フォロー
Robert Lochhead, PhD
Robert Lochhead, PhD
Assistant Professor, Medical College of Wisconsin Department of Microbiology and Immunology
確認したメール アドレス: mcw.edu
タイトル
引用先
引用先
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis
BL Jutras, RB Lochhead, ZA Kloos, J Biboy, K Strle, CJ Booth, SK Govers, ...
Proceedings of the National Academy of Sciences 116 (27), 13498-13507, 2019
1352019
Lyme arthritis: linking infection, inflammation and autoimmunity
RB Lochhead, K Strle, SL Arvikar, JJ Weis, AC Steere
Nature Reviews Rheumatology 17 (8), 449-461, 2021
622021
Quorum sensing primes the oxidative stress response in the insect endosymbiont, Sodalis glossinidius
MH Pontes, M Babst, R Lochhead, K Oakeson, K Smith, C Dale
PloS one 3 (10), e3541, 2008
552008
MicroRNA-146a Provides Feedback Regulation of Lyme Arthritis but Not Carditis during Infection with Borrelia burgdorferi
RB Lochhead, Y Ma, JF Zachary, D Baltimore, JL Zhao, JH Weis, ...
PLoS pathogens 10 (6), e1004212, 2014
482014
Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected …
RB Lochhead, FL Sonderegger, Y Ma, JE Brewster, D Cornwall, ...
The Journal of Immunology 189 (5), 2488-2501, 2012
442012
MicroRNA expression shows inflammatory dysregulation and tumor‐like proliferative responses in joints of patients with postinfectious Lyme arthritis
RB Lochhead, K Strle, ND Kim, MJ Kohler, SL Arvikar, JM Aversa, ...
Arthritis & Rheumatology 69 (5), 1100-1110, 2017
362017
Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with postinfectious, Borrelia burgdorferi‐induced Lyme …
RB Lochhead, SL Arvikar, JM Aversa, RI Sadreyev, K Strle, AC Steere
Cellular microbiology 21 (2), e12954, 2019
342019
Interferon‐gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast‐like synoviocytes into immune effector cells
RB Lochhead, D Ordoñez, SL Arvikar, JM Aversa, LS Oh, B Heyworth, ...
Cellular microbiology 21 (2), e12992, 2019
332019
Borrelia burgdorferi Arthritis–Associated Locus Bbaa1 Regulates Lyme Arthritis and K/B× N Serum Transfer Arthritis through Intrinsic Control of Type I IFN Production
Y Ma, KKC Bramwell, RB Lochhead, JK Paquette, JF Zachary, JH Weis, ...
The Journal of Immunology 193 (12), 6050-6060, 2014
282014
Antagonistic interplay between microRNA-155 and IL-10 during Lyme carditis and arthritis
RB Lochhead, JF Zachary, L Dalla Rosa, Y Ma, JH Weis, RM O’Connell, ...
PLoS One 10 (8), e0135142, 2015
252015
Correlation of Lyme disease–associated IgG4 autoantibodies with synovial pathology in antibiotic‐refractory Lyme arthritis
KB Sulka, K Strle, JT Crowley, RB Lochhead, R Anthony, AC Steere
Arthritis & Rheumatology 70 (11), 1835-1846, 2018
172018
Report of the pathogenesis and pathophysiology of Lyme disease subcommittee of the HHS Tick Borne Disease Working Group
ST Donta, WA Adams, T Bankhead, N Baumgarth, ME Embers, ...
Frontiers in Medicine 8, 643235, 2021
82021
Autoimmunity to synovial extracellular matrix proteins in patients with postinfectious Lyme arthritis
K Kanjana, K Strle, RB Lochhead, A Pianta, LM Mateyka, Q Wang, ...
The Journal of Clinical Investigation 133 (17), 2023
52023
Peptidoglycan in osteoarthritis synovial tissue is associated with joint inflammation
MN Holub, A Wahhab, JR Rouse, R Danner, LG Hackner, CB Duris, ...
Arthritis Research & Therapy 26 (1), 77, 2024
42024
Cell‐Mediated Cytotoxicity in Lyme Arthritis
D Ordóñez, RB Lochhead, K Strle, A Pianta, S Arvikar, I Van Rhijn, ...
Arthritis & Rheumatology 75 (5), 782-793, 2023
32023
Immune fibroblasts are unconventional antigen presenting cells and nonprofessional phagocytes in Lyme arthritis
RB Lochhead, R Danner, A Wahhab, J Rouse
The Journal of Immunology 204 (1_Supplement), 148.29-148.29, 2020
22020
Extracellular micrornas in synovial fluid reveal a marked proliferative signature in patients with antibiotic-refractory lyme arthritis
RB Lochhead, ND Kim, S Arvikar, K Strle, AC Steere
ARTHRITIS & RHEUMATOLOGY 67, 2015
22015
Borrelia burgdorferi peptidoglycan triggers inflammatory responses in Lyme arthritis
J Rouse, A Wahhab, R Danner, B Jutras, R Lochhead
The Journal of Immunology 206 (1_Supplement), 52.17-52.17, 2021
12021
Microvesicle-associated hsa-miR-223-3p is elevated in rheumatoid synovial fluid compared with osteoarthritis synovial fluid
ND Kim, RB Lochhead, P Schmit, MJ Kohler, AD Luster
ARTHRITIS & RHEUMATOLOGY 67, 2015
12015
MicroRNAs and type I interferon are critical immune modulators in Lyme arthritis
RB Lochhead Jr
The University of Utah, 2014
12014
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論文 1–20