Analysis of 13 cell types reveals evidence for the expression of numerous novel primate-and tissue-specific microRNAs E Londin, P Loher, AG Telonis, K Quann, P Clark, Y Jing, E Hatzimichael, ... Proceedings of the National Academy of Sciences 112 (10), E1106-E1115, 2015 | 516 | 2015 |
The GPI-linked protein LY6A drives AAV-PHP. B transport across the blood-brain barrier J Hordeaux, Y Yuan, PM Clark, Q Wang, RA Martino, JJ Sims, P Bell, ... Molecular Therapy 27 (5), 912-921, 2019 | 193 | 2019 |
Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol L Wang, J Smith, C Breton, P Clark, J Zhang, L Ying, Y Che, J Lape, P Bell, ... Nature biotechnology 36 (8), 717-725, 2018 | 119 | 2018 |
Effect of decellularization protocol on the mechanical behavior of porcine descending aorta F John C, C Peter M, C Franco M International journal of biomaterials 2010, 2010 | 118* | 2010 |
Argonaute CLIP-Seq reveals miRNA targetome diversity across tissue types PM Clark, P Loher, K Quann, J Brody, ER Londin, I Rigoutsos Scientific reports 4 (1), 5947, 2014 | 105 | 2014 |
N-BLR, a primate-specific non-coding transcript leads to colorectal cancer invasion and migration I Rigoutsos, SK Lee, SY Nam, S Anfossi, B Pasculli, M Pichler, Y Jing, ... Genome biology 18, 1-21, 2017 | 103 | 2017 |
The next generation of target capture technologies-large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity J Dapprich, D Ferriola, K Mackiewicz, PM Clark, E Rappaport, M D’Arcy, ... BMC genomics 17, 1-14, 2016 | 84 | 2016 |
Molecular dynamics simulations of Ago silencing complexes reveal a large repertoire of admissible ‘seed-less’ targets Z Xia, P Clark, T Huynh, P Loher, Y Zhao, HW Chen, I Rigoutsos, R Zhou Scientific reports 2 (1), 569, 2012 | 83 | 2012 |
Bioinformatics analysis reveals transcriptome and microRNA signatures and drug repositioning targets for IBD and other autoimmune diseases PM Clark, N Dawany, W Dampier, SW Byers, RG Pestell, A Tozeren Inflammatory Bowel Diseases, 2012 | 58 | 2012 |
Clinical exome performance for reporting secondary genetic findings JY Park, P Clark, E Londin, M Sponziello, LJ Kricka, P Fortina Clinical chemistry 61 (1), 213-220, 2015 | 51 | 2015 |
Lm-gvp: an extensible sequence and structure informed deep learning framework for protein property prediction Z Wang, SA Combs, R Brand, MR Calvo, P Xu, G Price, N Golovach, ... Scientific reports 12 (1), 6832, 2022 | 49 | 2022 |
ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing C Breton, PM Clark, L Wang, JA Greig, JM Wilson BMC genomics 21, 1-12, 2020 | 40 | 2020 |
An expanded role for HLA genes: HLA-B encodes a microRNA that regulates IgA and other immune response transcripts N Chitnis, PM Clark, M Kamoun, C Stolle, F Brad Johnson, DS Monos Frontiers in immunology 8, 258055, 2017 | 40 | 2017 |
Performance of exome sequencing for pharmacogenomics ER Londin, P Clark, M Sponziello, LJ Kricka, P Fortina, JY Park Personalized medicine 12 (2), 109-115, 2015 | 30 | 2015 |
Novel and haplotype specific microRNAs encoded by the major histocompatibility complex PM Clark, N Chitnis, M Shieh, M Kamoun, FB Johnson, D Monos Scientific reports 8 (1), 3832, 2018 | 25 | 2018 |
Post-transcriptional Regulation of BRCA2 through Interactions with miR-19a and miR-19b E Mogilyansky, P Clark, K Quann, H Zhou, E Londin, Y Jing, I Rigoutsos Frontiers in Genetics 7, 210094, 2016 | 24 | 2016 |
The dichotomy between disease phenotype databases and the implications for understanding complex diseases involving the major histocompatibility complex PM Clark, M Kunkel, DS Monos International journal of immunogenetics 42 (6), 413-422, 2015 | 24 | 2015 |
Measuring complexity, nonextensivity and chaos in the DNA sequence of the Major Histocompatibility Complex GP Pavlos, LP Karakatsanis, AC Iliopoulos, EG Pavlos, MN Xenakis, ... Physica A: Statistical Mechanics and its Applications 438, 188-209, 2015 | 21 | 2015 |
A microfabricated quantum dot-linked immuno-diagnostic assay (μQLIDA) with an electrohydrodynamic mixing element C Yu, GB Kim, PM Clark, L Zubkov, ES Papazoglou, M Noh Sensors and Actuators B: Chemical 209, 722-728, 2015 | 17 | 2015 |
Computational assessment of miRNA binding to low and high expression HLA-DPB1 allelic sequences M Shieh, N Chitnis, P Clark, FB Johnson, M Kamoun, D Monos Human Immunology 80 (1), 53-61, 2019 | 13 | 2019 |