Transplantation of genetically corrected human iPSC-derived progenitors in mice with limb-girdle muscular dystrophy FS Tedesco, MFM Gerli, L Perani, S Benedetti, F Ungaro, M Cassano, ... Science translational medicine 4 (140), 140ra89-140ra89, 2012 | 320 | 2012 |
Complete genetic correction of ips cells from Duchenne muscular dystrophy Y Kazuki, M Hiratsuka, M Takiguchi, M Osaki, N Kajitani, H Hoshiya, ... Molecular Therapy 18 (2), 386-393, 2010 | 303 | 2010 |
Stem cell–mediated transfer of a human artificial chromosome ameliorates muscular dystrophy FS Tedesco, H Hoshiya, G D’Antona, MFM Gerli, G Messina, S Antonini, ... Science translational medicine 3 (96), 96ra78-96ra78, 2011 | 183 | 2011 |
Frequent loss of imprinting of IGF2 and MEST in lung adenocarcinoma M Kohda, H Hoshiya, M Katoh, I Tanaka, R Masuda, T Takemura, ... Molecular Carcinogenesis: Published in cooperation with the University of …, 2001 | 132 | 2001 |
Refined human artificial chromosome vectors for gene therapy and animal transgenesis Y Kazuki, H Hoshiya, M Takiguchi, S Abe, Y Iida, M Osaki, M Katoh, ... Gene therapy 18 (4), 384-393, 2011 | 124 | 2011 |
A highly stable and nonintegrated human artificial chromosome (HAC) containing the 2.4 Mb entire human dystrophin gene H Hoshiya, Y Kazuki, S Abe, M Takiguchi, N Kajitani, Y Watanabe, ... Molecular Therapy 17 (2), 309-317, 2009 | 123 | 2009 |
A new imprinted cluster on the human chromosome 7q21-q31, identified by human-mouse monochromosomal hybrids C Okita, M Meguro, H Hoshiya, M Haruta, Y Sakamoto, M Oshimura Genomics 81 (6), 556-559, 2003 | 92 | 2003 |
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans Y Kazuki, K Kobayashi, S Aueviriyavit, T Oshima, Y Kuroiwa, Y Tsukazaki, ... Human molecular genetics 22 (3), 578-592, 2013 | 79 | 2013 |
Repair or replace? Exploiting novel gene and cell therapy strategies for muscular dystrophies S Benedetti, H Hoshiya, FS Tedesco The FEBS journal 280 (17), 4263-4280, 2013 | 76 | 2013 |
Human artificial chromosome with a conditional centromere for gene delivery and gene expression Y Iida, JH Kim, Y Kazuki, H Hoshiya, M Takiguchi, M Hayashi, I Erliandri, ... DNA research 17 (5), 293-301, 2010 | 71 | 2010 |
A Novel Human Artificial Chromosome Vector Provides Effective Cell Lineage–Specific Transgene Expression in Human Mesenchymal Stem Cells X Ren, M Katoh, H Hoshiya, A Kurimasa, T Inoue, F Ayabe, K Shibata, ... Stem Cells 23 (10), 1608-1616, 2005 | 60 | 2005 |
Predominant maternal expression of the mouse Atp10c in hippocampus and olfactory bulb A Kashiwagi, M Meguro, H Hoshiya, M Haruta, F Ishino, T Shibahara, ... Journal of human genetics 48 (4), 194-198, 2003 | 54 | 2003 |
Correction of a genetic defect in multipotent germline stem cells using a human artificial chromosome Y Kazuki, H Hoshiya, Y Kai, S Abe, M Takiguchi, M Osaki, S Kawazoe, ... Gene therapy 15 (8), 617-624, 2008 | 44 | 2008 |
Calcr, a brain-specific imprinted mouse calcitonin receptor gene in the imprinted cluster of the proximal region of chromosome 6 H Hoshiya, M Meguro, A Kashiwagi, C Okita, M Oshimura Journal of human genetics 48 (4), 208-211, 2003 | 40 | 2003 |
Reversible immortalisation enables genetic correction of human muscle progenitors and engineering of next‐generation human artificial chromosomes for Duchenne muscular dystrophy S Benedetti, N Uno, H Hoshiya, M Ragazzi, G Ferrari, Y Kazuki, LA Moyle, ... EMBO molecular medicine 10 (2), 254-275, 2018 | 36 | 2018 |
Mesoangioblasts at 20: from the embryonic aorta to the patient bed G Cossu, R Tonlorenzi, S Brunelli, M Sampaolesi, G Messina, E Azzoni, ... Frontiers in Genetics 13, 1056114, 2023 | 3 | 2023 |
Humanized CYP3A mice:(1) Construction of humanized MODEL mice CONTAINING the CYP3A cluster for drug screening Y Kazuki, S Abe, M Takiguchi, H Hoshiya, N Kajitani, T Yoshino, ... DRUG METABOLISM REVIEWS 42, 74-74, 2010 | 2 | 2010 |
Narrowed abrogation of the Angelman syndrome critical interval on human chromosome 15 does not interfere with epigenotype maintenance in somatic cells M Haruta, M Meguro, Y Sakamoto, H Hoshiya, A Kashiwagi, Y Kaneko, ... Journal of human genetics 50 (3), 124-132, 2005 | 2 | 2005 |
Combining iPS cell-derived myogenic progenitors and human artificial chromosomes for genomic-integration-free, systemically deliverable cell and gene therapy of Duchenne … G Ferrari, LM Moyle, H Hoshiya, M Ragazzi, SM Maffioletti, T Casteels, ... HUMAN GENE THERAPY 29 (12), A62-A62, 2018 | | 2018 |
Next-Generation Human Artificial Chromosomes for Autologous Cell Therapy of Duchenne Muscular Dystrophy S Benedetti, N Uno, H Hoshiya, M Ragazzi, G Ferrari, Y Kazuki, LA Moyle, ... MOLECULAR THERAPY 26 (5), 395-396, 2018 | | 2018 |