| Synthesis and structure–activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2, 5-dione structure Y Yamazaki, K Tanaka, B Nicholson, G Deyanat-Yazdi, B Potts, T Yoshida, ... Journal of medicinal chemistry 55 (3), 1056-1071, 2012 | 122 | 2012 |
| Inhibition of microtubule assembly by a complex of actin and antitumor macrolide aplyronine A M Kita, Y Hirayama, K Yoneda, K Yamagishi, T Chinen, T Usui, E Sumiya, ... Journal of the American Chemical Society 135 (48), 18089-18095, 2013 | 71 | 2013 |
| Syntheses and Biological Evaluation of Irciniastatin A and the C1− C2 Alkyne Analogue T Watanabe, T Imaizumi, T Chinen, Y Nagumo, M Shibuya, T Usui, ... Organic letters 12 (5), 1040-1043, 2010 | 62 | 2010 |
| The γ-tubulin-specific inhibitor gatastatin reveals temporal requirements of microtubule nucleation during the cell cycle T Chinen, P Liu, S Shioda, J Pagel, B Cerikan, T Lin, O Gruss, Y Hayashi, ... Nature communications 6 (1), 8722, 2015 | 59 | 2015 |
| Synthesis and structure–activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents Y Yamazaki, M Sumikura, Y Masuda, Y Hayashi, H Yasui, Y Kiso, ... Bioorganic & medicinal chemistry 20 (14), 4279-4289, 2012 | 53 | 2012 |
| MOZART1 and γ-tubulin complex receptors are both required to turn γ-TuSC into an active microtubule nucleation template T Lin, A Neuner, D Flemming, P Liu, T Chinen, U Jäkle, R Arkowitz, ... Journal of Cell Biology 215 (6), 823-840, 2016 | 51 | 2016 |
| Development of a new benzophenone–diketopiperazine-type potent antimicrotubule agent possessing a 2-pyridine structure Y Hayashi, H Takeno, T Chinen, K Muguruma, K Okuyama, A Taguchi, ... ACS Medicinal Chemistry Letters 5 (10), 1094-1098, 2014 | 44 | 2014 |
| Irciniastatin A induces JNK activation that is involved in caspase-8-dependent apoptosis via the mitochondrial pathway T Chinen, Y Nagumo, T Watanabe, T Imaizumi, M Shibuya, T Kataoka, ... Toxicology letters 199 (3), 341-346, 2010 | 41 | 2010 |
| NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells T Chinen, S Yamamoto, Y Takeda, K Watanabe, K Kuroki, K Hashimoto, ... The EMBO journal 39 (2), e102378, 2020 | 36 | 2020 |
| Terpendole E and its Derivative Inhibit STLC‐and GSK‐1‐Resistant Eg5 Y Tarui, T Chinen, Y Nagumo, T Motoyama, T Hayashi, H Hirota, M Muroi, ... ChemBioChem 15 (7), 934-938, 2014 | 36 | 2014 |
| Robust classification of cell cycle phase and biological feature extraction by image-based deep learning Y Nagao, M Sakamoto, T Chinen, Y Okada, D Takao Molecular biology of the cell 31 (13), 1346-1354, 2020 | 33 | 2020 |
| Total synthesis and biological evaluation of irciniastatin A (aka psymberin) and irciniastatin B S Uesugi, T Watanabe, T Imaizumi, Y Ota, K Yoshida, H Ebisu, T Chinen, ... The Journal of Organic Chemistry 80 (24), 12333-12350, 2015 | 31 | 2015 |
| Stress-dependent cell stiffening by tardigrade tolerance proteins that reversibly form a filamentous network and gel A Tanaka, T Nakano, K Watanabe, K Masuda, G Honda, S Kamata, ... PLoS Biology 20 (9), e3001780, 2022 | 28 | 2022 |
| Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly T Chinen, K Yamazaki, K Hashimoto, K Fujii, K Watanabe, Y Takeda, ... Journal of Cell Biology 220 (2), e202006085, 2021 | 28 | 2021 |
| Design, synthesis, and biological evaluation of the analogues of glaziovianin A, a potent antitumor isoflavone I Hayakawa, A Ikedo, T Chinen, T Usui, H Kigoshi Bioorganic & medicinal chemistry 20 (19), 5745-5756, 2012 | 24 | 2012 |
| Glaziovianin A Prevents Endosome Maturation via Inhibiting Microtubule Dynamics T Chinen, S Kazami, Y Nagumo, I Hayakawa, A Ikedo, M Takagi, ... ACS chemical biology 8 (5), 884-889, 2013 | 22 | 2013 |
| Construction of multidrug-sensitive yeast with high sporulation efficiency T Chinen, Y Ota, Y Nagumo, H Masumoto, T Usui Bioscience, biotechnology, and biochemistry 75 (8), 1588-1593, 2011 | 22 | 2011 |
| Eudistomin C, an antitumor and antiviral natural product, targets 40S ribosome and inhibits protein translation Y Ota, T Chinen, K Yoshida, S Kudo, Y Nagumo, Y Shiwa, R Yamada, ... ChemBioChem 17 (17), 1616-1620, 2016 | 18 | 2016 |
| Fusaramin, an antimitochondrial compound produced by Fusarium sp., discovered using multidrug-sensitive Saccharomyces cerevisiae K Sakai, Y Unten, M Iwatsuki, H Matsuo, W Fukasawa, T Hirose, T Chinen, ... The Journal of Antibiotics 72 (9), 645-652, 2019 | 17 | 2019 |
| Centrosomal and non-centrosomal functions emerged through eliminating centrosomes Y Takeda, K Kuroki, T Chinen, D Kitagawa Cell structure and function 45 (1), 57-64, 2020 | 12 | 2020 |
