Mohamed S. Nafie, PhD, MRSC
Mohamed S. Nafie, PhD, MRSC
Assistant professor of Bioorganic Chemistry, College of Sciences, University of Sharjah (UAE)
Verified email at - Homepage
Cited by
Cited by
Auspicious role of the steroidal heterocyclic derivatives as a platform for anti-cancer drugs
MA Tantawy, MS Nafie, GA Elmegeed, IAI Ali
Bioorganic chemistry 73, 128-146, 2017
Triaryl dicationic DNA minor-groove binders with antioxidant activity display cytotoxicity and induce apoptosis in breast cancer
MS Nafie, K Arafa, NK Sedky, AA Alakhdar, RK Arafa
Chemico-biological interactions 324, 109087, 2020
Screening of different drug design tools to predict the mode of action of steroidal derivatives as anti-cancer agents
MS Nafie, MA Tantawy, GA Elmgeed
Steroids 152, 108485, 2019
Discovery of novel pyrazolo [3, 4-b] pyridine scaffold-based derivatives as potential PIM-1 kinase inhibitors in breast cancer MCF-7 cells
MS Nafie, AM Amer, AK Mohamed, ES Tantawy
Bioorganic & Medicinal Chemistry 28 (24), 115828, 2020
Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro …
EM Gad, MS Nafie, EH Eltamany, MSAG Hammad, A Barakat, ATA Boraei
Molecules 25 (11), 2523, 2020
Synthesis, characterization of some pyrazine derivatives as anti-cancer agents: In vitro and in Silico approaches
ES Tantawy, AM Amer, EK Mohamed, MM Abd Alla, MS Nafie
Journal of Molecular Structure 1210, 128013, 2020
Molecular docking, anti-proliferative activity and induction of apoptosis in human liver cancer cells treated with androstane derivatives: Implication of PI3K/AKT/mTOR pathway
SW Kattan, MS Nafie, GA Elmgeed, W Alelwani, M Badar, MA Tantawy
The Journal of Steroid Biochemistry and Molecular Biology 198, 105604, 2020
Synthesis, molecular modeling and anti-cancer evaluation of a series of quinazoline derivatives
AI Khodair, MA Alsafi, MS Nafie
Carbohydrate research 486, 107832, 2019
Topo II inhibition and DNA intercalation by new phthalazine-based derivatives as potent anticancer agents: design, synthesis, anti-proliferative, docking, and in vivo studies
MM Khalifa, AA Al-Karmalawy, EB Elkaeed, MS Nafie, MA Tantawy, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 299-314, 2022
Exploration of novel VEGFR2 tyrosine kinase inhibitors via design and synthesis of new alkylated indolyl-triazole Schiff bases for targeting breast cancer
MS Nafie, ATA Boraei
Bioorganic Chemistry 122, 105708, 2022
Synthesis of new substituted pyridine derivatives as potent anti-liver cancer agents through apoptosis induction: In vitro, in vivo, and in silico integrated approaches
ATA Boraei, EH Eltamany, IAI Ali, SM Gebriel, MS Nafie
Bioorganic Chemistry 111, 104877, 2021
Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity
HSA ElZahabi, MS Nafie, D Osman, NH Elghazawy, DH Soliman, ...
European Journal of Medicinal Chemistry 222, 113609, 2021
Chemical Profiling, Antioxidant, Cytotoxic Activities and Molecular Docking Simulation of Carrichtera annua DC. (Cruciferae)
EE Eltamany, SS Elhady, HA Ahmed, JM Badr, AO Noor, SA Ahmed, ...
Antioxidants 9 (12), 1286, 2020
Antimicrobial and antiproliferative activities of novel synthesized 6‐(quinolin‐2‐ylthio) pyridine derivatives with molecular docking study as multi‐targeted JAK2/STAT3 inhibitors
MS Nafie, S Mahgoub, AM Amer
Chemical Biology & Drug Design 97 (3), 553-564, 2021
Molecular insights into human transmembrane protease serine-2 (TMPS2) inhibitors against SARS-CoV2: homology modelling, molecular dynamics, and docking studies
SM Kishk, RM Kishk, ASA Yassen, MS Nafie, NA Nemr, G ElMasry, ...
Molecules 25 (21), 5007, 2020
Design and synthesis of novel benzoazoninone derivatives as potential CBSIs and apoptotic inducers: in vitro, in vivo, molecular docking, molecular dynamics, and SAR studies
MM Hammouda, AA Elmaaty, MS Nafie, M Abdel-Motaal, NS Mohamed, ...
Bioorganic Chemistry 127, 105995, 2022
Discovery of hydrazide-based pyridazino [4, 5-b] indole scaffold as a new phosphoinositide 3-kinase (PI3K) inhibitor for breast cancer therapy
AAM Sarhan, ATA Boraei, A Barakat, MS Nafie
RSC advances 10 (33), 19534-19541, 2020
Ligand-based design on the dog-bone-shaped BIBR1532 pharmacophoric features and synthesis of novel analogues as promising telomerase inhibitors with in vitro and in vivo …
AA Al-Karmalawy, MS Nafie, MA Shaldam, AA Elmaaty, SA Antar, ...
Journal of Medicinal Chemistry 66 (1), 777-792, 2022
Novel Bis-Thiazole Derivatives: Synthesis and Potential Cytotoxic Activity Through Apoptosis With Molecular Docking Approaches
KM Dawood, MA Raslan, AA Abbas, BE Mohamed, MH Abdellattif, ...
Frontiers in Chemistry 9, 694870, 2021
Rubia tinctorum root extracts: Chemical profile and management of type II diabetes mellitus
EE Eltamany, MS Nafie, DM Khodeer, AHH El-Tanahy, MS Abdel-Kader, ...
RSC advances 10 (41), 24159-24168, 2020
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