フォロー
Peter Gennemark
Peter Gennemark
Researcher at AstraZeneca
確認したメール アドレス: astrazeneca.com
タイトル
引用先
引用先
Integrative model of the response of yeast to osmotic shock
E Klipp, B Nordlander, R Krüger, P Gennemark, S Hohmann
Nature biotechnology 23 (8), 975-982, 2005
5332005
Models from experiments: combinatorial drug perturbations of cancer cells
S Nelander, W Wang, B Nilsson, QB She, C Pratilas, N Rosen, ...
Molecular systems biology 4 (1), 216, 2008
2102008
Network modeling of the transcriptional effects of copy number aberrations in glioblastoma
R Jörnsten, T Abenius, T Kling, L Schmidt, E Johansson, TEM Nordling, ...
Molecular systems biology 7 (1), 486, 2011
1092011
Structural and functional characterization of a specific antidote for ticagrelor
A Buchanan, P Newton, S Pehrsson, T Inghardt, T Antonsson, ...
Blood, The Journal of the American Society of Hematology 125 (22), 3484-3490, 2015
972015
An oral antisense oligonucleotide for PCSK9 inhibition
P Gennemark, K Walter, N Clemmensen, D Rekić, CAM Nilsson, ...
Science Translational Medicine 13 (593), eabe9117, 2021
882021
Efficient algorithms for ordinary differential equation model identification of biological systems
P Gennemark, D Wedelin
IET Systems Biology 1 (2), 120-129, 2007
682007
Unlock the thermogenic potential of adipose tissue: pharmacological modulation and implications for treatment of diabetes and obesity
XR Peng, P Gennemark, G O’Mahony, S Bartesaghi
Frontiers in endocrinology 6, 174, 2015
662015
Benchmarks for identification of ordinary differential equations from time series data
P Gennemark, D Wedelin
Bioinformatics 25 (6), 780-786, 2009
642009
PPARγ and PPARα synergize to induce robust browning of white fat in vivo
T Kroon, M Harms, S Maurer, L Bonnet, I Alexandersson, A Lindblom, ...
Molecular metabolism 36, 100964, 2020
582020
Discovery of (3-(4-(2-oxa-6-azaspiro [3.3] heptan-6-ylmethyl) phenoxy) azetidin-1-yl)(5-(4-methoxyphenyl)-1, 3, 4-oxadiazol-2-yl) methanone (AZD1979), a melanin concentrating …
A Johansson, C Lofberg, M Antonsson, S von Unge, MA Hayes, R Judkins, ...
Journal of Medicinal Chemistry 59 (6), 2497-2511, 2016
552016
A simple mathematical model of adaptation to high osmolarity in yeast
P Gennemark, B Nordlander, S Hohmann, D Wedelin
In silico biology 6 (3), 193-214, 2006
542006
Hemostatic effects of the ticagrelor antidote MEDI2452 in pigs treated with ticagrelor on a background of aspirin
S Pehrsson, KJ Johansson, A Janefeldt, AS Sandinge, S Maqbool, ...
Journal of Thrombosis and Haemostasis 15 (6), 1213-1222, 2017
282017
Distribution and biotransformation of therapeutic antisense oligonucleotides and conjugates
L Weidolf, A Björkbom, A Dahlen, M Elebring, P Gennemark, M Hölttä, ...
Drug discovery today 26 (10), 2244-2258, 2021
232021
A modeling approach for compounds affecting body composition
P Gennemark, R Jansson-Löfmark, G Hyberg, M Wigstrand, D Kakol-Palm, ...
Journal of pharmacokinetics and pharmacodynamics 40, 651-667, 2013
212013
Requirements for multi-level systems pharmacology models to reach end-usage: the case of type 2 diabetes
E Nyman, YJW Rozendaal, G Helmlinger, B Hamrén, MC Kjellsson, ...
Interface focus 6 (2), 20150075, 2016
202016
Formal representation of the high osmolarity glycerol pathway in yeast
C Kühn, KVS Prasad, E Klipp, P Gennemark
Genome Informatics 2009: Genome Informatics Series Vol. 22, 69-83, 2010
182010
Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes
E Nyman, S Bartesaghi, R Melin Rydfalk, S Eng, C Pollard, P Gennemark, ...
NPJ systems biology and applications 3 (1), 29, 2017
162017
Effects of a novel potent melanin‐concentrating hormone receptor 1 antagonist, AZD1979, on body weight homeostasis in mice and dogs
K Ploj, L Benthem, D Kakol‐Palm, P Gennemark, L Andersson, M Bjursell, ...
British Journal of Pharmacology 173 (18), 2739-2751, 2016
162016
Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios
T Herrgårdh, VI Madai, JD Kelleher, R Magnusson, M Gustafsson, ...
NeuroImage: Clinical 31, 102694, 2021
152021
Quantifying and communicating uncertainty in preclinical human dose‐prediction
M Sundqvist, A Lundahl, MB Någård, U Bredberg, P Gennemark
CPT: pharmacometrics & systems pharmacology 4 (4), 243-254, 2015
152015
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