Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA J Sun, C Evrin, SA Samel, A Fernández-Cid, A Riera, H Kawakami, ... Nature structural & molecular biology 20 (8), 944-951, 2013 | 166 | 2013 |
A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin S Ozaki, H Kawakami, K Nakamura, N Fujikawa, W Kagawa, SY Park, ... Journal of Biological Chemistry 283 (13), 8351-8362, 2008 | 146 | 2008 |
Formation of an ATP-DnaA-specific initiation complex requires DnaA Arginine 285, a conserved motif in the AAA+ protein family H Kawakami, K Keyamura, T Katayama Journal of Biological Chemistry 280 (29), 27420-27430, 2005 | 145 | 2005 |
The DnaA Cycle in Escherichia coli: Activation, Function and Inactivation of the Initiator Protein T Katayama, K Kasho, H Kawakami Frontiers in microbiology 8, 2496, 2017 | 120 | 2017 |
Protein associations in DnaA-ATP hydrolysis mediated by the Hda-replicase clamp complex M Su'etsugu, T Shimuta, T Ishida, H Kawakami, T Katayama Journal of Biological Chemistry 280 (8), 6528-6536, 2005 | 114 | 2005 |
Cdc6-induced conformational changes in ORC bound to origin DNA revealed by cryo-electron microscopy J Sun, H Kawakami, J Zech, C Speck, B Stillman, H Li Structure 20 (3), 534-544, 2012 | 96 | 2012 |
DnaA, ORC, and Cdc6: similarity beyond the domains of life and diversity H Kawakami, T Katayama Biochemistry and cell biology 88 (1), 49-62, 2010 | 79 | 2010 |
Modes of Overinitiation, dnaA Gene Expression, and Inhibition of Cell Division in a Novel Cold-Sensitive hda Mutant of Escherichia coli K Fujimitsu, M Su'etsugu, Y Yamaguchi, K Mazda, N Fu, H Kawakami, ... Journal of bacteriology 190 (15), 5368-5381, 2008 | 59 | 2008 |
Near-atomic structural model for bacterial DNA replication initiation complex and its functional insights M Shimizu, Y Noguchi, Y Sakiyama, H Kawakami, T Katayama, S Takada Proceedings of the National Academy of Sciences 113 (50), E8021-E8030, 2016 | 54 | 2016 |
Regulatory dynamics in the ternary DnaA complex for initiation of chromosomal replication in Escherichia coli Y Sakiyama, K Kasho, Y Noguchi, H Kawakami, T Katayama Nucleic acids research 45 (21), 12354-12373, 2017 | 42 | 2017 |
The exceptionally tight affinity of DnaA for ATP/ADP requires a unique aspartic acid residue in the AAA+ sensor 1 motif H Kawakami, S Ozaki, S Suzuki, K Nakamura, T Senriuchi, M Su'etsugu, ... Molecular microbiology 62 (5), 1310-1324, 2006 | 42 | 2006 |
DNA replication‐coupled inactivation of DnaA protein in vitro: a role for DnaA arginine‐334 of the AAA+ Box VIII motif in ATP hydrolysis M Su'Etsugu, H Kawakami, K Kurokawa, T Kubota, M Takata, T Katayama Molecular Microbiology 40 (2), 376-386, 2001 | 37 | 2001 |
The Arg fingers of key DnaA protomers are oriented inward within the replication origin oriC and stimulate DnaA subcomplexes in the initiation complex Y Noguchi, Y Sakiyama, H Kawakami, T Katayama Journal of Biological Chemistry 290 (33), 20295-20312, 2015 | 36 | 2015 |
Specific binding of eukaryotic ORC to DNA replication origins depends on highly conserved basic residues H Kawakami, E Ohashi, S Kanamoto, T Tsurimoto, T Katayama Scientific reports 5, 14929, 2015 | 36 | 2015 |
A replicase clamp-binding dynamin-like protein promotes colocalization of nascent DNA strands and equipartitioning of chromosomes in E. coli S Ozaki, Y Matsuda, K Keyamura, H Kawakami, Y Noguchi, K Kasho, ... Cell Reports 4 (5), 985-995, 2013 | 35 | 2013 |
An isolated Hda–clamp complex is functional in the regulatory inactivation of DnaA and DNA replication H Kawakami, M Su’etsugu, T Katayama Journal of structural biology 156 (1), 220-229, 2006 | 34 | 2006 |
Arrest of cell division and nucleoid partition by genetic alterations in the sliding clamp of the replicase and in DnaA H Kawakami, T Iwura, M Takata, K Sekimizu, S Hiraga, T Katayama Molecular Genetics and Genomics 266, 167-179, 2001 | 26 | 2001 |
Single-stranded DNA recruitment mechanism in replication origin unwinding by DnaA initiator protein and HU, an evolutionary ubiquitous nucleoid protein R Yoshida, S Ozaki, H Kawakami, T Katayama Nucleic acids research 51 (12), 6286-6306, 2023 | 15 | 2023 |
Specific basic patch‐dependent multimerization of Saccharomyces cerevisiae ORC on single‐stranded DNA promotes ATP hydrolysis H Kawakami, R Muraoka, E Ohashi, K Kawabata, S Kanamoto, ... Genes to Cells 24 (9), 608-618, 2019 | 2 | 2019 |
Rapid Purification and Characterization of Mutant Origin Recognition Complexes in Saccharomyces cerevisiae H Kawakami, E Ohashi, T Tsurimoto, T Katayama Frontiers in Microbiology 7, 521, 2016 | 1 | 2016 |