Memory CD8 T cell responses exceeding a large but definable threshold provide long-term immunity to malaria NW Schmidt, RL Podyminogin, NS Butler, VP Badovinac, BJ Tucker, ... Proceedings of the National Academy of Sciences 105 (37), 14017-14022, 2008 | 301 | 2008 |
Composition of the gut microbiota modulates the severity of malaria NF Villarino, GR LeCleir, JE Denny, SP Dearth, CL Harding, SS Sloan, ... Proceedings of the National Academy of Sciences 113 (8), 2235-2240, 2016 | 285 | 2016 |
Superior antimalarial immunity after vaccination with late liver stage-arresting genetically attenuated parasites NS Butler, NW Schmidt, AM Vaughan, AS Aly, SHI Kappe, JT Harty Cell host & microbe 9 (6), 451-462, 2011 | 266 | 2011 |
Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites NW Schmidt, NS Butler, VP Badovinac, JT Harty PLoS pathogens 6 (7), e1000998, 2010 | 218 | 2010 |
Overview: Systemic Inflammatory Response Derived From Lung Injury Caused by SARS-CoV-2 Infection Explains Severe Outcomes in COVID-19 RB Polidoro, RS Hagan, R de Santis Santiago, NW Schmidt Frontiers in Immunology 11, 1626, 2020 | 194 | 2020 |
Bruton’s tyrosine kinase is required for TLR-induced IL-10 production NW Schmidt, VT Thieu, BA Mann, ANN Ahyi, MH Kaplan The Journal of Immunology 177 (10), 7203-7210, 2006 | 123 | 2006 |
Distinct requirements for the naturally occurring splice forms Stat4α and Stat4β in IL‐12 responses T Hoey, S Zhang, N Schmidt, Q Yu, S Ramchandani, X Xu, LK Naeger, ... The EMBO journal 22 (16), 4237-4248, 2003 | 122 | 2003 |
Platelet-derived CD154 enables T-cell priming and protection against Listeria monocytogenes challenge BD Elzey, NW Schmidt, SA Crist, TP Kresowik, JT Harty, B Nieswandt, ... Blood, The Journal of the American Society of Hematology 111 (7), 3684-3691, 2008 | 107 | 2008 |
Differential effector pathways regulate memory CD8 T cell immunity against Plasmodium berghei versus P. yoelii sporozoites NS Butler, NW Schmidt, JT Harty The Journal of Immunology 184 (5), 2528-2538, 2010 | 101 | 2010 |
IL-4 is a critical determinant in the generation of allergic inflammation initiated by a constitutively active Stat6 S Sehra, HA Bruns, ANN Ahyi, ET Nguyen, NW Schmidt, EG Michels, ... The Journal of Immunology 180 (5), 3551-3559, 2008 | 67 | 2008 |
Functional characteristics of the gut microbiome in C57BL/6 mice differentially susceptible to Plasmodium yoelii J Stough, SP Dearth, JE Denny, GR LeCleir, NW Schmidt, SR Campagna, ... Frontiers in microbiology 7, 1520, 2016 | 60 | 2016 |
Plasmodium–host interactions directly influence the threshold of memory CD8 T cells required for protective immunity NW Schmidt, NS Butler, JT Harty The Journal of Immunology 186 (10), 5873-5884, 2011 | 54 | 2011 |
Malaria and the microbiome: a systematic review MM Ippolito, JE Denny, C Langelier, CL Sears, NW Schmidt Clinical Infectious Diseases 67 (12), 1831-1839, 2018 | 53 | 2018 |
Local and long-distance calling: conversations between the gut microbiota and intra-and extra-gastrointestinal tract infections JE Denny, WL Powell, NW Schmidt Frontiers in Cellular and Infection Microbiology 6, 41, 2016 | 32 | 2016 |
Cutting edge: attrition of Plasmodium-specific memory CD8 T cells results in decreased protection that is rescued by booster immunization NW Schmidt, JT Harty The Journal of Immunology 186 (7), 3836-3840, 2011 | 32 | 2011 |
Differential Sensitivity to Plasmodium yoelii Infection in C57BL/6 Mice Impacts Gut-Liver Axis Homeostasis JE Denny, JB Powers, HF Castro, J Zhang, S Joshi-Barve, SR Campagna, ... Scientific reports 9 (1), 3472, 2019 | 30 | 2019 |
CD8 T cell immunity to Plasmodium permits generation of protective antibodies after repeated sporozoite challenge NW Schmidt, NS Butler, JT Harty Vaccine 27 (44), 6103-6106, 2009 | 24 | 2009 |
Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection RK Mandal, JE Denny, R Namazzi, RO Opoka, D Datta, CC John, ... Cell reports 35 (6), 2021 | 20 | 2021 |
CD8+ T cell responses to Plasmodium and intracellular parasites NF Villarion, NW Schmidt Current Immunology Reviews 9, 169-178, 2013 | 20 | 2013 |
Gut microbiota composition modulates the magnitude and quality of germinal centers during Plasmodium infections ML Waide, R Polidoro, WL Powell, JE Denny, J Kos, DA Tieri, CT Watson, ... Cell reports 33 (11), 2020 | 19 | 2020 |