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Toshiaki Okuno
Toshiaki Okuno
Verified email at juntendo.ac.jp
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Year
G2A is a proton-sensing G-protein-coupled receptor antagonized by lysophosphatidylcholine
N Murakami, T Yokomizo, T Okuno, T Shimizu
Journal of Biological Chemistry 279 (41), 42484-42491, 2004
2702004
12(S)-hydroxyheptadeca-5Z, 8E, 10E–trienoic acid is a natural ligand for leukotriene B4 receptor 2
T Okuno, Y Iizuka, H Okazaki, T Yokomizo, R Taguchi, T Shimizu
The Journal of experimental medicine 205 (4), 759-766, 2008
2172008
Delphilin: a novel PDZ and formin homology domain-containing protein that synaptically colocalizes and interacts with glutamate receptor δ2 subunit
Y Miyagi, T Yamashita, M Fukaya, T Sonoda, T Okuno, K Yamada, ...
Journal of Neuroscience 22 (3), 803-814, 2002
1352002
12-Hydroxyheptadecatrienoic acid promotes epidermal wound healing by accelerating keratinocyte migration via the BLT2 receptor
M Liu, K Saeki, T Matsunobu, T Okuno, T Koga, Y Sugimoto, C Yokoyama, ...
Journal of Experimental Medicine 211 (6), 1063-1078, 2014
1222014
The role of leukotrienes as potential therapeutic targets in allergic disorders
A Jo-Watanabe, T Okuno, T Yokomizo
International journal of molecular sciences 20 (14), 3580, 2019
1162019
Protective role of the leukotriene B4 receptor BLT2 in murine inflammatory colitis
Y Iizuka, T Okuno, K Saeki, H Uozaki, S Okada, T Misaka, T Sato, H Toh, ...
The FASEB Journal 24 (12), 4678-4690, 2010
1132010
Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1
T Hori, T Okuno, K Hirata, K Yamashita, Y Kawano, M Yamamoto, M Hato, ...
Nature chemical biology 14 (3), 262-269, 2018
832018
Determination of double bond positions in polyunsaturated fatty acids using the photochemical Paterno-Buchi reaction with acetone and tandem mass spectrometry
RC Murphy, T Okuno, CA Johnson, RM Barkley
Analytical chemistry 89 (16), 8545-8553, 2017
792017
Leukotriene B4 receptor and the function of its helix 8
T Okuno, T Yokomizo, T Hori, M Miyano, T Shimizu
Journal of Biological Chemistry 280 (37), 32049-32052, 2005
752005
Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2
S Iwamoto, T Koga, M Ohba, T Okuno, M Koike, A Murakami, A Matsuda, ...
Scientific reports 7 (1), 13267, 2017
642017
Thromboxane A synthase-independent production of 12-hydroxyheptadecatrienoic acid, a BLT2 ligand [S]
T Matsunobu, T Okuno, C Yokoyama, T Yokomizo
Journal of lipid research 54 (11), 2979-2987, 2013
642013
Helix 8 of the leukotriene B4 receptor is required for the conformational change to the low affinity state after G-protein activation
T Okuno, H Ago, K Terawaki, M Miyano, T Shimizu, T Yokomizo
Journal of Biological Chemistry 278 (42), 41500-41509, 2003
612003
Leukotriene B4 receptor BLT2 negatively regulates allergic airway eosinophilia
Y Matsunaga, S Fukuyama, T Okuno, F Sasaki, T Matsunobu, Y Asai, ...
The FASEB Journal 27 (8), 3306-3314, 2013
552013
Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins
Y Ishii, K Saeki, M Liu, F Sasaki, T Koga, K Kitajima, C Meno, T Okuno, ...
The FASEB Journal 30 (2), 933-947, 2016
532016
Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models
F Sasaki, T Koga, M Ohba, K Saeki, T Okuno, K Ishikawa, T Nakama, ...
JCI insight 3 (18), 2018
462018
Chemical study on hapalosin, a cyclic depsipeptide possessing multidrug resistance reversing activities: Synthesis, structure and biological activity
T Okuno, K Ohmori, S Nishiyama, S Yamamura, K Nakamura, KN Houk, ...
Tetrahedron 52 (47), 14723-14734, 1996
461996
From the cover: prolonged exposure to volatile anesthetic isoflurane worsens the outcome of polymicrobial abdominal sepsis
S Koutsogiannaki, MM Schaefers, T Okuno, M Ohba, T Yokomizo, ...
Toxicological Sciences 156 (2), 402-411, 2017
442017
Identification of the intracellular region of the leukotriene B4 receptor type 1 that is specifically involved in Gi activation
K Kuniyeda, T Okuno, K Terawaki, M Miyano, T Yokomizo, T Shimizu
Journal of biological chemistry 282 (6), 3998-4006, 2007
442007
TTN oxidation of mixed halogenated phenols: Synthesis of vancomycin model diaryl ether possessing a chlorine atom
H Konishi, T Okuno, S Nishiyama, S Yamamura, K Koyasu, Y Terada
Tetrahedron letters 37 (48), 8791-8794, 1996
391996
A high-affinity monoclonal antibody against the FLAG tag useful for G-protein-coupled receptor study
F Sasaki, T Okuno, K Saeki, L Min, N Onohara, H Kato, T Shimizu, ...
Analytical biochemistry 425 (2), 157-165, 2012
372012
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