Structural basis for histone H2B deubiquitination by the SAGA DUB module MT Morgan, M Haj-Yahya, AE Ringel, P Bandi, A Brik, C Wolberger Science 351 (6274), 725-728, 2016 | 248 | 2016 |
Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition A Maiti, MT Morgan, E Pozharski, AC Drohat Proceedings of the National Academy of Sciences 105 (26), 8890-8895, 2008 | 135 | 2008 |
Excision of 5-halogenated uracils by human thymine DNA glycosylase: Robust activity for DNA contexts other than CpG MT Morgan, MT Bennett, AC Drohat Journal of biological chemistry 282 (38), 27578-27586, 2007 | 117 | 2007 |
Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins M Jbara, S Laps, M Morgan, G Kamnesky, G Mann, C Wolberger, A Brik Nature communications 9 (1), 3154, 2018 | 90 | 2018 |
Role of two strictly conserved residues in nucleotide flipping and N-glycosylic bond cleavage by human thymine DNA glycosylase A Maiti, MT Morgan, AC Drohat Journal of biological chemistry 284 (52), 36680-36688, 2009 | 69 | 2009 |
Chemical synthesis of phosphorylated histone H2A at Tyr57 reveals insight into the inhibition mode of the SAGA deubiquitinating module M Jbara, SK Maity, M Morgan, C Wolberger, A Brik Angewandte Chemie International Edition 55 (16), 4972-4976, 2016 | 68 | 2016 |
Stoichiometry and affinity for thymine DNA glycosylase binding to specific and nonspecific DNA MT Morgan, A Maiti, ME Fitzgerald, AC Drohat Nucleic acids research 39 (6), 2319-2329, 2011 | 59 | 2011 |
Active site alanine mutations convert deubiquitinases into high‐affinity ubiquitin‐binding proteins ME Morrow, MT Morgan, M Clerici, K Growkova, M Yan, D Komander, ... EMBO reports 19 (10), e45680, 2018 | 54 | 2018 |
Solution structure of S100A1 bound to the CapZ peptide (TRTK12) NT Wright, BR Cannon, PT Wilder, MT Morgan, KM Varney, DB Zimmer, ... Journal of molecular biology 386 (5), 1265-1277, 2009 | 54 | 2009 |
Hydrazide mimics for protein lysine acylation to assess nucleosome dynamics and deubiquitinase action S Bhat, Y Hwang, MD Gibson, MT Morgan, SD Taverna, Y Zhao, ... Journal of the American Chemical Society 140 (30), 9478-9485, 2018 | 34 | 2018 |
FACT and Ubp10 collaborate to modulate H2B deubiquitination and nucleosome dynamics M Nune, MT Morgan, Z Connell, L McCullough, M Jbara, H Sun, A Brik, ... Elife 8, e40988, 2019 | 29 | 2019 |
Potent macrocycle inhibitors of the human SAGA deubiquitinating module M Morgan, T Ikenoue, H Suga, C Wolberger Cell chemical biology 29 (4), 544-554. e4, 2022 | 19 | 2022 |
Recognition of ubiquitinated nucleosomes MT Morgan, C Wolberger Current opinion in structural biology 42, 75-82, 2017 | 17 | 2017 |
Semisynthesis of ubiquitinated histone H2B with a native or nonhydrolyzable linkage M Morgan, M Jbara, A Brik, C Wolberger Methods in enzymology 618, 1-27, 2019 | 15 | 2019 |
Competition assay for measuring deubiquitinating enzyme substrate affinity MT Morgan, C Wolberger The Ubiquitin Proteasome System: Methods and Protocols, 59-70, 2018 | 2 | 2018 |