Masahito Ikawa

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Masaru OkabeProfessor Emeritus, Osaka UniversityVerified email at biken.osaka-u.ac.jp
Yoshitaka FujiharaDirector, Department of Advanced Medical Technologies, NCVCVerified email at ncvc.go.jp
Haruhiko MiyataResearch Institute for Microbial Diseases, Osaka UniversityVerified email at biken.osaka-u.ac.jp
Ayako Isotani大阪大学Verified email at biken.osaka-u.ac.jp
Martin MatzukDirector, Center for Drug Discovery, and Chair and Professor, Department of Pathology & ImmunologyVerified email at bcm.edu
Yuhkoh SatouhInstitute for Molecular and Cellular Regulation, Gunma UniversityVerified email at gunma-u.ac.jp
Naokazu InoueFukushima Medical UniversityVerified email at fmu.ac.jp
Seiya OuraUT Southwestern medical centerVerified email at UTSouthwestern.edu
Tomoko NakanishiCenter for Biomedical Research Resources, Juntendo UniversityVerified email at juntendo.ac.jp
Keisuke SHIMADAResearch Institute for Microbial Diseases, Osaka UniversityVerified email at biken.osaka-u.ac.jp
Yonggang LuAssociate Professor, WPI-PRIMe, Osaka UniversityVerified email at osaka-u.ac.jp
Inder VermaSalk InstituteVerified email at salk.edu
Toru NAKANOVerified email at patho.med.osaka-u.ac.jp
Daiji KiyozumiResearch Institute of Environmental Medicine, Nagoya UniversityVerified email at riem.nagoya-u.ac.jp
Kazuo YamagataKindai UniversityVerified email at waka.kindai.ac.jp
masanaga mutouUniversity of Kansas Medical CenterVerified email at kumc.edu
Vinay TergaonkarimcbVerified email at imcb.a-star.edu.sg
Ferheen AbbasiUC Davis School of MedicineVerified email at ucdavis.edu
Robert John AitkenPro Vice Chancellor Faculty of Health and Medicine and Laureate Professor of Biological SciencesVerified email at newcastle.edu.au
Shin KobayashiNational Institute of Advanced Industrial Science and Technology (AIST)Verified email at aist.go.jp

Masahito Ikawa

Professor, Research Institute for Microbial Diseases, Osaka University

Verified email at biken.osaka-u.ac.jp - Homepage

Fertilization Spermatogenesis Reproductive biology Biotechnology Genome engineering


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Green mice'as a source of ubiquitous green cells M Okabe, M Ikawa, K Kominami, T Nakanishi, Y Nishimune FEBS letters 407 (3), 313-319, 1997	2981	1997
DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes S Kuramochi-Miyagawa, T Watanabe, K Gotoh, Y Totoki, A Toyoda, ... Genes & development 22 (7), 908-917, 2008	1044	2008
Engineered CRISPR-Cas9 nuclease with expanded targeting space H Nishimasu, X Shi, S Ishiguro, L Gao, S Hirano, S Okazaki, T Noda, ... Science 361 (6408), 1259-1262, 2018	981	2018
The immunoglobulin superfamily protein Izumo is required for sperm to fuse with eggs N Inoue, M Ikawa, A Isotani, M Okabe Nature 434 (7030), 234-238, 2005	961	2005
Mili, a mammalian member of piwi family gene, is essential for spermatogenesis S Kuramochi-Miyagawa, T Kimura, TW Ijiri, T Isobe, N Asada, Y Fujita, ... Development 131 (4), 839-849, 2004	887	2004
A general method for gene knockdown in mice by using lentiviral vectors expressing small interfering RNA G Tiscornia, O Singer, M Ikawa, IM Verma Proceedings of the National Academy of Sciences 100 (4), 1844-1848, 2003	781	2003
Transgenesis by lentiviral vectors: lack of gene silencing in mammalian embryonic stem cells and preimplantation embryos A Pfeifer, M Ikawa, Y Dayn, IM Verma Proceedings of the National Academy of Sciences 99 (4), 2140-2145, 2002	737	2002
Innate versus learned odour processing in the mouse olfactory bulb K Kobayakawa, R Kobayakawa, H Matsumoto, Y Oka, T Imai, M Ikawa, ... Nature 450 (7169), 503-508, 2007	732	2007
PGC7/Stella protects against DNA demethylation in early embryogenesis T Nakamura, Y Arai, H Umehara, M Masuhara, T Kimura, H Taniguchi, ... Nature cell biology 9 (1), 64-71, 2007	666	2007
Generating green fluorescent mice by germline transmission of green fluorescent ES cells AK Hadjantonakis, M Gertsenstein, M Ikawa, M Okabe, A Nagy Mechanisms of development 76 (1), 79-90, 1998	592	1998
Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA D Mashiko, Y Fujihara, Y Satouh, H Miyata, A Isotani, M Ikawa Scientific reports 3 (1), 3355, 2013	461	2013
Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model K Kumasawa, M Ikawa, H Kidoya, H Hasuwa, T Saito-Fujita, Y Morioka, ... Proceedings of the National Academy of Sciences 108 (4), 1451-1455, 2011	420	2011
A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome K Nimura, K Ura, H Shiratori, M Ikawa, M Okabe, RJ Schwartz, Y Kaneda Nature 460 (7252), 287-291, 2009	401	2009
Fertilization: a sperm’s journey to and interaction with the oocyte M Ikawa, N Inoue, AM Benham, M Okabe The Journal of clinical investigation 120 (4), 984-994, 2010	387	2010
Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality Y Hamada, Y Kadokawa, M Okabe, M Ikawa, JR Coleman, Y Tsujimoto Development 126 (15), 3415-3424, 1999	369	1999
Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase) M Matsuki, F Yamashita, A Ishida-Yamamoto, K Yamada, C Kinoshita, ... Proceedings of the National Academy of Sciences 95 (3), 1044-1049, 1998	355	1998
Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation T Murakami, A Saito, S Hino, S Kondo, S Kanemoto, K Chihara, H Sekiya, ... Nature cell biology 11 (10), 1205-1211, 2009	349	2009
The putative chaperone calmegin is required for sperm fertility M Ikawa, I Wada, K Kominami, D Watanabe, K Toshimori, Y Nishimune, ... Nature 387 (6633), 607-611, 1997	331	1997
The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice W Shi, A Kumanogoh, C Watanabe, J Uchida, X Wang, T Yasui, ... Immunity 13 (5), 633-642, 2000	330	2000
Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: adipocyte glycerol permeability as a novel regulator of fat accumulation M Hara-Chikuma, E Sohara, T Rai, M Ikawa, M Okabe, S Sasaki, ... Journal of Biological Chemistry 280 (16), 15493-15496, 2005	327	2005

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