| Discovery of macrocyclic peptides armed with a mechanism‐based warhead: isoform‐selective inhibition of human deacetylase SIRT2 J Morimoto, Y Hayashi, H Suga Angewandte Chemie 124 (14), 3479-3483, 2012 | 211 | 2012 |
| In Vitro Selection of Anti-Akt2 Thioether-Macrocyclic Peptides Leading to Isoform-Selective Inhibitors Y Hayashi, J Morimoto, H Suga ACS Chemical Biology 7 (3), 607-613, 2012 | 184 | 2012 |
| Ribosomal synthesis of bicyclic peptides via two orthogonal inter-side-chain reactions Y Sako, J Morimoto, H Murakami, H Suga Journal of the American Chemical Society 130 (23), 7232-7234, 2008 | 152 | 2008 |
| Structural basis for potent inhibition of SIRT2 deacetylase by a macrocyclic peptide inducing dynamic structural change K Yamagata, Y Goto, H Nishimasu, J Morimoto, R Ishitani, N Dohmae, ... Structure 22 (2), 345-352, 2014 | 115 | 2014 |
| Flexizymes: their evolutionary history and the origin of catalytic function J Morimoto, Y Hayashi, K Iwasaki, H Suga Accounts of chemical research 44 (12), 1359-1368, 2011 | 94 | 2011 |
| A peptoid with extended shape in water J Morimoto, Y Fukuda, D Kuroda, T Watanabe, F Yoshida, M Asada, ... Journal of the American Chemical Society 141 (37), 14612-14623, 2019 | 40 | 2019 |
| Peptide library production method, peptide library, and screening method H Suga, J Morimoto US Patent 10,195,578, 2019 | 28 | 2019 |
| Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands J Morimoto, M Sarkar, S Kenrick, T Kodadek Bioconjugate chemistry 25 (8), 1479-1491, 2014 | 26 | 2014 |
| Recognition of antigen-specific B-cell receptors from chronic lymphocytic leukemia patients by synthetic antigen surrogates M Sarkar, Y Liu, J Morimoto, H Peng, C Aquino, C Rader, N Chiorazzi, ... Chemistry & biology 21 (12), 1670-1679, 2014 | 22 | 2014 |
| Discovery of phosphorylated peripherin as a major humoral autoantigen in type 1 diabetes mellitus TM Doran, J Morimoto, S Simanski, EJ Koesema, LF Clark, K Pels, ... Cell chemical biology 23 (5), 618-628, 2016 | 19 | 2016 |
| Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues J Morimoto, T Kodadek Molecular BioSystems 11 (10), 2770-2779, 2015 | 18 | 2015 |
| Solid-Phase Synthesis of β-Peptoids with Chiral Backbone Substituents Using Reductive Amination J Morimoto, Y Fukuda, S Sando Organic letters 19 (21), 5912-5915, 2017 | 16 | 2017 |
| Targeting stereotyped B cell receptors from chronic lymphocytic leukemia patients with synthetic antigen surrogates M Sarkar, Y Liu, J Qi, H Peng, J Morimoto, C Rader, N Chiorazzi, ... Journal of Biological Chemistry 291 (14), 7558-7570, 2016 | 14 | 2016 |
| Peptoid-based reprogrammable template for cell-permeable inhibitors of protein–protein interactions Y Fukuda, M Yokomine, D Kuroda, K Tsumoto, J Morimoto, S Sando Chemical Science 12 (40), 13292-13300, 2021 | 13 | 2021 |
| Per-Residue Program of Multiple Backbone Dihedral Angles of β-Peptoids via Backbone Substitutions J Morimoto, J Kim, D Kuroda, S Nagatoishi, K Tsumoto, S Sando Journal of the American Chemical Society 142 (5), 2277-2284, 2020 | 12 | 2020 |
| Amide-to-ester substitution as a stable alternative to N-methylation for increasing membrane permeability in cyclic peptides Y Hosono, S Uchida, M Shinkai, CE Townsend, CN Kelly, MR Naylor, ... Nature Communications 14 (1), 1416, 2023 | 9 | 2023 |
| Isolation of a peptide containing D-amino acid residues that inhibits the α-helix-mediated p53–MDM2 interaction from a one-bead one-compound library J Morimoto, Y Hosono, S Sando Bioorganic & Medicinal Chemistry Letters 28 (3), 231-234, 2018 | 8 | 2018 |
| A comprehensive study on the effect of backbone stereochemistry of a cyclic hexapeptide on membrane permeability and microsomal stability Y Hosono, J Morimoto, S Sando Organic & Biomolecular Chemistry 19 (47), 10326-10331, 2021 | 7 | 2021 |
| Methyl to trifluoromethyl substitution as a strategy to increase the membrane permeability of short peptides T Ono, K Aikawa, T Okazoe, J Morimoto, S Sando Organic & Biomolecular Chemistry 19 (43), 9386-9389, 2021 | 7 | 2021 |
| A parallel permeability assay of peptides across artificial membranes and cell monolayers using a fluorogenic reaction J Morimoto, R Amano, T Ono, S Sando Organic & Biomolecular Chemistry 17 (11), 2887-2891, 2019 | 7 | 2019 |
Sando ShinsukeThe University of Tokyo確認したメール アドレス: chembio.t.u-tokyo.ac.jp
