フォロー
Keisuke Ueda
Keisuke Ueda
Graduate School of Pharmaceutical Sciences, Chiba University
確認したメール アドレス: chiba-u.jp - ホームページ
タイトル
引用先
引用先
The effect of HPMCAS functional groups on drug crystallization from the supersaturated state and dissolution improvement
K Ueda, K Higashi, K Yamamoto, K Moribe
International journal of pharmaceutics 464 (1-2), 205-213, 2014
1252014
Inhibitory effect of hydroxypropyl methylcellulose acetate succinate on drug recrystallization from a supersaturated solution assessed using nuclear magnetic resonance measurements
K Ueda, K Higashi, K Yamamoto, K Moribe
Molecular pharmaceutics 10 (10), 3801-3811, 2013
1162013
Recent progress of structural study of polymorphic pharmaceutical drugs
K Higashi, K Ueda, K Moribe
Advanced drug delivery reviews 117, 71-85, 2017
902017
Self‐Degradable Lipid‐Like Materials Based on “Hydrolysis accelerated by the intra‐Particle Enrichment of Reactant (HyPER)” for Messenger RNA Delivery
H Tanaka, T Takahashi, M Konishi, N Takata, M Gomi, D Shirane, ...
Advanced Functional Materials 30 (34), 1910575, 2020
782020
Mechanistic differences in permeation behavior of supersaturated and solubilized solutions of carbamazepine revealed by nuclear magnetic resonance measurements
K Ueda, K Higashi, W Limwikrant, S Sekine, T Horie, K Yamamoto, ...
Molecular pharmaceutics 9 (11), 3023-3033, 2012
732012
Synergetic role of hypromellose and methacrylic acid copolymer in the dissolution improvement of amorphous solid dispersions
N Ohyagi, K Ueda, K Higashi, K Yamamoto, K Kawakami, K Moribe
Journal of pharmaceutical sciences 106 (4), 1042-1050, 2017
532017
Nano-scale and molecular-level understanding of wet-milled indomethacin/poloxamer 407 nanosuspension with TEM, suspended-state NMR, and Raman measurements
Y Kuroiwa, K Higashi, K Ueda, K Yamamoto, K Moribe
International journal of pharmaceutics 537 (1-2), 30-39, 2018
432018
An insight into different stabilization mechanisms of phenytoin derivatives supersaturation by HPMC and PVP
N Otsuka, K Ueda, N Ohyagi, K Shimizu, K Katakawa, T Kumamoto, ...
Journal of pharmaceutical sciences 104 (8), 2574-2582, 2015
422015
Polymer type impacts amorphous solubility and drug-rich phase colloidal stability: A mechanistic study using nuclear magnetic resonance spectroscopy
K Ueda, LS Taylor
Molecular Pharmaceutics 17 (4), 1352-1362, 2020
412020
DNA-loaded nano-adjuvant formed with a vitamin E-scaffold intracellular environmentally-responsive lipid-like material for cancer immunotherapy
M Kawai, T Nakamura, N Miura, M Maeta, H Tanaka, K Ueda, K Higashi, ...
Nanomedicine: Nanotechnology, Biology and Medicine 14 (8), 2587-2597, 2018
412018
Direct NMR monitoring of phase separation behavior of highly supersaturated nifedipine solution stabilized with hypromellose derivatives
K Ueda, K Higashi, K Moribe
Molecular pharmaceutics 14 (7), 2314-2322, 2017
412017
Inhibition mechanism of hydroxypropyl methylcellulose acetate succinate on drug crystallization in gastrointestinal fluid and drug permeability from a supersaturated solution
K Ueda, K Higashi, M Kataoka, S Yamashita, K Yamamoto, K Moribe
European Journal of Pharmaceutical Sciences 62, 293-300, 2014
412014
Equilibrium State at Supersaturated Drug Concentration Achieved by Hydroxypropyl Methylcellulose Acetate Succinate: Molecular Characterization Using 1H NMR …
K Ueda, K Higashi, K Yamamoto, K Moribe
Molecular pharmaceutics 12 (4), 1096-1104, 2015
402015
Impact of hypromellose acetate succinate grade on drug amorphous solubility and in vitro membrane transport
K Ueda, SS Hate, LS Taylor
Journal of pharmaceutical sciences 109 (8), 2464-2473, 2020
382020
Effect of Drug-Polymer Interactions through Hypromellose Acetate Succinate Substituents on the Physical Stability on Solid Dispersions Studied by Fourier-Transform Infrared and …
Y Ishizuka, K Ueda, H Okada, J Takeda, M Karashima, K Yazawa, ...
Molecular pharmaceutics 16 (6), 2785-2794, 2019
382019
Cryo-TEM and AFM observation of the time-dependent evolution of amorphous probucol nanoparticles formed by the aqueous dispersion of ternary solid dispersions
Z Zhao, H Katai, K Higashi, K Ueda, K Kawakami, K Moribe
Molecular pharmaceutics 16 (5), 2184-2198, 2019
372019
Mechanism of enhanced nifedipine dissolution by polymer-blended solid dispersion through molecular-level characterization
K Ueda, C Yamazoe, Y Yasuda, K Higashi, K Kawakami, K Moribe
Molecular pharmaceutics 15 (9), 4099-4109, 2018
372018
Molecular mobility suppression of ibuprofen-rich amorphous nanodroplets by HPMC revealed by NMR relaxometry and its significance with respect to crystallization inhibition
K Ueda, N Yamamoto, K Higashi, K Moribe
Molecular Pharmaceutics 16 (12), 4968-4977, 2019
352019
Drug solubilization mechanism of α-glucosyl stevia by NMR spectroscopy
J Zhang, K Higashi, K Ueda, K Kadota, Y Tozuka, W Limwikrant, ...
International journal of pharmaceutics 465 (1-2), 255-261, 2014
342014
Mechanistic elucidation of formation of drug-rich amorphous nanodroplets by dissolution of the solid dispersion formulation
K Ueda, K Higashi, K Moribe
International journal of pharmaceutics 561, 82-92, 2019
322019
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