Kevin Leder
Kevin Leder
Assistant Professor of Industrial and Systems Engineering, University of Minnesota
確認したメール アドレス:
Mathematical modeling of PDGF-driven glioblastoma reveals optimized radiation dosing schedules
K Leder, K Pitter, Q LaPlant, D Hambardzumyan, BD Ross, TA Chan, ...
Cell 156 (3), 603-616, 2014
Intratumor heterogeneity in evolutionary models of tumor progression
R Durrett, J Foo, K Leder, J Mayberry, F Michor
Genetics 188 (2), 461-477, 2011
Importance sampling for sums of random variables with regularly varying tails
P Dupuis, K Leder, H Wang
ACM Transactions on Modeling and Computer Simulation (TOMACS) 17 (3), 14-es, 2007
The impact of microenvironmental heterogeneity on the evolution of drug resistance in cancer cells
SM Mumenthaler, J Foo, NC Choi, N Heise, K Leder, DB Agus, W Pao, ...
Cancer informatics 14, CIN. S19338, 2015
The therapeutic implications of plasticity of the cancer stem cell phenotype
K Leder, EC Holland, F Michor
PloS one 5 (12), 2010
Fitness conferred by BCR-ABL kinase domain mutations determines the risk of pre-existing resistance in chronic myeloid leukemia
K Leder, J Foo, B Skaggs, M Gorre, CL Sawyers, F Michor
PloS one 6 (11), 2011
Evolutionary dynamics of tumor progression with random fitness values
R Durrett, J Foo, K Leder, J Mayberry, F Michor
Theoretical population biology 78 (1), 54-66, 2010
Evolutionary modeling of combination treatment strategies to overcome resistance to tyrosine kinase inhibitors in non-small cell lung cancer
SM Mumenthaler, J Foo, K Leder, NC Choi, DB Agus, W Pao, P Mallick, ...
Molecular pharmaceutics 8 (6), 2069-2079, 2011
Stochastic dynamics of cancer initiation
J Foo, K Leder, F Michor
Physical biology 8 (1), 015002, 2011
Multifocality and recurrence risk: a quantitative model of field cancerization
J Foo, K Leder, MD Ryser
Journal of theoretical biology 355, 170-184, 2014
Efficient Simulation of Light-Tailed Sums: an Old-Folk Song Sung to a Faster New Tune...
JH Blanchet, K Leder, PW Glynn
Monte Carlo and Quasi-Monte Carlo Methods 2008, 227-248, 2009
Optimization of radiation dosing schedules for proneural glioblastoma
H Badri, K Pitter, EC Holland, F Michor, K Leder
Journal of mathematical biology 72 (5), 1301-1336, 2016
Spatial Moran models, II: cancer initiation in spatially structured tissue
R Durrett, J Foo, K Leder
Journal of mathematical biology 72 (5), 1369-1400, 2016
Large deviations and importance sampling for a tandem network with slow-down
P Dupuis, K Leder, H Wang
Queueing Systems 57 (2-3), 71-83, 2007
Optimal radiotherapy dose schedules under parametric uncertainty
H Badri, Y Watanabe, K Leder
Physics in Medicine & Biology 61 (1), 338, 2015
On Lyapunov inequalities and subsolutions for efficient importance sampling
J Blanchet, P Glynn, K Leder
ACM Transactions on Modeling and Computer Simulation (TOMACS) 22 (3), 1-27, 2012
An evolutionary approach for identifying driver mutations in colorectal cancer
J Foo, LL Liu, K Leder, M Riester, Y Iwasa, C Lengauer, F Michor
PLoS computational biology 11 (9), 2015
A mathematical model of tumor growth and its response to single irradiation
Y Watanabe, EL Dahlman, KZ Leder, SK Hui
Theoretical Biology and Medical Modelling 13 (1), 6, 2016
Quantifying the dynamics of field cancerization in tobacco-related head and neck cancer: a multiscale modeling approach
MD Ryser, WT Lee, NE Ready, KZ Leder, J Foo
Cancer research 76 (24), 7078-7088, 2016
Cancer as a moving target: understanding the composition and rebound growth kinetics of recurrent tumors
J Foo, K Leder, SM Mumenthaler
Evolutionary applications 6 (1), 54-69, 2013
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