The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors DY Lin, Y Tanaka, M Iwasaki, AG Gittis, HP Su, B Mikami, T Okazaki, ... Proceedings of the National Academy of Sciences 105 (8), 3011-3016, 2008 | 524 | 2008 |
Interaction of CED-6/GULP, an adapter protein involved in engulfment of apoptotic cells with CED-1 and CD91/low density lipoprotein receptor-related protein (LRP) HP Su, K Nakada-Tsukui, AC Tosello-Trampont, Y Li, G Bu, PM Henson, ... Journal of Biological Chemistry 277 (14), 11772-11779, 2002 | 284 | 2002 |
Selective CD4+ T cell help for antibody responses to a large viral pathogen: deterministic linkage of specificities A Sette, M Moutaftsi, J Moyron-Quiroz, MM McCausland, DH Davies, ... Immunity 28 (6), 847-858, 2008 | 213 | 2008 |
Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors HP Su, Y Yan, GS Prasad, RF Smith, CL Daniels, PD Abeywickrema, ... Journal of virology 84 (15), 7625-7633, 2010 | 115 | 2010 |
Redundancy and plasticity of neutralizing antibody responses are cornerstone attributes of the human immune response to the smallpox vaccine MREI Benhnia, MM McCausland, HP Su, K Singh, J Hoffmann, DH Davies, ... Journal of virology 82 (7), 3751-3768, 2008 | 101 | 2008 |
Essential role for the C-terminal noncatalytic region of SHIP in FcγRIIB1-mediated inhibitory signaling MJ Aman, SF Walk, ME March, HP Su, DJ Carver, KS Ravichandran Molecular and cellular biology 20 (10), 3576-3589, 2000 | 86 | 2000 |
Discovery of 1-Amino-5H-pyrido[4,3-b]indol-4-carboxamide Inhibitors of Janus Kinase 2 (JAK2) for the Treatment of Myeloproliferative Disorders J Lim, B Taoka, RD Otte, K Spencer, CJ Dinsmore, MD Altman, G Chan, ... Journal of medicinal chemistry 54 (20), 7334-7349, 2011 | 81 | 2011 |
The 1.51-Å structure of the poxvirus L1 protein, a target of potent neutralizing antibodies HP Su, SC Garman, TJ Allison, C Fogg, B Moss, DN Garboczi Proceedings of the National Academy of Sciences 102 (12), 4240-4245, 2005 | 80 | 2005 |
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein A Tang, Z Chen, KS Cox, HP Su, C Callahan, A Fridman, L Zhang, ... Nature communications 10 (1), 4153, 2019 | 78 | 2019 |
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain SJ Stachel, JM Sanders, DA Henze, MT Rudd, HP Su, Y Li, KK Nanda, ... Journal of Medicinal Chemistry 57 (13), 5800-5816, 2014 | 77 | 2014 |
The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms AK Saxena, K Singh, HP Su, MM Klein, AW Stowers, AJ Saul, CA Long, ... Nature structural & molecular biology 13 (1), 90-91, 2006 | 75 | 2006 |
Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication D Camerini, HP Su, G Gamez-Torre, ML Johnson, JA Zack, ISY Chen Journal of virology 74 (7), 3196-3204, 2000 | 64 | 2000 |
Human immunodeficiency virus type 1 pathogenesis in SCID-hu mice correlates with syncytium-inducing phenotype and viral replication D Camerini, HP Su, G Gamez-Torre, ML Johnson, JA Zack, ISY Chen Journal of virology 74 (7), 3196-3204, 2000 | 64 | 2000 |
The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure MM Klein, AG Gittis, HP Su, MO Makobongo, JM Moore, S Singh, ... PLoS pathogens 4 (9), e1000147, 2008 | 62 | 2008 |
Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells HP Su, E Brugnera, W Van Criekinge, E Smits, M Hengartner, T Bogaert, ... Journal of Biological Chemistry 275 (13), 9542-9549, 2000 | 57 | 2000 |
Structural basis for the binding of the neutralizing antibody, 7D11, to the poxvirus L1 protein HP Su, JW Golden, AG Gittis, JW Hooper, DN Garboczi Virology 368 (2), 331-341, 2007 | 56 | 2007 |
Structural characterization of nonactive site, TrkA-selective kinase inhibitors HP Su, K Rickert, C Burlein, K Narayan, M Bukhtiyarova, DM Hurzy, ... Proceedings of the National Academy of Sciences 114 (3), E297-E306, 2017 | 47 | 2017 |
The structure of the poxvirus A33 protein reveals a dimer of unique C-type lectin-like domains HP Su, K Singh, AG Gittis, DN Garboczi Journal of virology 84 (5), 2502-2510, 2010 | 45 | 2010 |
Design and synthesis of piperazine sulfonamide cores leading to highly potent HIV-1 protease inhibitors CJ Bungard, PD Williams, J Schulz, CM Wiscount, MK Holloway, ... ACS medicinal chemistry letters 8 (12), 1292-1297, 2017 | 41 | 2017 |
The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-glucose K Singh, AG Gittis, RK Gitti, SA Ostazeski, HP Su, DN Garboczi Journal of virology 90 (10), 5020-5030, 2016 | 41 | 2016 |