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Antibody-conjugated signaling nanocavities fabricated by dynamic molding for detecting cancers using small extracellular vesicle markers from tears T Takeuchi, K Mori, H Sunayama, E Takano, Y Kitayama, T Shimizu, ... Journal of the American Chemical Society 142 (14), 6617-6624, 2020 | 85 | 2020 |
Histone methylation status of H3K4me3 and H3K9me3 under methionine restriction is unstable in methionine-addicted cancer cells, but stable in normal cells J Yamamoto, Q Han, S Inubushi, N Sugisawa, K Hamada, H Nishino, ... Biochemical and biophysical research communications 533 (4), 1034-1038, 2020 | 74 | 2020 |
Oncogenic miRNAs identified in tear exosomes from metastatic breast cancer patients S Inubushi, H Kawaguchi, S Mizumoto, T Kunihisa, M Baba, Y Kitayama, ... Anticancer research 40 (6), 3091-3096, 2020 | 70 | 2020 |
Identification of annexin A1 as a novel substrate for E6AP‐mediated ubiquitylation T Shimoji, K Murakami, Y Sugiyama, M Matsuda, S Inubushi, J Nasu, ... Journal of cellular biochemistry 106 (6), 1123-1135, 2009 | 59 | 2009 |
Extent and instability of trimethylation of histone H3 lysine increases with degree of malignancy and methionine addiction J Yamamoto, Y Aoki, S Inubushi, Q Han, K Hamada, Y Tashiro, K Miyake, ... Cancer Genomics & Proteomics 19 (1), 12-18, 2022 | 43 | 2022 |
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy J Yamamoto, S Inubushi, Q Han, Y Tashiro, N Sugisawa, K Hamada, ... Iscience 25 (4), 2022 | 39 | 2022 |
Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model J Yamamoto, K Miyake, Q Han, Y Tan, S Inubushi, N Sugisawa, T Higuchi, ... Cancer Letters 492, 174-184, 2020 | 39 | 2020 |
MGDG extracted from spinach enhances the cytotoxicity of radiation in pancreatic cancer cells H Akasaka, Y Mizushina, K Yoshida, Y Ejima, N Mukumoto, T Wang, ... Radiation oncology 11, 1-11, 2016 | 37 | 2016 |
Hepatitis C virus NS5A protein interacts with and negatively regulates the non-receptor protein tyrosine kinase Syk S Inubushi, M Nagano-Fujii, K Kitayama, M Tanaka, C An, H Yokozaki, ... Journal of general virology 89 (5), 1231-1242, 2008 | 37 | 2008 |
Reversion of methionine addiction of osteosarcoma cells to methionine independence results in loss of malignancy, modulation of the epithelial-mesenchymal phenotype and … Y Aoki, Q Han, Y Tome, J Yamamoto, Y Kubota, N Masaki, K Obara, ... Frontiers in Oncology 12, 1009548, 2022 | 34 | 2022 |
Structural gene and strain specificity of a novel cysteine protease produced by Staphylococcus aureus isolated from a diseased chicken S Takeuchi, K Matsunaga, S Inubushi, H Higuchi, K Imaizumi, T Kaidoh Veterinary microbiology 89 (2-3), 201-210, 2002 | 33 | 2002 |
Linkage of methionine addiction, histone lysine hypermethylation, and malignancy. iScience 25 (4): 104162, 2022 J Yamamoto, S Inubushi, Q Han, Y Tashiro, N Sugisawa, K Hamada, ... DOI, 0 | 31 | |
Reversion from methionine addiction to methionine independence results in loss of tumorigenic potential of highly-malignant lung-cancer cells J Yamamoto, Y Aoki, Q Han, N Sugisawa, YU Sun, K Hamada, H Nishino, ... Anticancer Research 41 (2), 641-643, 2021 | 27 | 2021 |
Exosome-mediated radiosensitizing effect on neighboring cancer cells via increase in intracellular levels of reactive oxygen species A Nakaoka, M Nakahana, S Inubushi, H Akasaka, M Salah, Y Fujita, ... Oncology Reports 45 (4), 1-1, 2021 | 23 | 2021 |
Oral recombinant methioninase prevents obesity in mice on a high-fat diet Y Tashiro, Q Han, Y Tan, N Sugisawa, J Yamamoto, H Nishino, ... in vivo 34 (2), 489-494, 2020 | 21 | 2020 |
Triple-methyl blockade with recombinant methioninase, cycloleucine, and azacitidine arrests a pancreatic cancer patient-derived orthotopic xenograft model N Sugisawa, J Yamamoto, Q Han, Y Tan, Y Tashiro, H Nishino, ... Pancreas 50 (1), 93-98, 2021 | 20 | 2021 |
Over-methylation of histone H3 lysines is a common molecular change among the three major types of soft-tissue sarcoma in patient-derived xenograft (PDX) mouse models Y Aoki, J Yamamoto, Y Tome, K Hamada, N Masaki, S Inubushi, Y Tashiro, ... Cancer Genomics & Proteomics 18 (6), 715-721, 2021 | 19 | 2021 |
Investigation of the potential of using TiO2 nanoparticles as a contrast agent in computed tomography and magnetic resonance imaging H Akasaka, N Mukumoto, M Nakayama, T Wang, R Yada, Y Shimizu, ... Applied Nanoscience 10, 3143-3148, 2020 | 15 | 2020 |
Genetic and enzymatic analyses of metalloprotease (aureolysin) from Staphylococcus aureus isolated from domestic animals S Takeuchi, M Saito, K Imaizumi, T Kaidoh, H Higuchi, S Inubushi Veterinary microbiology 84 (1-2), 135-142, 2002 | 15 | 2002 |