Karsten Gronert
Karsten Gronert
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Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter proinflammation signals
CN Serhan, S Hong, K Gronert, SP Colgan, PR Devchand, G Mirick, ...
The Journal of experimental medicine 196 (8), 1025-1037, 2002
Lipid mediator class switching during acute inflammation: signals in resolution
BD Levy, CB Clish, B Schmidt, K Gronert, CN Serhan
Nature immunology 2 (7), 612-619, 2001
Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2–nonsteroidal antiinflammatory drugs and …
CN Serhan, CB Clish, J Brannon, SP Colgan, N Chiang, K Gronert
The Journal of experimental medicine 192 (8), 1197-1204, 2000
Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells: autacoids in anti-inflammation
S Hong, K Gronert, PR Devchand, RL Moussignac, CN Serhan
Journal of Biological Chemistry 278 (17), 14677-14687, 2003
Novel docosanoids inhibit brain ischemia-reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression
VL Marcheselli, S Hong, WJ Lukiw, XH Tian, K Gronert, A Musto, M Hardy, ...
Journal of Biological Chemistry 278 (44), 43807-43817, 2003
Obesity-induced insulin resistance and hepatic steatosis are alleviated by ω-3 fatty acids: a role for resolvins and protectins
A González-Périz, R Horrillo, N Ferre, K Gronert, B Dong, ...
The FASEB journal 23 (6), 1946, 2009
Rapid induction of inflammatory lipid mediators by the inflammasome in vivo
J von Moltke, NJ Trinidad, M Moayeri, AF Kintzer, SB Wang, ...
Nature 490 (7418), 107-111, 2012
A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense
K Gronert, N Maheshwari, N Khan, IR Hassan, M Dunn, ML Schwartzman
Journal of Biological Chemistry 280 (15), 15267-15278, 2005
NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of caspase-1 and-8
I Rauch, KA Deets, DX Ji, J von Moltke, JL Tenthorey, AY Lee, NH Philip, ...
Immunity 46 (4), 649-659, 2017
Activation of Lipoxin a4 Receptors by Aspirin-Triggered Lipoxins and Select Peptides Evokes Ligand-Specific Responses in Inflammation
N Chiang, IM Fierro, K Gronert, CN Serhan
The Journal of experimental medicine 191 (7), 1197-1208, 2000
Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues.
T Takano, CB Clish, K Gronert, N Petasis, CN Serhan
The Journal of clinical investigation 101 (4), 819-826, 1998
Docosahexaenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17S‐hydroxy‐DHA
A González‐Périz, A Planaguma, K Gronert, R Miquel, M López‐Parra, ...
The FASEB Journal 20 (14), 2537-2539, 2006
Leukotriene B4 receptor transgenic mice reveal novel protective roles for lipoxins and aspirin-triggered lipoxins in reperfusion
N Chiang, K Gronert, CB Clish, JA O’Brien, MW Freeman, CN Serhan
The Journal of clinical investigation 104 (3), 309-316, 1999
Local and systemic delivery of a stable aspirin-triggered lipoxin prevents neutrophil recruitment in vivo
CB Clish, JA O’Brien, K Gronert, GL Stahl, NA Petasis, CN Serhan
Proceedings of the National Academy of Sciences 96 (14), 8247-8252, 1999
5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ω-3 polyunsaturated fatty acids
P Sapieha, A Stahl, J Chen, MR Seaward, KL Willett, NM Krah, ...
Science translational medicine 3 (69), 69ra12-69ra12, 2011
Identification of a Human Enterocyte Lipoxin A4 Receptor That Is Regulated by Interleukin (IL)-13 and Interferon γ and Inhibits Tumor Necrosis Factor α–induced IL …
K Gronert, A Gewirtz, JL Madara, CN Serhan
The Journal of experimental medicine 187 (8), 1285-1294, 1998
The opportunistic pathogen Pseudomonas aeruginosa carries a secretable arachidonate 15-lipoxygenase
RE Vance, S Hong, K Gronert, CN Serhan, JJ Mekalanos
Proceedings of the National Academy of Sciences 101 (7), 2135-2139, 2004
Selectivity of recombinant human leukotriene D4, leukotriene B4, and lipoxin A4 receptors with aspirin-triggered 15-epi-LXA4 and regulation of vascular and inflammatory responses
K Gronert, T Martinsson-Niskanen, S Ravasi, N Chiang, CN Serhan
The American journal of pathology 158 (1), 3-9, 2001
Human ALX receptor regulates neutrophil recruitment in transgenic mice: roles in inflammation and host defense
PR Devchand, M Arita, S Hong, G Bannenberg, RL Moussignac, ...
The FASEB journal 17 (6), 652-659, 2003
Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics
M Sanak, BD Levy, CB Clish, N Chiang, K Gronert, L Mastalerz, ...
European Respiratory Journal 16 (1), 44-49, 2000
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