Glucosylation of Rho proteins by Clostridium difficile toxin B I Just, J Selzer, M Wilm, C Eichel-Streiber, M Mann, K Aktories Nature 375 (6531), 500-503, 1995 | 1284 | 1995 |
Microinjection of recombinant p21rho induces rapid changes in cell morphology. HF Paterson, AJ Self, MD Garrett, I Just, K Aktories, A Hall The Journal of cell biology 111 (3), 1001-1007, 1990 | 920 | 1990 |
Allgemeine und spezielle Pharmakologie und Toxikologie: Begründet von W. Forth, D. Henschler, W. Rummel K Aktories, U Förstermann, FB Hofmann, K Starke Elsevier Health Sciences, 2017 | 878* | 2017 |
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton. S Valitutti, M Dessing, K Aktories, H Gallati, A Lanzavecchia The Journal of experimental medicine 181 (2), 577-584, 1995 | 664 | 1995 |
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1 G Schmidt, P Sehr, M Wilm, J Selzer, M Mann, K Aktories Nature 387 (6634), 725-729, 1997 | 648 | 1997 |
Botulinum C2 toxin ADP-ribosylates actin K Aktories, M Bärmann, I Ohishi, S Tsuyama, KH Jakobs, E Habermann Nature 322 (6077), 390-392, 1986 | 631 | 1986 |
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis S Srinivasan, F Wang, S Glavas, A Ott, F Hofmann, K Aktories, D Kalman, ... The Journal of cell biology 160 (3), 375-385, 2003 | 614 | 2003 |
The Enterotoxin from Clostridium difficile (ToxA) Monoglucosylates the Rho Proteins∗ I Just, M Wilm, J Selzer, G Rex, C von Eichel-Streiber, M Mann, K Aktories Journal of Biological Chemistry 270 (23), 13932-13936, 1995 | 593 | 1995 |
Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance DN Gerding, S Johnson, M Rupnik, K Aktories Gut microbes 5 (1), 15-27, 2014 | 564 | 2014 |
Binary Bacterial Toxins: Biochemistry, Biology, and Applications of Common Clostridium and Bacillus Proteins H Barth, K Aktories, MR Popoff, BG Stiles Microbiology and Molecular Biology Reviews 68 (3), 373-402, 2004 | 563 | 2004 |
Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase S Wahl, H Barth, T Ciossek, K Aktories, BK Mueller The Journal of cell biology 149 (2), 263-270, 2000 | 538 | 2000 |
Clostridium difficile Toxin CDT Induces Formation of Microtubule-Based Protrusions and Increases Adherence of Bacteria C Schwan, B Stecher, T Tzivelekidis, M van Ham, M Rohde, WD Hardt, ... PLoS pathogens 5 (10), e1000626, 2009 | 455 | 2009 |
GAP activity of the Yersinia YopE cytotoxin specifically targets the Rho pathway: a mechanism for disruption of actin microfilament structure U Von Pawel‐Rammingen, MV Telepnev, G Schmidt, K Aktories, ... Molecular microbiology 36 (3), 737-748, 2000 | 436 | 2000 |
Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O I Walev, SC Bhakdi, F Hofmann, N Djonder, A Valeva, K Aktories, ... Proceedings of the National Academy of Sciences 98 (6), 3185-3190, 2001 | 414 | 2001 |
The N-terminal domain of Pseudomonas aeruginosaexoenzyme S is a GTPase-activating protein for Rho GTPases UM Goehring, G Schmidt, KJ Pederson, K Aktories, JT Barbieri Journal of Biological Chemistry 274 (51), 36369-36372, 1999 | 401 | 1999 |
Structure and mode of action of clostridial glucosylating toxins: the ABCD model T Jank, K Aktories Trends in microbiology 16 (5), 222-229, 2008 | 367 | 2008 |
Bacterial cytotoxins: targeting eukaryotic switches K Aktories, JT Barbieri Nature Reviews Microbiology 3 (5), 397-410, 2005 | 351 | 2005 |
Bacterial protein toxins that modify host regulatory GTPases K Aktories Nature Reviews Microbiology 9 (7), 487-498, 2011 | 350 | 2011 |
The rho gene product expressed in E. coli is a substrate of botulinum ADP-ribosyltransferase C3 K Aktories, U Braun, S Rösener, I Just, A Hall Biochemical and biophysical research communications 158 (1), 209-213, 1989 | 332 | 1989 |
Clostridium difficile Toxin Biology K Aktories, C Schwan, T Jank Annual review of microbiology 71 (1), 281-307, 2017 | 324 | 2017 |