| Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases K Lefort, A Mandinova, P Ostano, V Kolev, V Calpini, I Kolfschoten, ... Genes & development 21 (5), 562-577, 2007 | 376 | 2007 |
| Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling B Hu, E Castillo, L Harewood, P Ostano, A Reymond, R Dummer, ... Cell 149 (6), 1207-1220, 2012 | 227 | 2012 |
| Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation MG Procopio, C Laszlo, D Al Labban, DE Kim, P Bordignon, SH Jo, ... Nature cell biology 17 (9), 1193-1204, 2015 | 210 | 2015 |
| Re-education of tumor-associated macrophages by CXCR2 blockade drives senescence and tumor inhibition in advanced prostate cancer D Di Mitri, M Mirenda, J Vasilevska, A Calcinotto, N Delaleu, A Revandkar, ... Cell reports 28 (8), 2156-2168. e5, 2019 | 155 | 2019 |
| A miR‐34a‐SIRT6 axis in the squamous cell differentiation network K Lefort, Y Brooks, P Ostano, M Cario‐André, V Calpini, ... The EMBO journal 32 (16), 2248-2263, 2013 | 148 | 2013 |
| Patient-derived ovarian tumor xenografts recapitulate human clinicopathology and genetic alterations F Ricci, F Bizzaro, M Cesca, F Guffanti, M Ganzinelli, A Decio, C Ghilardi, ... Cancer research 74 (23), 6980-6990, 2014 | 134 | 2014 |
| iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia A Chikh, RNH Matin, V Senatore, M Hufbauer, D Lavery, C Raimondi, ... The EMBO journal 30 (20), 4261-4273, 2011 | 101 | 2011 |
| ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-κB and drives prostate cancer progression N Longoni, M Sarti, D Albino, G Civenni, A Malek, E Ortelli, S Pinton, ... Cancer research 73 (14), 4533-4547, 2013 | 91 | 2013 |
| MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression C Dallavalle, D Albino, G Civenni, J Merulla, P Ostano, M Mello-Grand, ... The Journal of clinical investigation 126 (12), 4585-4602, 2016 | 86 | 2016 |
| Dualism of FGF and TGF-β signaling in heterogeneous cancer-associated fibroblast activation with ETV1 as a critical determinant P Bordignon, G Bottoni, X Xu, AS Popescu, Z Truan, E Guenova, L Kofler, ... Cell reports 28 (9), 2358-2372. e6, 2019 | 85 | 2019 |
| The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response A Mandinova, K Lefort, AT Di Vignano, W Stonely, P Ostano, G Chiorino, ... The EMBO journal 27 (8), 1243-1254, 2008 | 82 | 2008 |
| A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans A Mandinova, V Kolev, V Neel, B Hu, W Stonely, J Lieb, X Wu, C Colli, ... The Journal of clinical investigation 119 (10), 3127-3137, 2009 | 69 | 2009 |
| A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes S Kurinna, M Schäfer, P Ostano, E Karouzakis, G Chiorino, W Bloch, ... Nature communications 5 (1), 5099, 2014 | 68 | 2014 |
| Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer YS Brooks, P Ostano, SH Jo, J Dai, S Getsios, P Dziunycz, GFL Hofbauer, ... The Journal of clinical investigation 124 (5), 2260-2276, 2014 | 65 | 2014 |
| Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in melanoma lesions. E Maldi, C Travelli, A Caldarelli, N Agazzone, S Cintura, U Galli, ... Pigment cell & melanoma research 26 (1), 2013 | 64 | 2013 |
| Engineering an environment for the study of fibrosis: a 3D human muscle model with endothelium specificity and endomysium S Bersini, M Gilardi, GS Ugolini, V Sansoni, G Talo, S Perego, S Zanotti, ... Cell reports 25 (13), 3858-3868. e4, 2018 | 60 | 2018 |
| Thrombospondin‐1 is part of a Slug‐independent motility and metastatic program in cutaneous melanoma, in association with VEGFR‐1 and FGF‐2 P Borsotti, C Ghilardi, P Ostano, A Silini, R Dossi, D Pinessi, C Foglieni, ... Pigment cell & melanoma research 28 (1), 73-81, 2015 | 60 | 2015 |
| Cross-talk between myeloid-derived suppressor cells and mast cells mediates tumor-specific immunosuppression in prostate cancer E Jachetti, V Cancila, A Rigoni, L Bongiovanni, B Cappetti, B Belmonte, ... Cancer immunology research 6 (5), 552-565, 2018 | 53 | 2018 |
| Androgen receptor functions as transcriptional repressor of cancer-associated fibroblast activation A Clocchiatti, S Ghosh, MG Procopio, L Mazzeo, P Bordignon, P Ostano, ... The Journal of clinical investigation 128 (12), 5531-5548, 2018 | 52 | 2018 |
| TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D’Angelo, ... Nucleic acids research 47 (7), 3365-3382, 2019 | 44 | 2019 |
