“Breakthrough” dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time AN Samaha, P Seeman, J Stewart, H Rajabi, S Kapur Journal of Neuroscience 27 (11), 2979-2986, 2007 | 316 | 2007 |
Amphetamine or cocaine limits the ability of later experience to promote structural plasticity in the neocortex and nucleus accumbens B Kolb, G Gorny, Y Li, AN Samaha, TE Robinson Proceedings of the National Academy of Sciences 100 (18), 10523-10528, 2003 | 263 | 2003 |
Why does the rapid delivery of drugs to the brain promote addiction? AN Samaha, TE Robinson Trends in pharmacological sciences 26 (2), 82-87, 2005 | 261 | 2005 |
Antipsychotic-induced dopamine supersensitivity psychosis: pharmacology, criteria, and therapy G Chouinard, AN Samaha, VA Chouinard, CS Peretti, N Kanahara, ... Psychotherapy and psychosomatics 86 (4), 189-219, 2017 | 240 | 2017 |
How fast and how often: The pharmacokinetics of drug use are decisive in addiction F Allain, EA Minogianis, DCS Roberts, AN Samaha Neuroscience & Biobehavioral Reviews 56, 166-179, 2015 | 199 | 2015 |
The rate of cocaine administration alters gene regulation and behavioral plasticity: implications for addiction AN Samaha, N Mallet, SM Ferguson, F Gonon, TE Robinson Journal of Neuroscience 24 (28), 6362-6370, 2004 | 145 | 2004 |
Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery AN Samaha, GE Reckless, P Seeman, M Diwan, JN Nobrega, S Kapur Biological psychiatry 64 (2), 145-152, 2008 | 137 | 2008 |
Requirement of endogenous basic fibroblast growth factor for sensitization to amphetamine C Flores, AN Samaha, J Stewart The Journal of Neuroscience 20 (2), RC55, 2000 | 106 | 2000 |
Rapid delivery of nicotine promotes behavioral sensitization and alters its neurobiological impact AN Samaha, WYW Yau, P Yang, TE Robinson Biological psychiatry 57 (4), 351-360, 2005 | 101 | 2005 |
The rate of intravenous cocaine administration determines susceptibility to sensitization AN Samaha, Y Li, TE Robinson Journal of Neuroscience 22 (8), 3244-3250, 2002 | 99 | 2002 |
Revisiting long‐access versus short‐access cocaine self‐administration in rats: intermittent intake promotes addiction symptoms independent of session length F Allain, AN Samaha Addiction biology 24 (4), 641-651, 2019 | 77 | 2019 |
Sex differences in cocaine self‐administration behaviour under long access versus intermittent access conditions H Algallal, F Allain, NA Ndiaye, AN Samaha Addiction biology 25 (5), e12809, 2020 | 73 | 2020 |
Can antipsychotic treatment contribute to drug addiction in schizophrenia? AN Samaha Progress in Neuro-Psychopharmacology and Biological Psychiatry 52, 9-16, 2014 | 69 | 2014 |
High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats F Allain, K Bouayad-Gervais, AN Samaha Psychopharmacology 235, 317-328, 2018 | 68 | 2018 |
Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation F Allain, DCS Roberts, D Lévesque, AN Samaha Neuropharmacology 117, 227-237, 2017 | 67 | 2017 |
The transition to cocaine addiction: the importance of pharmacokinetics for preclinical models AB Kawa, F Allain, TE Robinson, AN Samaha Psychopharmacology 236, 1145-1157, 2019 | 66 | 2019 |
Dopamine ‘ups and downs’ in addiction revisited AN Samaha, SYS Khoo, CR Ferrario, TE Robinson Trends in Neurosciences 44 (7), 516-526, 2021 | 58 | 2021 |
The development of olfactory conditioned ejaculatory preferences in the male rat: II. Parametric manipulation of conditioning session number and duration TE Kippin, AN Samaha, V Sotiropoulos, JG Pfaus Physiology & Behavior 73 (4), 471-485, 2001 | 57 | 2001 |
Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues AM Bédard, J Maheux, D Lévesque, AN Samaha Neuropsychopharmacology 36 (6), 1248-1259, 2011 | 45 | 2011 |
Hypofunctional dopamine uptake and antipsychotic treatment-resistant schizophrenia D Amato, A Kruyer, AN Samaha, A Heinz Frontiers in psychiatry 10, 314, 2019 | 44 | 2019 |