Hirotaka Nagai
Hirotaka Nagai
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Diameter and rigidity of multiwalled carbon nanotubes are critical factors in mesothelial injury and carcinogenesis
H Nagai, Y Okazaki, SH Chew, N Misawa, Y Yamashita, S Akatsuka, ...
Proceedings of the national academy of sciences 108 (49), E1330-E1338, 2011
Biopersistent fiber-induced inflammation and carcinogenesis: lessons learned from asbestos toward safety of fibrous nanomaterials
H Nagai, S Toyokuni
Archives of Biochemistry and Biophysics 502 (1), 1-7, 2010
Iron overload signature in chrysotile‐induced malignant mesothelioma
L Jiang, S Akatsuka, H Nagai, SH Chew, H Ohara, Y Okazaki, ...
The Journal of pathology 228 (3), 366-377, 2012
Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer
S Akatsuka, Y Yamashita, H Ohara, YT Liu, M Izumiya, K Abe, M Ochiai, ...
Public Library of Science 7 (8), e43403, 2012
Regulation of cortical activity and arousal by the matrix cells of the ventromedial thalamic nucleus
S Honjoh, S Sasai, SS Schiereck, H Nagai, G Tononi, C Cirelli
Nature Communications 9 (1), 2100, 2018
Differences and similarities between carbon nanotubes and asbestos fibers during mesothelial carcinogenesis: shedding light on fiber entry mechanism
H Nagai, S Toyokuni
Cancer science 103 (8), 1378-1390, 2012
Asbestos surface provides a niche for oxidative modification
H Nagai, T Ishihara, WH Lee, H Ohara, Y Okazaki, K Okawa, S Toyokuni
Cancer science 102 (12), 2118-2125, 2011
Characteristics and modifying factors of asbestos‐induced oxidative DNA damage
L Jiang, H Nagai, H Ohara, S Hara, M Tachibana, S Hirano, Y Shinohara, ...
Cancer science 99 (11), 2142-2151, 2008
Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma
Q Hu, S Akatsuka, Y Yamashita, H Ohara, H Nagai, Y Okazaki, ...
Laboratory investigation 90 (3), 360-373, 2010
Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats
H Nagai, Y Okazaki, SH Chew, N Misawa, Y Miyata, H Shinohara, ...
Pathology international 63 (9), 457-462, 2013
Social defeat stress-specific increase in c-Fos expression in the extended amygdala in mice: Involvement of dopamine D1 receptor in the medial prefrontal cortex
C Numa, H Nagai, M Taniguchi, M Nagai, R Shinohara, T Furuyashiki
Scientific reports 9 (1), 16670, 2019
Deferasirox induces mesenchymal–Epithelial transition in crocidolite-induced mesothelial carcinogenesis in rats
H Nagai, Y Okazaki, SH Chew, N Misawa, H Yasui, S Toyokuni
Cancer Prevention Research 6 (11), 1222-1230, 2013
Sleep consolidates motor learning of complex movement sequences in mice
H Nagai, L de Vivo, M Bellesi, MF Ghilardi, G Tononi, C Cirelli
Sleep 40 (2), zsw059, 2017
Single-shot 10K proteome approach: over 10,000 protein identifications by data-independent acquisition-based single-shot proteomics with ion mobility spectrometry
Y Kawashima, H Nagai, R Konno, M Ishikawa, D Nakajima, H Sato, ...
Journal of proteome research 21 (6), 1418-1427, 2022
Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells
S Funahashi, Y Okazaki, D Ito, A Asakawa, H Nagai, M Tajima, ...
Journal of Clinical Biochemistry and Nutrition 56 (2), 111-117, 2015
Connective tissue growth factor and β‐catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma
L Jiang, Y Yamashita, SH Chew, S Akatsuka, S Ukai, S Wang, H Nagai, ...
The Journal of Pathology 233 (4), 402-414, 2014
Evidence for sleep-dependent synaptic renormalization in mouse pups
L de Vivo, H Nagai, N De Wispelaere, GM Spano, W Marshall, M Bellesi, ...
Sleep 42 (11), zsz184, 2019
Metamorphosis of mesothelial cells with active horizontal motility in tissue culture
H Nagai, SH Chew, Y Okazaki, S Funahashi, T Namba, T Kato, ...
Scientific Reports 3 (1), 1144, 2013
Repeated social defeat stress impairs attentional set shifting irrespective of social avoidance and increases female preference associated with heightened anxiety
S Higashida, H Nagai, K Nakayama, R Shinohara, M Taniguchi, M Nagai, ...
Scientific reports 8 (1), 10454, 2018
Rat model demonstrates a high risk of tremolite but a low risk of anthophyllite for mesothelial carcinogenesis
D Aierken, Y Okazaki, SH Chew, A Sakai, Y Wang, H Nagai, N Misawa, ...
Nagoya Journal of Medical Science 76 (1-2), 149, 2014
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