フォロー
Zhixiang Pan
タイトル
引用先
引用先
Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide
Y Zheng, X Ji, B Yu, K Ji, D Gallo, E Csizmadia, M Zhu, MR Choudhury, ...
Nature chemistry 10 (7), 787-794, 2018
2312018
Click and release: bioorthogonal approaches to “on-demand” activation of prodrugs
X Ji, Z Pan, B Yu, LK De La Cruz, Y Zheng, B Ke, B Wang
Chemical Society Reviews 48 (4), 1077-1094, 2019
2292019
Esterase‐sensitive prodrugs with tunable release rates and direct generation of hydrogen sulfide
Y Zheng, B Yu, K Ji, Z Pan, V Chittavong, B Wang
Angewandte Chemie International Edition 55 (14), 4514-4518, 2016
1712016
Click and release: a chemical strategy toward developing gasotransmitter prodrugs by using an intramolecular Diels–Alder reaction
X Ji, C Zhou, K Ji, RE Aghoghovbia, Z Pan, V Chittavong, B Ke, B Wang
Angewandte Chemie International Edition 55 (51), 15846-15851, 2016
1382016
Organic CO‐prodrugs: Structure CO‐release rate relationship Studies
Z Pan, X Ji, V Chittavong, W Li, K Ji, M Zhu, J Zhang, B Wang
Chemistry-A European Journal, 2017
702017
pH-Sensitive metal-free carbon monoxide prodrugs with tunable and predictable release rates
X Ji, LKC De La Cruz, Z Pan, V Chittavong, B Wang
Chemical communications 53 (69), 9628-9631, 2017
702017
An esterase-activated click and release approach to metal-free CO-prodrugs
X Ji, K Ji, V Chittavong, B Yu, Z Pan, B Wang
Chemical communications 53 (59), 8296-8299, 2017
682017
Esterase-sensitive and pH-controlled carbon monoxide prodrugs for treating systemic inflammation
X Ji, Z Pan, C Li, T Kang, LKC De La Cruz, L Yang, Z Yuan, B Ke, B Wang
Journal of Medicinal Chemistry 62 (6), 3163-3168, 2019
602019
Click, release, and fluoresce: a chemical strategy for a cascade prodrug system for codelivery of carbon monoxide, a drug payload, and a fluorescent reporter
LKC De La Cruz, SL Benoit, Z Pan, B Yu, RJ Maier, X Ji, B Wang
Organic letters 20 (4), 897-900, 2018
532018
Organic CO prodrugs activated by endogenous ROS
Z Pan, J Zhang, K Ji, V Chittavong, X Ji, B Wang
Organic letters 20 (1), 8-11, 2018
522018
New coumarin derivatives: Design, synthesis and use as inhibitors of hMAO
X He, YY Chen, JB Shi, WJ Tang, ZX Pan, ZQ Dong, BA Song, J Li, XH Liu
Bioorganic & Medicinal Chemistry 22 (14), 3732-3738, 2014
452014
Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage
D Bakalarz, M Surmiak, X Yang, D Wójcik, E Korbut, Z Śliwowski, G Ginter, ...
Acta Pharmaceutica Sinica B 11 (2), 456-475, 2021
422021
Making smart drugs smarter: The importance of linker chemistry in targeted drug delivery
X Yang, Z Pan, MR Choudhury, Z Yuan, A Anifowose, B Yu, W Wang, ...
Medicinal research reviews 40 (6), 2682-2713, 2020
412020
Click and release: a high-content bioorthogonal prodrug with multiple outputs
X Ji, RE Aghoghovbia, LKC De La Cruz, Z Pan, X Yang, B Yu, B Wang
Organic letters 21 (10), 3649-3652, 2019
342019
New 2H-chromene-3-carboxamide derivatives: Design, synthesis and use as inhibitors of hMAO
ZX Pan, X He, YY Chen, WJ Tang, JB Shi, YL Tang, BA Song, J Li, XH Liu
European journal of medicinal chemistry 80, 278-284, 2014
312014
Towards “CO in a pill”: Pharmacokinetic studies of carbon monoxide prodrugs in mice
M Wang, X Yang, Z Pan, Y Wang, LK De La Cruz, B Wang, C Tan
Journal of controlled release 327, 174-185, 2020
302020
Discovery of a highly efficient nitroaryl group for detection of nitroreductase and imaging of hypoxic tumor cells
S Wang, X Wu, Y Zhang, D Zhang, B Xie, Z Pan, K Ouyang, T Peng
Organic & Biomolecular Chemistry 19 (15), 3469-3478, 2021
122021
Upregulation of p53 through induction of MDM2 degradation: amino acid prodrugs of anthraquinone analogs
A Anifowose, Z Yuan, X Yang, Z Pan, Y Zheng, Z Zhang, B Wang
Bioorganic & medicinal chemistry letters 30 (2), 126786, 2020
122020
Carbon-monoxide-releasing molecules and therapeutic applications thereof
B Wang, X Ji, PAN Zhixiang
US Patent 11,420,994, 2022
22022
A Stable Precursor for Bioorthogonally Removable 3-Isocyanopropyloxycarbonyl (ICPrc) Protecting Groups
J Tu, M Xu, RM Franzini
Synlett 31 (17), 1701-1706, 2020
12020
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