| Two regulatory steps of ER-stress sensor Ire1 involving its cluster formation and interaction with unfolded proteins Y Kimata, Y Ishiwata-Kimata, T Ito, A Hirata, T Suzuki, D Oikawa, ... The Journal of cell biology 179 (1), 75-86, 2007 | 357 | 2007 |
| A role for BiP as an adjustor for the endoplasmic reticulum stress-sensing protein Ire1 Y Kimata, D Oikawa, Y Shimizu, Y Ishiwata-Kimata, K Kohno The Journal of cell biology 167 (3), 445-456, 2004 | 340 | 2004 |
| Activation of mammalian IRE1α upon ER stress depends on dissociation of BiP rather than on direct interaction with unfolded proteins D Oikawa, Y Kimata, K Kohno, T Iwawaki Experimental cell research 315 (15), 2496-2504, 2009 | 207 | 2009 |
| Identification of a consensus element recognized and cleaved by IRE1α D Oikawa, M Tokuda, A Hosoda, T Iwawaki Nucleic acids research 38 (18), 6265-6273, 2010 | 187 | 2010 |
| Identification of Toyocamycin, an agent cytotoxic for multiple myeloma cells, as a potent inhibitor of ER stress-induced XBP1 mRNA splicing M Ri, E Tashiro, D Oikawa, S Shinjo, M Tokuda, Y Yokouchi, T Narita, ... Blood cancer journal 2 (7), e79-e79, 2012 | 183 | 2012 |
| Self-association and BiP dissociation are not sufficient for activation of the ER stress sensor Ire1 D Oikawa, Y Kimata, K Kohno Journal of cell science 120 (9), 1681-1688, 2007 | 143 | 2007 |
| Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis S Nakazawa, D Oikawa, R Ishii, T Ayaki, H Takahashi, H Takeda, ... Nature communications 7 (1), 12547, 2016 | 135 | 2016 |
| Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 K Kato, H Nishimasu, D Oikawa, S Hirano, H Hirano, G Kasuya, R Ishitani, ... Nature communications 9 (1), 4424, 2018 | 129 | 2018 |
| Membrane lipid saturation activates IRE 1α without inducing clustering Y Kitai, H Ariyama, N Kono, D Oikawa, T Iwawaki, H Arai Genes to Cells 18 (9), 798-809, 2013 | 94 | 2013 |
| A transgenic mouse model for monitoring oxidative stress D Oikawa, R Akai, M Tokuda, T Iwawaki Scientific reports 2 (1), 229, 2012 | 90 | 2012 |
| Direct association of unfolded proteins with mammalian ER stress sensor, IRE1β D Oikawa, A Kitamura, M Kinjo, T Iwawaki PLoS One 7 (12), e51290, 2012 | 72 | 2012 |
| Site-specific cleavage of CD59 mRNA by endoplasmic reticulum-localized ribonuclease, IRE1 D Oikawa, M Tokuda, T Iwawaki Biochemical and biophysical research communications 360 (1), 122-127, 2007 | 54 | 2007 |
| Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide H Omura, D Oikawa, T Nakane, M Kato, R Ishii, R Ishitani, F Tokunaga, ... Scientific Reports 6 (1), 34756, 2016 | 51 | 2016 |
| Small-molecule inhibitors of linear ubiquitin chain assembly complex (LUBAC), HOIPINs, suppress NF-κB signaling K Katsuya, D Oikawa, K Iio, S Obika, Y Hori, T Urashima, K Ayukawa, ... Biochemical and biophysical research communications 509 (3), 700-706, 2019 | 49 | 2019 |
| An essential dimer-forming subregion of the endoplasmic reticulum stress sensor Ire1 D Oikawa, Y Kimata, M Takeuchi, K Kohno Biochemical Journal 391 (1), 135-142, 2005 | 49 | 2005 |
| Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses D Oikawa, Y Sato, F Ohtake, K Komakura, K Hanada, K Sugawara, ... Communications Biology 3 (1), 163, 2020 | 47 | 2020 |
| Linear ubiquitin code: its writer, erasers, decoders, inhibitors, and implications in disorders D Oikawa, Y Sato, H Ito, F Tokunaga International Journal of Molecular Sciences 21 (9), 3381, 2020 | 42 | 2020 |
| High-throughput screening for linear ubiquitin chain assembly complex (LUBAC) selective inhibitors using homogenous time-resolved fluorescence (HTRF)-based assay system K Katsuya, Y Hori, D Oikawa, T Yamamoto, K Umetani, T Urashima, ... SLAS DISCOVERY: Advancing Life Sciences R&D 23 (10), 1018-1029, 2018 | 36 | 2018 |
| The role of the unfolded protein response in diabetes mellitus T Iwawaki, D Oikawa Seminars in immunopathology 35, 333-350, 2013 | 36 | 2013 |
| Th2 cells and macrophages cooperatively induce allergic inflammation through histamine signaling N Iwasaki, S Terawaki, K Shimizu, D Oikawa, H Sakamoto, K Sunami, ... Plos one 16 (3), e0248158, 2021 | 31 | 2021 |
