フォロー
Helena Coelho
Helena Coelho
UCIBIO
確認したメール アドレス: campus.fct.unl.pt
タイトル
引用先
引用先
Structural characterization of N‐linked glycans in the receptor binding domain of the SARS‐CoV‐2 spike protein and their interactions with human lectins
MP Lenza, I Oyenarte, T Diercks, JI Quintana, A Gimeno, H Coelho, ...
Angewandte Chemie 132 (52), 23971-23979, 2020
872020
Delineating Binding Modes of Gal/GalNAc and Structural Elements of the Molecular Recognition of Tumor‐Associated Mucin Glycopeptides by the Human Macrophage Galactose‐Type Lectin
F Marcelo, F Garcia‐Martin, T Matsushita, J Sardinha, H Coelho, ...
Chemistry–A European Journal 20 (49), 16147-16155, 2014
672014
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3
M de las Rivas, EJP Daniel, Y Narimatsu, I Compañón, K Kato, ...
Nature Chemical Biology, 2020
572020
Detection of tumor-associated glycopeptides by lectins: the peptide context modulates carbohydrate recognition
D Madariaga, N Martinez-Saez, VJ Somovilla, H Coelho, ...
ACS chemical biology 10 (3), 747-756, 2015
472015
The quest for anticancer vaccines: Deciphering the fine-epitope specificity of cancer-related monoclonal antibodies by combining microarray screening and Saturation Transfer …
H Coelho, T Matsushita, G Artigas, H Hinou, FJ Cañada, R Lo-Man, ...
Journal of the American Chemical Society 137 (39), 12438-12441, 2015
412015
The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences
M De Las Rivas, E Lira-Navarrete, EJP Daniel, I Compañón, H Coelho, ...
Nature communications 8 (1), 1959, 2017
392017
Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4
M De Las Rivas, EJ Paul Daniel, H Coelho, E Lira-Navarrete, L Raich, ...
ACS central science 4 (9), 1274-1290, 2018
372018
Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties
F Cochet, FA Facchini, L Zaffaroni, JM Billod, H Coelho, A Holgado, ...
Scientific reports 9 (1), 919, 2019
312019
The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose‐Type Lectin
A Diniz, H Coelho, JS Dias, SJ van Vliet, J Jiménez‐Barbero, F Corzana, ...
Chemistry–A European Journal 25 (61), 13945-13955, 2019
282019
Crystal structure of the carbohydrate recognition domain of the human macrophage galactose C-type lectin bound to GalNAc and the tumor-associated Tn antigen
A Gabba, A Bogucka, JG Luz, A Diniz, H Coelho, F Corzana, FJ Cañada, ...
Biochemistry 60 (17), 1327-1336, 2021
212021
Structural Analysis of a GalNAc‐T2 Mutant Reveals an Induced‐Fit Catalytic Mechanism for GalNAc‐Ts
M de Las Rivas, H Coelho, A Diniz, E Lira‐Navarrete, I Compañón, ...
Chemistry–A European Journal 24 (33), 8382-8392, 2018
212018
Glycans in infectious diseases. A molecular recognition perspective
L Unione, A Gimeno, P Valverde, I Calloni, H Coelho, S Mirabella, ...
Current medicinal chemistry 24 (36), 4057-4080, 2017
212017
Atomic and Specificity Details of Mucin 1 O-Glycosylation Process by Multiple Polypeptide GalNAc-Transferase Isoforms Unveiled by NMR and Molecular Modeling
H Coelho, M Rivas, AS Grosso, A Diniz, CO Soares, RA Francisco, ...
JACS Au 2 (3), 631-645, 2022
132022
Molecular Recognition Insights of Sialic Acid Glycans by Distinct Receptors Unveiled by NMR and Molecular Modeling
CO Soares, AS Grosso, J Ereño-Orbea, H Coelho, F Marcelo
Frontiers in Molecular Biosciences 8, 727847, 2021
132021
Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody
J Macías-León, IA Bermejo, A Asín, A García-García, I Compañón, ...
Chemical Communications 56 (96), 15137-15140, 2020
112020
Co‐administration of Antimicrobial Peptides Enhances Toll‐like Receptor 4 Antagonist Activity of a Synthetic Glycolipid
FA Facchini, H Coelho, SE Sestito, S Delgado, A Minotti, D Andreu, ...
ChemMedChem 13 (3), 280-287, 2018
82018
Peptidomimetic β-secretase inhibitors comprising a sequence of amyloid-β peptide for Alzheimer’s disease
H Vila-Real, H Coelho, J Rocha, A Fernandes, MR Ventura, CD Maycock, ...
Journal of medicinal chemistry 58 (14), 5408-5418, 2015
82015
Structural basis for the synthesis of the core 1 structure by C1GalT1
AM González-Ramírez, AS Grosso, Z Yang, I Compañón, H Coelho, ...
Nature Communications 13 (1), 2398, 2022
72022
Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody
MP Lenza, U Atxabal, C Nycholat, I Oyenarte, A Franconetti, JI Quintana, ...
JACS Au 3 (1), 204-215, 2022
62022
Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune‐Related Lectins
CDL Lima, H Coelho, A Gimeno, F Trovão, A Diniz, JS Dias, ...
Chemistry–A European Journal 27 (29), 7951-7958, 2021
62021
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