Molecular targeting therapy of cancer: drug resistance, apoptosis and survival signal T Tsuruo, M Naito, A Tomida, N Fujita, T Mashima, H Sakamoto, N Haga Cancer science 94 (1), 15-21, 2003 | 687 | 2003 |
Brain pericytes contribute to the induction and up-regulation of blood–brain barrier functions through transforming growth factor-β production S Dohgu, F Takata, A Yamauchi, S Nakagawa, T Egawa, M Naito, ... Brain research 1038 (2), 208-215, 2005 | 442 | 2005 |
Functional involvement of P-glycoprotein in blood-brain barrier. T Tatsuta, M Naito, T Oh-Hara, I Sugawara, T Tsuruo Journal of Biological Chemistry 267 (28), 20383-20391, 1992 | 442 | 1992 |
Protein knockdown using methyl bestatin− ligand hybrid molecules: design and synthesis of inducers of ubiquitination-mediated degradation of cellular retinoic acid-binding proteins Y Itoh, M Ishikawa, M Naito, Y Hashimoto Journal of the American Chemical Society 132 (16), 5820-5826, 2010 | 391 | 2010 |
Actin cleavage by CPP-32/apopain during the development of apoptosis T Mashima, M Naito, K Noguchi, DK Miller, DW Nicholson, T Tsuruo Oncogene 14 (9), 1007-1012, 1997 | 352 | 1997 |
The 4F2hc/LAT1 complex transports L-DOPA across the blood–brain barrier T Kageyama, M Nakamura, A Matsuo, Y Yamasaki, Y Takakura, ... Brain research 879 (1-2), 115-121, 2000 | 342 | 2000 |
Brain capillary endothelial cells express two forms of erythropoietin receptor mRNA R Yamaji, T Okada, M Moriya, M Naito, T Tsuruo, K Miyatake, Y Nakano European Journal of Biochemistry 239 (2), 494-500, 1996 | 336 | 1996 |
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function Y Hao, K Sekine, A Kawabata, H Nakamura, T Ishioka, H Ohata, ... Nature cell biology 6 (9), 849-860, 2004 | 318 | 2004 |
A human IAP-family gene, apollon, expressed in human brain cancer cells Z Chen, M Naito, S Hori, T Mashima, T Yamori, T Tsuruo Biochemical and biophysical research communications 264 (3), 847-854, 1999 | 315 | 1999 |
Identification of actin as a substrate of ICE and an ICE-like protease and involvement of an ICE-like protease but not ICE in VP-16-induced U937 apoptosis T Mashima, M Naito, N Fujita, K Noguchi, T Tsuruo Biochemical and biophysical research communications 217 (3), 1185-1192, 1995 | 283 | 1995 |
Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis T Mashima, M Naito, T Tsuruo Oncogene 18 (15), 2423-2430, 1999 | 257 | 1999 |
In vivo knockdown of pathogenic proteins via specific and nongenetic inhibitor of apoptosis protein (IAP)-dependent protein erasers (SNIPERs) N Ohoka, K Okuhira, M Ito, K Nagai, N Shibata, T Hattori, O Ujikawa, ... Journal of Biological Chemistry 292 (11), 4556-4570, 2017 | 247 | 2017 |
Apoxin I, a novel apoptosis-inducing factor with L-amino acid oxidase activity purified from Western diamondback rattlesnake venom S Torii, M Naito, T Tsuruo Journal of Biological Chemistry 272 (14), 9539-9542, 1997 | 244 | 1997 |
ASK1 mediates apoptotic cell death induced by genotoxic stress Z Chen, H Seimiya, M Naito, T Mashima, A Kizaki, S Dan, M Imaizumi, ... Oncogene 18 (1), 173-180, 1999 | 223 | 1999 |
Effect of bioflavonoids on vincristine transport across blood–brain barrier Y Mitsunaga, H Takanaga, H Matsuo, M Naito, T Tsuruo, H Ohtani, ... European journal of pharmacology 395 (3), 193-201, 2000 | 199 | 2000 |
Aspartate-based inhibitor of interleukin-1β-converting enzyme prevents antitumor agent-induced apoptosis in human myeloid leukemia U937 cells T Mashima, M Naito, S Kataoka, H Kawai, T Tsuruo Biochemical and biophysical research communications 209 (3), 907-915, 1995 | 196 | 1995 |
ATP/Mg2+-dependent binding of vincristine to the plasma membrane of multidrug-resistant K562 cells. M Naito, H Hamada, T Tsuruo Journal of Biological Chemistry 263 (24), 11887-11891, 1988 | 192 | 1988 |
Glyoxalase I is involved in resistance of human leukemia cells to antitumor agent-induced apoptosis H Sakamoto, T Mashima, A Kizaki, S Dan, Y Hashimoto, M Naito, ... Blood, The Journal of the American Society of Hematology 95 (10), 3214-3218, 2000 | 191 | 2000 |
Tumor necrosis factor-α mediates the blood–brain barrier dysfunction induced by activated microglia in mouse brain microvascular endothelial cells T Nishioku, J Matsumoto, S Dohgu, N Sumi, K Miyao, F Takata, H Shuto, ... Journal of pharmacological sciences 112 (2), 251-254, 2010 | 182 | 2010 |
Small molecules destabilize cIAP1 by activating auto-ubiquitylation K Sekine, K Takubo, R Kikuchi, M Nishimoto, M Kitagawa, F Abe, ... Journal of Biological Chemistry 283 (14), 8961-8968, 2008 | 179 | 2008 |