フォロー
Michael Crabtree
Michael Crabtree
確認したメール アドレス: bioch.ox.ac.uk
タイトル
引用先
引用先
Insights into coupled folding and binding mechanisms from kinetic studies
SL Shammas, MD Crabtree, L Dahal, BIM Wicky, J Clarke
Journal of Biological Chemistry 291 (13), 6689-6695, 2016
1542016
Protein-peptide association kinetics beyond the seconds timescale from atomistic simulations
F Paul, C Wehmeyer, ET Abualrous, H Wu, MD Crabtree, J Schöneberg, ...
Nature Communications 8, 1095, 2017
1422017
Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein: Target Affinity by Altering the Lifetime of the Bound Complex
MD Crabtree, W Borcherds, A Poosapati, SL Shammas, GW Daughdrill, ...
Biochemistry 56 (18), 2379-2384, 2017
462017
Folding and binding pathways of BH3-only proteins are encoded within their intrinsically disordered sequence, not templated by partner proteins
MD Crabtree, CATF Mendonça, QR Bubb, J Clarke
Journal of Biological Chemistry 293 (25), 9718-9723, 2018
382018
Bitopic binding mode of an M1 muscarinic acetylcholine receptor agonist associated with adverse clinical trial outcomes
SJ Bradley, C Molloy, C Bundgaard, AJ Mogg, KJ Thompson, L Dwomoh, ...
Molecular pharmacology 93 (6), 645-656, 2018
282018
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu
Protein Engineering, Design and Selection 29 (9), 339-346, 2016
232016
123I-iododexetimide preferentially binds to the muscarinic receptor subtype M1 in vivo
G Bakker, WA Vingerhoets, JP van Wieringen, K de Bruin, J Eersels, ...
J Nucl Med 56 (2), 317-322, 2015
192015
Repulsive electrostatic interactions modulate dense and dilute phase properties of biomolecular condensates
MD Crabtree, J Holland, PS Kompella, L Babl, NN Turner, AJ Baldwin, ...
bioRxiv, 2020
122020
In vitro pharmacological characterization and in vivo validation of LSN3172176 a novel M1 selective muscarinic receptor agonist tracer molecule for positron emission tomography …
AJ Mogg, T Eessalu, M Johnson, R Wright, HE Sanger, H Xiou, ...
The Journal of pharmacology and experimental therapeutics, 2018
122018
Thermodynamic Mapping of Effector Protein Interfaces with RalA and RalB
LJ Campbell, M Peppa, MD Crabtree, A Shafiq, NF McGough, HR Mott, ...
Biochemistry 54 (6), 1380-1389, 2015
62015
Stopped-Flow Kinetic Techniques for Studying Binding Reactions of Intrinsically Disordered Proteins.
MD Crabtree, SL Shammas
Methods in enzymology 611, 423-457, 2018
52018
In Vitro Transition Temperature Measurement of Phase-Separating Proteins by Microscopy
J Holland, MD Crabtree, TJ Nott
Intrinsically Disordered Proteins, 703-714, 2020
32020
Ion binding with charge inversion combined with screening modulates DEAD box helicase phase transitions
MD Crabtree, J Holland, AS Pillai, PS Kompella, L Babl, NN Turner, ...
Cell Reports 42 (11), 2023
12023
Cellular Droplets Newly discovered liquid dynamics within the cytoplasm and nucleus play critical roles in cell biology
M Crabtree, T Nott
SCIENTIST 32 (12), 28-35, 2018
2018
Probing Order within Intrinsically Disordered Proteins
MD Crabtree
University of Cambridge, 2017
2017
What Encodes Coupled Folding and Binding Reactions: IDPS or Partner Proteins?
MD Crabtree, CATF Mendonca, Q Bubb, SL Shammas, J Clarke
Biophysical Journal 112 (3), 481a, 2017
2017
IDPs that Fold Upon Binding: What is the Role of the Partner Protein?
SL Shammas, J Rogers, M Crabtree, J Clarke
Biophysical Journal 108 (2), 228a, 2015
2015
Better cloning through expression
MD Crabtree
Science 346 (6216), 1477-1477, 2014
2014
Handle with Care: An Unusual Butterfly Journey
MD Crabtree
Science 346 (6214), 1175, 2014
2014
What Makes You YOU?
MD Crabtree
Science 346 (6214), 1178, 2014
2014
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論文 1–20