MitoFates: improved prediction of mitochondrial targeting sequences and their cleavage sites*[S] Y Fukasawa, J Tsuji, SC Fu, K Tomii, P Horton, K Imai Molecular & Cellular Proteomics 14 (4), 1113-1126, 2015 | 554 | 2015 |
BI-3406, a potent and selective SOS1–KRAS interaction inhibitor, is effective in KRAS-driven cancers through combined MEK inhibition MH Hofmann, M Gmachl, J Ramharter, F Savarese, D Gerlach, ... Cancer Discovery 11 (1), 142-157, 2021 | 333 | 2021 |
LocNES: a computational tool for locating classical NESs in CRM1 cargo proteins D Xu, K Marquis, J Pei, SC Fu, T Cağatay, NV Grishin, YM Chook Bioinformatics 31 (9), 1357-1365, 2015 | 155 | 2015 |
ValidNESs: a database of validated leucine-rich nuclear export signals SC Fu, HC Huang, P Horton, HF Juan Nucleic acids research 41 (D1), D338-D343, 2013 | 100 | 2013 |
Nuclear export receptor CRM1 recognizes diverse conformations in nuclear export signals HYJ Fung, SC Fu, YM Chook elife 6, e23961, 2017 | 92 | 2017 |
Structural determinants of nuclear export signal orientation in binding to exportin CRM1 HYJ Fung, SC Fu, CA Brautigam, YM Chook elife 4, e10034, 2015 | 92 | 2015 |
Prediction of leucine-rich nuclear export signal containing proteins with NESsential SC Fu, K Imai, P Horton Nucleic acids research 39 (16), e111-e111, 2011 | 80 | 2011 |
Efficacy, safety, and biomarker analysis of combined PD-L1 (atezolizumab) and VEGF (bevacizumab) blockade in advanced malignant peritoneal mesothelioma K Raghav, S Liu, MJ Overman, AF Willett, M Knafl, SC Fu, A Malpica, ... Cancer discovery 11 (11), 2738-2747, 2021 | 59 | 2021 |
Correlation of CRM1-NES affinity with nuclear export activity SC Fu, HYJ Fung, T Cağatay, J Baumhardt, YM Chook Molecular biology of the cell 29 (17), 2037-2044, 2018 | 49 | 2018 |
BI-3406 and BI 1701963: Potent and selective SOS1:: KRAS inhibitors induce regressions in combination with MEK inhibitors or irinotecan D Gerlach, M Gmachl, J Ramharter, J Teh, SC Fu, F Trapani, D Kessler, ... Cancer research 80 (16_Supplement), 1091-1091, 2020 | 37 | 2020 |
Assessment of clinical response following atezolizumab and bevacizumab treatment in patients with neuroendocrine tumors: a nonrandomized clinical trial DM Halperin, S Liu, A Dasari, D Fogelman, P Bhosale, A Mahvash, ... JAMA oncology 8 (6), 904-909, 2022 | 23 | 2022 |
ScreenCap3: Improving prediction of caspase‐3 cleavage sites using experimentally verified noncleavage sites SC Fu, K Imai, T Sawasaki, K Tomii Proteomics 14 (17-18), 2042-2046, 2014 | 13 | 2014 |
Abstract PL06-01: Discovery of BI-3406: A potent and selective SOS1:: KRAS inhibitor opens a new approach for treating KRAS-driven tumors MH Hofmann, M Gmachl, J Ramharter, F Savarese, D Gerlach, ... Molecular Cancer Therapeutics 18 (12_Supplement), PL06-01-PL06-01, 2019 | 10 | 2019 |
Efficacy, safety, and biomarker analysis of combined PD-L1 (atezolizumab) and VEGF (bevacizumab) blockade in advanced malignant peritoneal mesothelioma. Cancer Discov.(2021) 11 … K Raghav, S Liu, MJ Overman, AF Willett, M Knafl, SC Fu, A Malpica, ... DOI: https://doi. org/10.1158/2159-8290. CD-21-0331, 2738-2747, 0 | 9 | |
BI-3406, a Potent and Selective SOS1-KRAS Interaction Inhibitor, Is Effective in KRAS-Driven Cancers through Combined MEK Inhibition. Cancer Discov 11, 142–157, doi: 10.1158 … MH Hofmann, M Gmachl, J Ramharter, F Savarese, D Gerlach, ... CD-20-0142, 2021 | 7 | 2021 |
Comprehensive genomic profiling of malignant peritoneal mesothelioma (MPeM) reveals key genomic alterations (GAs) distinct from malignant pleural mesothelioma (MPM). LO Chapman, MJ Overman, A Willett, M Knafl, SC Fu, A Malpica, C Scally, ... Journal of Clinical Oncology 39 (15_suppl), 8557-8557, 2021 | | 2021 |
Mitochondrial protein cleavage site predictor Y Fukasawa, R Wan, SC Fu, J Tsuji, N Sakiyama, K Imai, P Horton 2010 IEEE International Conference on Bioinformatics and Biomedicine …, 2010 | | 2010 |
Genome informatics: advances in theory and practice S Fu, P Horton Genome Medicine 2, 1-2, 2010 | | 2010 |
2P-241 Sequence Analysis of Nuclear Export Signals (Bioinformatics: Functional genomics, The 47th Annual Meeting of the Biophysical Society of Japan) SC Fu, P Horton Seibutsu Butsuri 49 (supplement), S144-S145, 2009 | | 2009 |
2P-241 核外移行シグナルの配列解析 (生命情報科学-機能ゲノミクス, 第 47 回日本生物物理学会年会) F Szu-Chin, H Paul 生物物理 49 (supplement), S144-S145, 2009 | | 2009 |