| Novel trimodal MALDI imaging mass spectrometry (IMS3) at 10 μm reveals spatial lipid and peptide correlates implicated in Aβ plaque pathology in Alzheimer’s disease I Kaya, D Brinet, W Michno, M Başkurt, H Zetterberg, K Blenow, ... ACS chemical neuroscience 8 (12), 2778-2790, 2017 | 101 | 2017 |
| Delineating amyloid plaque associated neuronal sphingolipids in transgenic Alzheimer’s disease mice (tgArcSwe) using MALDI imaging mass spectrometry I Kaya, D Brinet, W Michno, S Syvänen, D Sehlin, H Zetterberg, ... ACS chemical neuroscience 8 (2), 347-355, 2017 | 78 | 2017 |
| Histology-compatible MALDI mass spectrometry based imaging of neuronal lipids for subsequent immunofluorescent staining I Kaya, W Michno, D Brinet, Y Iacone, G Zanni, K Blennow, H Zetterberg, ... Analytical chemistry 89 (8), 4685-4694, 2017 | 74 | 2017 |
| Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology W Michno, S Nyström, P Wehrli, T Lashley, G Brinkmalm, L Guerard, ... Journal of Biological Chemistry 294 (17), 6719-6732, 2019 | 65 | 2019 |
| Lithium accumulates in neurogenic brain regions as revealed by high resolution ion imaging G Zanni, W Michno, E Di Martino, A Tjärnlund-Wolf, J Pettersson, ... Scientific reports 7 (1), 40726, 2017 | 50 | 2017 |
| Probing amyloid‐β pathology in transgenic Alzheimer's disease (tgArcSwe) mice using MALDI imaging mass spectrometry L Carlred, W Michno, I Kaya, P Sjövall, S Syvänen, J Hanrieder Journal of neurochemistry 138 (3), 469-478, 2016 | 48 | 2016 |
| Molecular imaging mass spectrometry for probing protein dynamics in neurodegenerative disease pathology W Michno, PM Wehrli, K Blennow, H Zetterberg, J Hanrieder Journal of neurochemistry 151 (4), 488-506, 2019 | 47 | 2019 |
| GM1 locates to mature amyloid structures implicating a prominent role for glycolipid-protein interactions in Alzheimer pathology W Michno, PM Wehrli, H Zetterberg, K Blennow, J Hanrieder Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1867 (5), 458-467, 2019 | 43 | 2019 |
| Multimodal chemical imaging of amyloid plaque polymorphism reveals Aβ aggregation dependent anionic lipid accumulations and metabolism W Michno, I Kaya, S Nyström, L Guerard, KPR Nilsson, ... Analytical chemistry 90 (13), 8130-8138, 2018 | 43 | 2018 |
| Aggregated Aβ1-42 is selectively toxic for neurons, whereas glial cells produce mature fibrils with low toxicity in Drosophila M Jonson, S Nyström, A Sandberg, M Carlback, W Michno, J Hanrieder, ... Cell chemical biology 25 (5), 595-610. e5, 2018 | 34 | 2018 |
| Following spatial Aβ aggregation dynamics in evolving Alzheimer’s disease pathology by imaging stable isotope labeling kinetics W Michno, KM Stringer, T Enzlein, MK Passarelli, S Escrig, K Vitanova, ... Science Advances 7 (25), eabg4855, 2021 | 27 | 2021 |
| The Uppsala APP deletion causes early onset autosomal dominant Alzheimer’s disease by altering APP processing and increasing amyloid β fibril formation M Pagnon de la Vega, V Giedraitis, W Michno, L Kilander, G Güner, ... Science translational medicine 13 (606), eabc6184, 2021 | 25 | 2021 |
| Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging W Michno, PM Wehrli, S Koutarapu, C Marsching, K Minta, J Ge, ... Journal of Neurochemistry 160 (4), 482-498, 2022 | 22 | 2022 |
| Computational analysis of Alzheimer amyloid plaque composition in 2D-and elastically reconstructed 3D-MALDI MS images T Enzlein, J Cordes, B Munteanu, W Michno, L Serneels, B De Strooper, ... Analytical chemistry 92 (21), 14484-14493, 2020 | 20 | 2020 |
| Chemical imaging of evolving amyloid plaque pathology and associated Aβ peptide aggregation in a transgenic mouse model of Alzheimer’s disease W Michno, P Wehrli, SR Meier, D Sehlin, S Syvänen, H Zetterberg, ... Journal of Neurochemistry 152 (5), 602-616, 2020 | 20 | 2020 |
| MALDI imaging delineates hippocampal glycosphingolipid changes associated with neurotoxin induced proteopathy following neonatal BMAA exposure O Karlsson, W Michno, Y Ransome, J Hanrieder Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1865 (7), 740-746, 2017 | 17 | 2017 |
| Chemometric Strategies for Sensitive Annotation and Validation of Anatomical Regions of Interest in Complex Imaging Mass Spectrometry Data PM Wehrli, W Michno, K Blennow, H Zetterberg, J Hanrieder Journal of The American Society for Mass Spectrometry 30 (11), 2278-2288, 2019 | 14 | 2019 |
| Refining the amyloid β peptide and oligomer fingerprint ambiguities in Alzheimer’s disease: Mass spectrometric molecular characterization in brain, cerebrospinal fluid, blood … W Michno, K Blennow, H Zetterberg, G Brinkmalm Journal of Neurochemistry 159 (2), 234-257, 2021 | 12 | 2021 |
| Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells J Hsu, N Fatuzzo, N Weng, W Michno, W Dong, M Kienle, Y Dai, A Pasca, ... Journal of Biological Chemistry 299 (2), 2023 | 9 | 2023 |
| Herpes simplex virus 1 and 2 infections during differentiation of human cortical neurons P Bergström, E Trybala, CE Eriksson, M Johansson, TM Satir, S Widéhn, ... Viruses 13 (10), 2072, 2021 | 8 | 2021 |
