Nucleotide-binding oligomerization domain proteins are innate immune receptors for internalized Streptococcus pneumoniae B Opitz, A Püschel, B Schmeck, AC Hocke, S Rosseau, ... Journal of Biological Chemistry 279 (35), 36426-36432, 2004 | 437 | 2004 |
IFNβ induction by influenza A virus is mediated by RIG‐I which is regulated by the viral NS1 protein B Opitz, A Rejaibi, B Dauber, J Eckhard, M Vinzing, B Schmeck, ... Cellular microbiology 9 (4), 930-938, 2007 | 357 | 2007 |
Adrenomedullin reduces endothelial hyperpermeability S Hippenstiel, M Witzenrath, B Schmeck, A Hocke, M Krisp, M Krüll, ... Circulation research 91 (7), 618-625, 2002 | 243 | 2002 |
Listeria monocytogenes-infected human peripheral blood mononuclear cells produce IL-1β, depending on listeriolysin O and NLRP3 K Meixenberger, F Pache, J Eitel, B Schmeck, S Hippenstiel, H Slevogt, ... The Journal of Immunology 184 (2), 922-930, 2010 | 239 | 2010 |
Nod1-Mediated Endothelial Cell Activation by Chlamydophila pneumoniae B Opitz, S Förster, AC Hocke, M Maass, B Schmeck, S Hippenstiel, ... Circulation research 96 (3), 319-326, 2005 | 235 | 2005 |
Listeria monocytogenes activated p38 MAPK and induced IL-8 secretion in a nucleotide-binding oligomerization domain 1-dependent manner in endothelial cells B Opitz, A Puschel, W Beermann, AC Hocke, S Förster, B Schmeck, ... The Journal of Immunology 176 (1), 484-490, 2006 | 231 | 2006 |
Proteomic Characterization of the Whole Secretome of Legionella pneumophila and Functional Analysis of Outer Membrane Vesicles F Galka, SN Wai, H Kusch, S Engelmann, M Hecker, B Schmeck, ... Infection and immunity 76 (5), 1825-1836, 2008 | 221 | 2008 |
Lung epithelium as a sentinel and effector system in pneumonia–molecular mechanisms of pathogen recognition and signal transduction S Hippenstiel, B Opitz, B Schmeck, N Suttorp Respiratory research 7, 1-17, 2006 | 210 | 2006 |
Systemic use of the endolysin Cpl-1 rescues mice with fatal pneumococcal pneumonia M Witzenrath, B Schmeck, JM Doehn, T Tschernig, J Zahlten, JM Loeffler, ... Critical care medicine 37 (2), 642-649, 2009 | 189 | 2009 |
Legionella pneumophila induces IFNβ in lung epithelial cells via IPS-1 and IRF3, which also control bacterial replication B Opitz, M Vinzing, V van Laak, B Schmeck, G Heine, S Gunther, ... Journal of biological chemistry 281 (47), 36173-36179, 2006 | 169 | 2006 |
NAIP and Ipaf control Legionella pneumophila replication in human cells M Vinzing, J Eitel, J Lippmann, AC Hocke, J Zahlten, H Slevogt, ... The Journal of Immunology 180 (10), 6808-6815, 2008 | 162 | 2008 |
Role of pneumolysin for the development of acute lung injury in pneumococcal pneumonia M Witzenrath, B Gutbier, AC Hocke, B Schmeck, S Hippenstiel, K Berger, ... Critical care medicine 34 (7), 1947-1954, 2006 | 161 | 2006 |
Adrenomedullin reduces vascular hyperpermeability and improves survival in rat septic shock B Temmesfeld-Wollbrück, B Brell, I Dávid, M Dorenberg, J Adolphs, ... Intensive care medicine 33, 703-710, 2007 | 151 | 2007 |
Streptococcus pneumoniae-induced p38 MAPK-dependent phosphorylation of RelA at the interleukin-8 promotor B Schmeck, J Zahlten, K Moog, V Van Laak, S Huber, AC Hocke, B Opitz, ... Journal of Biological Chemistry 279 (51), 53241-53247, 2004 | 151 | 2004 |
Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells PD N'Guessan, F Riediger, K Vardarova, S Scharf, J Eitel, B Opitz, ... Arteriosclerosis, thrombosis, and vascular biology 29 (3), 380-386, 2009 | 150 | 2009 |
Rho protein inactivation induced apoptosis of cultured human endothelial cells S Hippenstiel, B Schmeck, PD N'Guessan, J Seybold, M Krull, K Preissner, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 283 (4 …, 2002 | 146 | 2002 |
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes H Limburg, A Harbig, D Bestle, DA Stein, HM Moulton, J Jaeger, H Janga, ... Journal of virology 93 (21), 10.1128/jvi. 00649-19, 2019 | 143 | 2019 |
Pneumococci induced TLR-and Rac1-dependent NF-κB-recruitment to the IL-8 promoter in lung epithelial cells B Schmeck, S Huber, K Moog, J Zahlten, AC Hocke, B Opitz, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (4 …, 2006 | 127 | 2006 |
Benefits of whole body vibration training in patients hospitalised for COPD exacerbations-a randomized clinical trial T Greulich, C Nell, J Koepke, J Fechtel, M Franke, B Schmeck, D Haid, ... BMC pulmonary medicine 14, 1-9, 2014 | 122 | 2014 |
Intracellular bacteria engage a STING–TBK1–MVB12b pathway to enable paracrine cGAS–STING signalling R Nandakumar, R Tschismarov, F Meissner, T Prabakaran, ... Nature microbiology 4 (4), 701-713, 2019 | 116 | 2019 |