The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation G Leprivier, M Remke, B Rotblat, A Dubuc, ARF Mateo, M Kool, ... Cell 153 (5), 1064-1079, 2013 | 434 | 2013 |
HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response B Rotblat, AL Southwell, DE Ehrnhoefer, NH Skotte, M Metzler, ... Proceedings of the National Academy of Sciences 111 (8), 3032-3037, 2014 | 104 | 2014 |
Contributions of counter-charge in a potassium channel voltage-sensor domain SA Pless, JD Galpin, AP Niciforovic, CA Ahern Nature chemical biology 7 (9), 617-623, 2011 | 101 | 2011 |
Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels SA Pless, JD Galpin, A Frankel, CA Ahern Nature communications 2 (1), 351, 2011 | 100 | 2011 |
Atomic basis for therapeutic activation of neuronal potassium channels RY Kim, MC Yau, JD Galpin, G Seebohm, CA Ahern, SA Pless, HT Kurata Nature communications 6 (1), 8116, 2015 | 81 | 2015 |
Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels SA Pless, JD Galpin, AP Niciforovic, HT Kurata, CA Ahern Elife 2, e01289, 2013 | 64 | 2013 |
Intermediate state trapping of a voltage sensor JJ Lacroix, SA Pless, L Maragliano, FV Campos, JD Galpin, CA Ahern, ... Journal of General Physiology 140 (6), 635-652, 2012 | 60 | 2012 |
Synthesis of enzymatically active human α‐l‐iduronidase in Arabidopsis cgl (complex glycan‐deficient) seeds WL Downing, JD Galpin, S Clemens, SM Lauzon, AL Samuels, ... Plant biotechnology journal 4 (2), 169-181, 2006 | 60 | 2006 |
Identification and quantification of newly synthesized proteins translationally regulated by YB-1 using a novel Click–SILAC approach SP Somasekharan, N Stoynov, B Rotblat, G Leprivier, JD Galpin, ... Journal of proteomics 77, e1-e10, 2012 | 52 | 2012 |
Production of active human glucocerebrosidase in seeds of Arabidopsis thaliana complex-glycan-deficient (cgl) plants X He, JD Galpin, MB Tropak, D Mahuran, T Haselhorst, M Von Itzstein, ... Glycobiology 22 (4), 492-503, 2012 | 52 | 2012 |
Asymmetric functional contributions of acidic and aromatic side chains in sodium channel voltage-sensor domains SA Pless, FD Elstone, AP Niciforovic, JD Galpin, R Yang, HT Kurata, ... Journal of General Physiology 143 (5), 645-656, 2014 | 41 | 2014 |
Atomic determinants of BK channel activation by polyunsaturated fatty acids Y Tian, M Aursnes, TV Hansen, JE Tungen, JD Galpin, L Leisle, CA Ahern, ... Proceedings of the National Academy of Sciences 113 (48), 13905-13910, 2016 | 38 | 2016 |
Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid X Steinberg, MA Kasimova, D Cabezas-Bratesco, JD Galpin, ... Elife 6, e28626, 2017 | 33 | 2017 |
Charge-accelerated cope rearrangements of 3-amino-1, 5-dienes TJ Spules, JD Galpin, D Macdonald Tetrahedron letters 34 (2), 247-250, 1993 | 33 | 1993 |
Cellular encoding of Cy dyes for single-molecule imaging L Leisle, R Chadda, JD Lueck, DT Infield, JD Galpin, V Krishnamani, ... Elife 5, e19088, 2016 | 27 | 2016 |
Contributions of conserved residues at the gating interface of glycine receptors SA Pless, AWY Leung, JD Galpin, CA Ahern Journal of Biological Chemistry 286 (40), 35129-35136, 2011 | 24 | 2011 |
Atomic mutagenesis in ion channels with engineered stoichiometry JD Lueck, AL Mackey, DT Infield, JD Galpin, J Li, B Roux, CA Ahern Elife 5, e18976, 2016 | 21 | 2016 |
A novel mechanism for fine-tuning open-state stability in a voltage-gated potassium channel SA Pless, AP Niciforovic, JD Galpin, JJ Nunez, HT Kurata, CA Ahern Nature communications 4 (1), 1784, 2013 | 20 | 2013 |
HIFs: New arginine mimic inhibitors of the Hv1 channel with improved VSD–ligand interactions C Zhao, L Hong, JD Galpin, S Riahi, VT Lim, PD Webster, DJ Tobias, ... Journal of General Physiology 153 (9), e202012832, 2021 | 17 | 2021 |
Divergent Cl- and H+ pathways underlie transport coupling and gating in CLC exchangers and channels L Leisle, Y Xu, E Fortea, S Lee, JD Galpin, M Vien, CA Ahern, A Accardi, ... Elife 9, e51224, 2020 | 17 | 2020 |