Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress–induced insulin resistance in cardiac cells in vitro and in vivo Y Tan, T Ichikawa, J Li, Q Si, H Yang, X Chen, CS Goldblatt, CJ Meyer, ... Diabetes 60 (2), 625-633, 2011 | 413 | 2011 |
Nitrated fatty acids: endogenous anti-inflammatory signaling mediators T Cui, FJ Schopfer, J Zhang, K Chen, T Ichikawa, RSB Paul, C Batthyany, ... Journal of Biological Chemistry 281 (47), 35686-35698, 2006 | 413 | 2006 |
Nrf2 protects against maladaptive cardiac responses to hemodynamic stress J Li, T Ichikawa, L Villacorta, JS Janicki, GL Brower, M Yamamoto, T Cui Arteriosclerosis, thrombosis, and vascular biology 29 (11), 1843-1850, 2009 | 276 | 2009 |
C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance H Sun, T Koike, T Ichikawa, K Hatakeyama, M Shiomi, B Zhang, ... The American journal of pathology 167 (4), 1139-1148, 2005 | 237 | 2005 |
Targeting the Nrf2 pathway against cardiovascular disease J Li, T Ichikawa, JS Janicki, T Cui Expert opinion on therapeutic targets 13 (7), 785-794, 2009 | 200 | 2009 |
Loss of NDRG2 expression activates PI3K-AKT signalling via PTEN phosphorylation in ATLL and other cancers S Nakahata, T Ichikawa, P Maneesaay, Y Saito, K Nagai, T Tamura, ... Nature communications 5 (1), 3393, 2014 | 168 | 2014 |
Electrophilic nitro-fatty acids inhibit vascular inflammation by disrupting LPS-dependent TLR4 signalling in lipid rafts L Villacorta, L Chang, SR Salvatore, T Ichikawa, J Zhang, ... Cardiovascular research 98 (1), 116-124, 2013 | 127 | 2013 |
Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes T Ichikawa, J Li, CJ Meyer, JS Janicki, M Hannink, T Cui PloS one 4 (12), e8391, 2009 | 117 | 2009 |
Lipoprotein (a) enhances advanced atherosclerosis and vascular calcification in WHHL transgenic rabbits expressing human apolipoprotein (a) H Sun, H Unoki, X Wang, J Liang, T Ichikawa, Y Arai, M Shiomi, ... Journal of Biological Chemistry 277 (49), 47486-47492, 2002 | 105 | 2002 |
Ubiquitin carboxyl-terminal hydrolase L1, a novel deubiquitinating enzyme in the vasculature, attenuates NF-κB activation Y Takami, H Nakagami, R Morishita, T Katsuya, TX Cui, T Ichikawa, ... Arteriosclerosis, thrombosis, and vascular biology 27 (10), 2184-2190, 2007 | 98 | 2007 |
Overexpression of human matrix metalloproteinase-12 enhances the development of inflammatory arthritis in transgenic rabbits X Wang, J Liang, T Koike, H Sun, T Ichikawa, S Kitajima, M Morimoto, ... The American journal of pathology 165 (4), 1375-1383, 2004 | 97 | 2004 |
An essential role of Nrf2 in American ginseng-mediated anti-oxidative actions in cardiomyocytes J Li, T Ichikawa, Y Jin, LJ Hofseth, P Nagarkatti, M Nagarkatti, A Windust, ... Journal of ethnopharmacology 130 (2), 222-230, 2010 | 95 | 2010 |
Overexpression of lipoprotein lipase in transgenic Watanabe heritable hyperlipidemic rabbits improves hyperlipidemia and obesity T Koike, J Liang, X Wang, T Ichikawa, M Shiomi, G Liu, H Sun, S Kitajima, ... Journal of Biological Chemistry 279 (9), 7521-7529, 2004 | 80 | 2004 |
Overexpression of the DNA sensor proteins, absent in melanoma 2 and interferon‐inducible 16, contributes to tumorigenesis of oral squamous cell carcinoma with p53 inactivation Y Kondo, K Nagai, S Nakahata, Y Saito, T Ichikawa, A Suekane, T Taki, ... Cancer Science 103 (4), 782-790, 2012 | 79 | 2012 |
Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits T Ichikawa, J Liang, S Kitajima, T Koike, X Wang, H Sun, M Morimoto, ... Atherosclerosis 179 (1), 87-95, 2005 | 79 | 2005 |
Nitroalkenes suppress lipopolysaccharide-induced signal transducer and activator of transcription signaling in macrophages: a critical role of mitogen-activated protein kinase … T Ichikawa, J Zhang, K Chen, Y Liu, FJ Schopfer, PRS Baker, BA Freeman, ... Endocrinology 149 (8), 4086-4094, 2008 | 73 | 2008 |
Lipoprotein (a) promotes smooth muscle cell proliferation and dedifferentiation in atherosclerotic lesions of human apo (a) transgenic rabbits T Ichikawa, H Unoki, H Sun, H Shimoyamada, S Marcovina, H Shikama, ... The American journal of pathology 160 (1), 227-236, 2002 | 71 | 2002 |
American ginseng preferentially suppresses STAT/iNOS signaling in activated macrophages T Ichikawa, J Li, P Nagarkatti, M Nagarkatti, LJ Hofseth, A Windust, T Cui Journal of ethnopharmacology 125 (1), 145-150, 2009 | 50 | 2009 |
Loss of NDRG2 expression confers oral squamous cell carcinoma with enhanced metastatic potential T Tamura, T Ichikawa, S Nakahata, Y Kondo, Y Tagawa, K Yamamoto, ... Cancer research 77 (9), 2363-2374, 2017 | 49 | 2017 |
Overexpression of lipoprotein lipase in transgenic rabbits leads to increased small dense LDL in plasma and promotes atherosclerosis T Ichikawa, S Kitajima, J Liang, T Koike, X Wang, H Sun, M Okazaki, ... Laboratory investigation 84 (6), 715-726, 2004 | 48 | 2004 |