterials 31 (14), 4179-4185, 2010 | 164 | 2010 |
| Dopamine D2‐type agonists protect mesencephalic neurons from glutamate neurotoxicity: Mechanisms of neuroprotective treatment against oxidative stress H Sawada, M Ibi, T Kihara, M Urushitani, A Akaike, J Kimura, ... Annals of Neurology: Official Journal of the American Neurological …, 1998 | 150 | 1998 |
| Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP‐43 M Urushitani, T Sato, H Bamba, Y Hisa, I Tooyama Journal of neuroscience research 88 (4), 784-797, 2010 | 129 | 2010 |
| Neuroprotective mechanism of glial cell line‐derived neurotrophic factor in mesencephalic neurons H Sawada, M Ibi, T Kihara, M Urushitani, M Nakanishi, A Akaike, ... Journal of neurochemistry 74 (3), 1175-1184, 2000 | 127 | 2000 |
| Transplantation of M2-deviated microglia promotes recovery of motor function after spinal cord injury in mice S Kobashi, T Terashima, M Katagi, Y Nakae, J Okano, Y Suzuki, ... Molecular Therapy 28 (1), 254-265, 2020 | 121 | 2020 |
| The endoplasmic reticulum‐Golgi pathway is a target for translocation and aggregation of mutant superoxide dismutase linked to ALS M Urushitani, SA Ezzi, A Matsuo, I Tooyama, JP Julien The FASEB Journal 22 (7), 2476-2487, 2008 | 112 | 2008 |
Ryosuke TakahashiProfessor of Neurology, Kyoto University Graduate School of MedicineVerified email at kuhp.kyoto-u.ac.jp
