Mark Cookson
Mark Cookson
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health
Verified email at - Homepage
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
[alpha]-synuclein locus triplication causes Parkinson's disease
AB Singleton, M Farrer, J Johnson, A Singleton, S Hague, J Kachergus, ...
Science 302 (5646), 841-842, 2003
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
DP Narendra, SM Jin, A Tanaka, DF Suen, CA Gautier, J Shen, ...
PLoS Biol 8 (1), e1000298, 2010
Genome-wide association study reveals genetic risk underlying Parkinson's disease
J Simon-Sanchez, C Schulte, JM Bras, M Sharma, JR Gibbs, D Berg, ...
Nature genetics 41 (12), 1308, 2009
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
RM Canet-Avilés, MA Wilson, DW Miller, R Ahmad, C McLendon, ...
Proceedings of the National Academy of Sciences 101 (24), 9103-9108, 2004
Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain
JR Gibbs, MP van der Brug, DG Hernandez, BJ Traynor, MA Nalls, SL Lai, ...
PLoS Genet 6 (5), e1000952, 2010
The biochemistry of Parkinson's disease
MR Cookson
Annu. Rev. Biochem. 74, 29-52, 2005
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
E Greggio, S Jain, A Kingsbury, R Bandopadhyay, P Lewis, A Kaganovich, ...
Neurobiology of disease 23 (2), 329-341, 2006
Parkin protects against the toxicity associated with mutant α-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons
L Petrucelli, C O'Farrell, PJ Lockhart, M Baptista, K Kehoe, L Vink, P Choi, ...
Neuron 36 (6), 1007-1019, 2002
An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered α-synuclein metabolism and oxidative damage
TB Sherer, R Betarbet, AK Stout, S Lund, M Baptista, AV Panov, ...
Journal of Neuroscience 22 (16), 7006-7015, 2002
Common genetic variants influence human subcortical brain structures
DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez, S Desrivičres, ...
Nature 520 (7546), 224-229, 2015
α‐Synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma
OMA El-Agnaf, SA Salem, KE Paleologou, LJ Cooper, NJ Fullwood, ...
The FASEB Journal 17 (13), 1-16, 2003
The expression of DJ‐1 (PARK7) in normal human CNS and idiopathic Parkinson’s disease
R Bandopadhyay, AE Kingsbury, MR Cookson, AR Reid, IM Evans, ...
Brain 127 (2), 420-430, 2004
Genetic variability in the regulation of gene expression in ten regions of the human brain
A Ramasamy, D Trabzuni, S Guelfi, V Varghese, C Smith, R Walker, T De, ...
Nature neuroscience 17 (10), 1418-1428, 2014
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease
MR Cookson
Nature Reviews Neuroscience 11 (12), 791-797, 2010
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ...
Nature genetics 43 (7), 699, 2011
Evidence for natural antisense transcript-mediated inhibition of microRNA function
MA Faghihi, M Zhang, J Huang, F Modarresi, MP Van der Brug, MA Nalls, ...
Genome biology 11 (5), R56, 2010
A soluble α-synuclein construct forms a dynamic tetramer
W Wang, I Perovic, J Chittuluru, A Kaganovich, LTT Nguyen, J Liao, ...
Proceedings of the National Academy of Sciences 108 (43), 17797-17802, 2011
Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability
A Beilina, M Van Der Brug, R Ahmad, S Kesavapany, DW Miller, ...
Proceedings of the National Academy of Sciences 102 (16), 5703-5708, 2005
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
KJ Thomas, MK McCoy, J Blackinton, A Beilina, M van der Brug, ...
Human molecular genetics 20 (1), 40-50, 2011
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