DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants J Piñero, À Bravo, N Queralt-Rosinach, A Gutiérrez-Sacristán, J Deu-Pons, ... Nucleic acids research, gkw943, 2016 | 2151 | 2016 |
The DisGeNET knowledge platform for disease genomics: 2019 update J Piñero, JM Ramírez-Anguita, J Saüch-Pitarch, F Ronzano, E Centeno, ... Nucleic acids research 48 (D1), D845-D855, 2020 | 1902 | 2020 |
DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes J Piñero, N Queralt-Rosinach, À Bravo, J Deu-Pons, A Bauer-Mehren, ... Database 2015, 2015 | 1051 | 2015 |
The DisGeNET cytoscape app: Exploring and visualizing disease genomics data J Piñero, J Saüch, F Sanz, LI Furlong Computational and structural biotechnology journal 19, 2960-2967, 2021 | 286 | 2021 |
Extraction of relations between genes and diseases from text and large-scale data analysis: implications for translational research À Bravo, J Piñero, N Queralt-Rosinach, M Rautschka, LI Furlong BMC bioinformatics 16, 1-17, 2015 | 255 | 2015 |
PsyGeNET: a knowledge platform on psychiatric disorders and their genes A Gutiérrez-Sacristán, S Grosdidier, O Valverde, M Torrens, À Bravo, ... Bioinformatics 31 (18), 3075-3077, 2015 | 96 | 2015 |
Network medicine analysis of COPD multimorbidities S Grosdidier, A Ferrer, R Faner, J Piñero, J Roca, B Cosío, A Agustí, ... Respiratory research 15, 1-11, 2014 | 79 | 2014 |
DisGeNET-RDF: harnessing the innovative power of the Semantic Web to explore the genetic basis of diseases N Queralt-Rosinach, J Pinero, À Bravo, F Sanz, LI Furlong Bioinformatics 32 (14), 2236-2238, 2016 | 78 | 2016 |
Capturing variation impact on molecular interactions in the IMEx Consortium mutations data set N Del-Toro, M Duesbury, M Koch, L Perfetto, A Shrivastava, D Ochoa, ... Nature communications 10 (1), 10, 2019 | 58 | 2019 |
Automatic filtering and substantiation of drug safety signals A Bauer-Mehren, EM van Mullingen, P Avillach, MC Carrascosa, ... PLoS computational biology 8 (4), e1002457, 2012 | 49 | 2012 |
In silico models in drug development: where we are J Piñero, LI Furlong, F Sanz Current Opinion in Pharmacology 42, 111-121, 2018 | 47 | 2018 |
Proximal pathway enrichment analysis for targeting comorbid diseases via network endopharmacology J Aguirre-Plans, J Piñero, J Menche, F Sanz, LI Furlong, HHHW Schmidt, ... Pharmaceuticals 11 (3), 61, 2018 | 38 | 2018 |
Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing J Piñero, A Berenstein, A Gonzalez-Perez, A Chernomoretz, LI Furlong Scientific Reports 6 (1), 24570, 2016 | 37 | 2016 |
GUILDify v2. 0: A tool to identify molecular networks underlying human diseases, their comorbidities and their druggable targets J Aguirre-Plans, J Piñero, F Sanz, LI Furlong, N Fernandez-Fuentes, ... Journal of molecular biology 431 (13), 2477-2484, 2019 | 36 | 2019 |
Genetic and functional characterization of disease associations explains comorbidity C Rubio-Perez, E Guney, D Aguilar, J Piñero, J Garcia-Garcia, B Iadarola, ... Scientific Reports 7 (1), 6207, 2017 | 36 | 2017 |
The eTRANSAFE project on translational safety assessment through integrative knowledge management: achievements and perspectives F Pognan, T Steger-Hartmann, C Díaz, N Blomberg, F Bringezu, K Briggs, ... Pharmaceuticals 14 (3), 237, 2021 | 27 | 2021 |
Nerve growth factor and striatal glutathione metabolism in a rat model of Huntington's disease R Cruz-Aguado, LF Turner, CM Díaz, J Piñero Restorative neurology and neuroscience 17 (4), 217-221, 2000 | 26 | 2000 |
Conservation of key members in the course of the evolution of the insulin signaling pathway JP González, OC Farnés, ATR Vasconcelos, AG Pérez Biosystems 95 (1), 7-16, 2009 | 24 | 2009 |
Comorbidity between Alzheimer’s disease and major depression: a behavioural and transcriptomic characterization study in mice A Martín-Sánchez, J Piñero, L Nonell, M Arnal, EM Ribe, ... Alzheimer's Research & Therapy 13, 1-19, 2021 | 21 | 2021 |
A systems approach identifies time-dependent associations of multimorbidities with pancreatic cancer risk P Gomez-Rubio, V Rosato, M Marquez, C Bosetti, E Molina-Montes, ... Annals of oncology 28 (7), 1618-1624, 2017 | 20 | 2017 |