Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions KT Simons, C Kooperberg, E Huang, D Baker Journal of molecular biology 268 (1), 209-225, 1997 | 1721 | 1997 |
Physiochemical drug properties associated with in vivo toxicological outcomes JD Hughes, J Blagg, DA Price, S Bailey, GA DeCrescenzo, RV Devraj, ... Bioorganic & medicinal chemistry letters 18 (17), 4872-4875, 2008 | 938 | 2008 |
Structure-based maximal affinity model predicts small-molecule druggability AC Cheng, RG Coleman, KT Smyth, Q Cao, P Soulard, DR Caffrey, ... Nature biotechnology 25 (1), 71-75, 2007 | 767 | 2007 |
Are protein–protein interfaces more conserved in sequence than the rest of the protein surface? DR Caffrey, S Somaroo, JD Hughes, J Mintseris, ES Huang Protein Science 13 (1), 190-202, 2004 | 458 | 2004 |
Protein folding: the endgame M Levitt, M Gerstein, E Huang, S Subbiah, J Tsai Annual review of biochemistry 66 (1), 549-579, 1997 | 277 | 1997 |
The chemical state of gallium in working alkane dehydrocyclodimerization catalysts. In situ gallium K-edge X-ray absorption spectroscopy GD Meitzner, E Iglesia, JE Baumgartner, ES Huang Journal of catalysis 140 (1), 209-225, 1993 | 259 | 1993 |
Ab initio construction of protein tertiary structures using a hierarchical approach Y Xia, ES Huang, M Levitt, R Samudrala Journal of molecular biology 300 (1), 171-185, 2000 | 220 | 2000 |
Factors affecting the ability of energy functions to discriminate correct from incorrect folds BH Park, ES Huang, M Levitt Journal of molecular biology 266 (4), 831-846, 1997 | 210 | 1997 |
Structure-based druggability assessment—identifying suitable targets for small molecule therapeutics EB Fauman, BK Rai, ES Huang Current opinion in chemical biology 15 (4), 463-468, 2011 | 195 | 2011 |
Recognizing native folds by the arrangement of hydrophobic and polar residues ES Huang, S Subbiah, M Levitt Journal of molecular biology 252 (5), 709-720, 1995 | 181 | 1995 |
Causal reasoning on biological networks: interpreting transcriptional changes L Chindelevitch, D Ziemek, A Enayetallah, R Randhawa, B Sidders, ... Bioinformatics 28 (8), 1114-1121, 2012 | 149 | 2012 |
Ab initio protein structure prediction using a combined hierarchical approach R Samudrala, Y Xia, E Huang, M Levitt Proteins: Structure, Function, and Bioinformatics 37 (S3), 194-198, 1999 | 147 | 1999 |
The role of turns in the structure of an α-helical protein AP Brunet, ES Huang, ME Huffine, JE Loeb, RJ Weltman, MH Hecht Nature 364 (6435), 355-358, 1993 | 140 | 1993 |
Ab initio fold prediction of small helical proteins using distance geometry and knowledge-based scoring functions ES Huang, R Samudrala, JW Ponder Journal of molecular biology 290 (1), 267-281, 1999 | 114 | 1999 |
Using a hydrophobic contact potential to evaluate native and near-native folds generated by molecular dynamics simulations ES Huang, S Subbiah, J Tsai, M Levitt Journal of molecular biology 257 (3), 716-725, 1996 | 102 | 1996 |
A combined approach for ab initio construction of low resolution protein tertiary structures from sequence R Samudrala, Y Xia, M LEVITT, ES Huang Biocomputing'99, 505-516, 1999 | 96 | 1999 |
Beyond data integration T Slater, C Bouton, ES Huang Drug discovery today 13 (13-14), 584-589, 2008 | 75 | 2008 |
PFAAT version 2.0: a tool for editing, annotating, and analyzing multiple sequence alignments DR Caffrey, PH Dana, V Mathur, M Ocano, EJ Hong, YE Wang, ... BMC bioinformatics 8, 1-7, 2007 | 69 | 2007 |
Construction of a sequence motif characteristic of aminergic G protein–coupled receptors ES Huang Protein Science 12 (7), 1360-1367, 2003 | 67 | 2003 |
Accuracy of side‐chain prediction upon near‐native protein backbones generated by ab initio folding methods ES Huang, P Koehl, M Levitt, RV Pappu, JW Ponder Proteins: Structure, Function, and Bioinformatics 33 (2), 204-217, 1998 | 65 | 1998 |