IACS-010759, a potent inhibitor of glycolysis-deficient hypoxic tumor cells, inhibits mitochondrial respiratory complex I through a unique mechanism A Tsuji, T Akao, T Masuya, M Murai, H Miyoshi Journal of Biological Chemistry 295 (21), 7481-7491, 2020 | 53 | 2020 |
Site-specific chemical labeling of mitochondrial respiratory complex I through ligand-directed tosylate chemistry T Masuya, M Murai, K Ifuku, H Morisaka, H Miyoshi Biochemistry 53 (14), 2307-2317, 2014 | 35 | 2014 |
Pinpoint chemical modification of Asp160 in the 49 kDa subunit of bovine mitochondrial complex I via a combination of ligand-directed tosyl chemistry and click chemistry T Masuya, M Murai, H Morisaka, H Miyoshi Biochemistry 53 (49), 7816-7823, 2014 | 27 | 2014 |
Oversized ubiquinones as molecular probes for structural dynamics of the ubiquinone reaction site in mitochondrial respiratory complex I S Uno, T Masuya, K Shinzawa-Itoh, J Lasham, O Haapanen, T Shiba, ... Journal of Biological Chemistry 295 (8), 2449-2463, 2020 | 23 | 2020 |
Comprehensive understanding of multiple actions of anticancer drug tamoxifen in isolated mitochondria Y Unten, M Murai, T Koshitaka, K Kitao, O Shirai, T Masuya, H Miyoshi Biochimica et Biophysica Acta (BBA)-Bioenergetics 1863 (2), 148520, 2022 | 13 | 2022 |
Genomic mushroom hunting decrypts coprinoferrin, a siderophore secondary metabolite vital to fungal cell development Y Tsunematsu, J Takanishi, S Asai, T Masuya, T Nakazawa, K Watanabe Organic letters 21 (18), 7582-7586, 2019 | 13 | 2019 |
Inhibitors of a Na+-pumping NADH-ubiquinone oxidoreductase play multiple roles to block enzyme function T Masuya, Y Sano, H Tanaka, NL Butler, T Ito, T Tosaki, JE Morgan, ... Journal of Biological Chemistry 295 (36), 12739-12754, 2020 | 11 | 2020 |
Biosynthesis of lagopodins in mushroom involves a complex network of oxidation reactions T Masuya, Y Tsunematsu, Y Hirayama, M Sato, H Noguchi, T Nakazawa, ... Organic & Biomolecular Chemistry 17 (2), 234-239, 2019 | 11 | 2019 |
Pinpoint chemical modification of the quinone-access channel of mitochondrial complex I via a two-step conjugation reaction T Masuya, M Murai, T Ito, S Aburaya, W Aoki, H Miyoshi Biochemistry 56 (32), 4279-4287, 2017 | 11 | 2017 |
Cryo-EM structures of Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae J Kishikawa, M Ishikawa, T Masuya, M Murai, Y Kitazumi, NL Butler, ... Nature Communications 13 (1), 4082, 2022 | 10 | 2022 |
Pinpoint dual chemical cross-linking explores the structural dynamics of the ubiquinone reaction site in mitochondrial complex I T Masuya, S Uno, M Murai, H Miyoshi Biochemistry 60 (10), 813-824, 2021 | 8 | 2021 |
Specific methylation of Asp160 (49 kDa subunit) located inside the quinone binding cavity of bovine mitochondrial complex I M Murai, H Inaoka, T Masuya, S Aburaya, W Aoki, H Miyoshi Biochemistry 55 (23), 3189-3197, 2016 | 7 | 2016 |
Diverse reaction behaviors of artificial ubiquinones in mitochondrial respiratory complex I S Uno, T Masuya, O Zdorevskyi, R Ikunishi, K Shinzawa-Itoh, J Lasham, ... Journal of Biological Chemistry 298 (7), 2022 | 6 | 2022 |
Uncovering hidden sesquiterpene biosynthetic pathway through expression boost area-mediated productivity enhancement in basidiomycete S Asai, Y Tsunematsu, T Masuya, J Otaka, H Osada, K Watanabe The Journal of Antibiotics 73 (10), 721-728, 2020 | 6 | 2020 |
Characterization of the reaction of decoupling ubiquinone with bovine mitochondrial respiratory complex I T Masuya, K Okuda, M Murai, H Miyoshi Bioscience, Biotechnology, and Biochemistry 80 (8), 1464-1469, 2016 | 6 | 2016 |
Natural tetramic acids elicit multiple inhibitory actions against mitochondrial machineries presiding over oxidative phosphorylation Y Unten, M Murai, K Sakai, Y Asami, T Yamamoto, T Masuya, H Miyoshi Bioscience, Biotechnology, and Biochemistry 85 (12), 2368-2377, 2021 | 4 | 2021 |
Specific chemical modification explores dynamic structure of the NqrB subunit in Na+-pumping NADH-ubiquinone oxidoreductase from Vibrio cholerae M Ishikawa, T Masuya, H Tanaka, W Aoki, N Hantman, NL Butler, M Murai, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1862 (8), 148432, 2021 | 4 | 2021 |
Oxidative Modification Enzymes in Polyketide Biosynthetic Pathways Y Tsunematsu, Y Hirayama, T Masuya, K Watanabe Elsevier, 2020 | 3 | 2020 |
Respiratory complex I in mitochondrial membrane catalyzes oversized ubiquinones R Ikunishi, R Otani, T Masuya, K Shinzawa-Itoh, T Shiba, M Murai, ... Journal of Biological Chemistry 299 (8), 2023 | 2 | 2023 |
Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I) A Tsuji, T Masuya, N Arichi, S Inuki, M Murai, H Miyoshi, H Ohno ACS Medicinal Chemistry Letters 14 (2), 211-216, 2023 | 1 | 2023 |