CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites Y Naito, K Hino, H Bono, K Ui-Tei Bioinformatics 31 (7), 1120-1123, 2015 | 1087 | 2015 |
Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference K Ui‐Tei, Y Naito, F Takahashi, T Haraguchi, H Ohki‐Hamazaki, A Juni, ... Nucleic acids research 32 (3), 936-948, 2004 | 1077 | 2004 |
siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference Y Naito, T Yamada, K Ui-Tei, S Morishita, K Saigo Nucleic acids research 32 (suppl_2), W124-W129, 2004 | 355 | 2004 |
Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors N Doi, S Zenno, R Ueda, H Ohki-Hamazaki, K Ui-Tei, K Saigo Current Biology 13 (1), 41-46, 2003 | 341 | 2003 |
Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target K Ui-Tei, S Zenno, Y Miyata, K Saigo FEBS letters 479 (3), 79-82, 2000 | 267 | 2000 |
siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect Y Naito, J Yoshimura, S Morishita, K Ui-Tei BMC bioinformatics 10, 1-8, 2009 | 230 | 2009 |
Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly … K Ui-Tei, Y Naito, S Zenno, K Nishi, K Yamato, F Takahashi, A Juni, ... Nucleic acids research 36 (7), 2136-2151, 2008 | 226 | 2008 |
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus K Nishi, A Nishi, T Nagasawa, K Ui-Tei Rna 19 (1), 17-35, 2013 | 208 | 2013 |
dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference Y Naito, T Yamada, T Matsumiya, K Ui-Tei, K Saigo, S Morishita Nucleic acids research 33 (suppl_2), W589-W591, 2005 | 208 | 2005 |
Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect K Ui-Tei, Y Naito, K Nishi, A Juni, K Saigo Nucleic acids research 36 (22), 7100-7109, 2008 | 195 | 2008 |
Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression K Usui-Aoki, H Ito, K Ui-Tei, K Takahashi, T Lukacsovich, W Awano, ... Nature cell biology 2 (8), 500-506, 2000 | 189 | 2000 |
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer K Yamato, T Yamada, M Kizaki, K Ui-Tei, Y Natori, M Fujino, T Nishihara, ... Cancer gene therapy 15 (3), 140-153, 2008 | 158 | 2008 |
Aph-1 contributes to the stabilization and trafficking of the γ-secretase complex through mechanisms involving intermolecular and intramolecular interactions M Niimura, N Isoo, N Takasugi, M Tsuruoka, K Ui-Tei, K Saigo, ... Journal of Biological Chemistry 280 (13), 12967-12975, 2005 | 156 | 2005 |
Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells N Sasaki, K Okishio, K Ui-Tei, K Saigo, A Kinoshita-Toyoda, H Toyoda, ... Journal of biological chemistry 283 (6), 3594-3606, 2008 | 133 | 2008 |
Characterization of voltage-gated calcium currents in gonadotropin-releasing hormone neurons tagged with green fluorescent protein in rats M Kato, K Ui-Tei, M Watanabe, Y Sakuma Endocrinology 144 (11), 5118-5125, 2003 | 118 | 2003 |
LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1 S Kojima, K Matsumoto, M Hirose, M Shimada, M Nagano, Y Shigeyoshi, ... Proceedings of the National Academy of Sciences 104 (6), 1859-1864, 2007 | 117 | 2007 |
Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants A Sato, T Kojima, K Ui-Tei, Y Miyata, K Saigo Development 126 (20), 4421-4430, 1999 | 114 | 1999 |
Molecular cloning and characterization of a novel 3′-phosphoadenosine 5′-phosphosulfate transporter, PAPST2 S Kamiyama, N Sasaki, E Goda, K Ui-Tei, K Saigo, H Narimatsu, Y Jigami, ... Journal of biological chemistry 281 (16), 10945-10953, 2006 | 105 | 2006 |
Robust and photocontrollable DNA capsules using azobenzenes F Tanaka, T Mochizuki, X Liang, H Asanuma, S Tanaka, K Suzuki, ... Nano letters 10 (9), 3560-3565, 2010 | 96 | 2010 |
Stability of miRNA 5′ terminal and seed regions is correlated with experimentally observed miRNA-mediated silencing efficacy N Hibio, K Hino, E Shimizu, Y Nagata, K Ui-Tei Scientific reports 2 (1), 996, 2012 | 91 | 2012 |