Structure of the trypanosome cyanide-insensitive alternative oxidase T Shiba, Y Kido, K Sakamoto, DK Inaoka, C Tsuge, R Tatsumi, ... Proceedings of the National Academy of Sciences 110 (12), 4580-4585, 2013 | 210 | 2013 |
Two Plasmodium 6‐Cys family‐related proteins have distinct and critical roles in liver‐stage development T Annoura, BCL van Schaijk, IHJ Ploemen, M Sajid, J Lin, MW Vos, ... The FASEB Journal 28 (5), 2158-2170, 2014 | 104 | 2014 |
Structural insights into the molecular design of flutolanil derivatives targeted for fumarate respiration of parasite mitochondria DK Inaoka, T Shiba, D Sato, EO Balogun, T Sasaki, M Nagahama, M Oda, ... International journal of molecular sciences 16 (7), 15287-15308, 2015 | 80 | 2015 |
Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum Y Araki, T Awakawa, M Matsuzaki, R Cho, Y Matsuda, S Hoshino, ... Proceedings of the National Academy of Sciences 116 (17), 8269-8274, 2019 | 78 | 2019 |
Characterization of the dihydroorotate dehydrogenase as a soluble fumarate reductase in Trypanosoma cruzi E Takashima, DK Inaoka, A Osanai, T Nara, M Odaka, T Aoki, K Inaka, ... Molecular and biochemical parasitology 122 (2), 189-200, 2002 | 64 | 2002 |
Structures of Trypanosoma cruzi Dihydroorotate Dehydrogenase Complexed with Substrates and Products: Atomic Resolution Insights into Mechanisms of … DK Inaoka, K Sakamoto, H Shimizu, T Shiba, G Kurisu, T Nara, T Aoki, ... Biochemistry 47 (41), 10881-10891, 2008 | 58 | 2008 |
Biochemical studies of membrane bound Plasmodium falciparum mitochondrial L-malate: quinone oxidoreductase, a potential drug target ED Hartuti, DK Inaoka, K Komatsuya, Y Miyazaki, RJ Miller, W Xinying, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (3), 191-200, 2018 | 48 | 2018 |
Crystal structure of mitochondrial quinol–fumarate reductase from the parasitic nematode Ascaris suum H Shimizu, A Osanai, K Sakamoto, DK Inaoka, T Shiba, S Harada, K Kita The journal of biochemistry 151 (6), 589-592, 2012 | 46 | 2012 |
Pharmacophore modeling for anti-chagas drug design using the fragment molecular orbital method R Yoshino, N Yasuo, DK Inaoka, Y Hagiwara, K Ohno, M Orita, M Inoue, ... PLoS One 10 (5), e0125829, 2015 | 44 | 2015 |
Selective cytotoxicity of dihydroorotate dehydrogenase inhibitors to human cancer cells under hypoxia and nutrient-deprived conditions Y Miyazaki, DK Inaoka, T Shiba, H Saimoto, T Sakura, E Amalia, Y Kido, ... Frontiers in pharmacology 9, 997, 2018 | 40 | 2018 |
5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro Y Sakurai, MMN Tun, Y Kurosaki, T Sakura, DK Inaoka, K Fujine, K Kita, ... Biochemical and biophysical research communications 545, 203-207, 2021 | 38 | 2021 |
Diversity of parasite complex II S Harada, DK Inaoka, J Ohmori, K Kita Biochimica et Biophysica Acta (BBA)-Bioenergetics 1827 (5), 658-667, 2013 | 36 | 2013 |
Conjugates of 2, 4-dihydroxybenzoate and salicylhydroxamate and lipocations display potent antiparasite effects by efficiently targeting the Trypanosoma brucei and Trypanosoma … FJ Fueyo Gonzalez, GU Ebiloma, C Izquierdo Garcia, V Bruggeman, ... Journal of medicinal chemistry 60 (4), 1509-1522, 2017 | 33 | 2017 |
Identification of Plasmodium falciparum Mitochondrial Malate: Quinone Oxidoreductase Inhibitors from the Pathogen Box X Wang, Y Miyazaki, DK Inaoka, ED Hartuti, YI Watanabe, T Shiba, ... Genes 10 (6), 471, 2019 | 29 | 2019 |
Inhibition of trypanosome alternative oxidase without its N-terminal mitochondrial targeting signal (ΔMTS-TAO) by cationic and non-cationic 4-hydroxybenzoate and 4 … GU Ebiloma, TD Ayuga, EO Balogun, LA Gil, A Donachie, M Kaiser, ... European journal of medicinal chemistry 150, 385-402, 2018 | 29 | 2018 |
Re-identification of the ascofuranone-producing fungus Ascochyta viciae as Acremonium sclerotigenum Y Hijikawa, M Matsuzaki, S Suzuki, DK Inaoka, R Tatsumi, Y Kido, K Kita The Journal of antibiotics 70 (3), 304-307, 2017 | 29 | 2017 |
Crystallization and preliminary crystallographic analysis of cyanide-insensitive alternative oxidase from Trypanosoma brucei brucei Y Kido, T Shiba, DK Inaoka, K Sakamoto, T Nara, T Aoki, T Honma, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 28 | 2010 |
Probing the ubiquinol-binding site of recombinant Sauromatum guttatum alternative oxidase expressed in E. coli membranes through site-directed mutagenesis L Young, B May, A Pendlebury-Watt, J Shearman, C Elliott, MS Albury, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1837 (7), 1219-1225, 2014 | 27 | 2014 |
In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease R Yoshino, N Yasuo, Y Hagiwara, T Ishida, DK Inaoka, Y Amano, ... Scientific Reports 7 (1), 6666, 2017 | 26 | 2017 |
Functional importance of crenarchaea-specific extra-loop revealed by an X-ray structure of a heterotetrameric crenarchaeal splicing endonuclease S Yoshinari, T Shiba, DK Inaoka, T Itoh, G Kurisu, S Harada, K Kita, ... Nucleic acids research 37 (14), 4787-4798, 2009 | 25 | 2009 |