| Dual-sensitive nanomicelles enhancing systemic delivery of therapeutically active antibodies specifically into the brain J Xie, D Gonzalez-Carter, TA Tockary, N Nakamura, Y Xue, M Nakakido, ... ACS nano 14 (6), 6729-6742, 2020 | 67 | 2020 |
| Thermodynamics of antibody–antigen interaction revealed by mutation analysis of antibody variable regions H Akiba, K Tsumoto The journal of biochemistry 158 (1), 1-13, 2015 | 52 | 2015 |
| GPC1 specific CAR-T cells eradicate established solid tumor without adverse effects and synergize with anti-PD-1 Ab D Kato, T Yaguchi, T Iwata, Y Katoh, K Morii, K Tsubota, Y Takise, ... Elife 9, e49392, 2020 | 48 | 2020 |
| Structural and thermodynamic basis for the recognition of the substrate-binding cleft on hen egg lysozyme by a single-domain antibody H Akiba, H Tamura, M Kiyoshi, S Yanaka, K Sugase, JMM Caaveiro, ... Scientific reports 9 (1), 15481, 2019 | 42 | 2019 |
| Binuclear terbium (III) complex as a probe for tyrosine phosphorylation H Akiba, J Sumaoka, M Komiyama Chemistry–A European Journal 16 (17), 5018-5025, 2010 | 32 | 2010 |
| Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen K Yumura, H Akiba, S Nagatoishi, O Kusano-Arai, H Iwanari, T Hamakubo, ... The journal of biochemistry 162 (3), 203-210, 2017 | 30 | 2017 |
| Improved brain expression of anti-amyloid β scfv by complexation of mRNA including a secretion sequence with PEG-based block catiomer F Perche, S Uchida, H Akiba, CY Lin, M Ikegami, A Dirisala, T Nakashima, ... Current Alzheimer Research 14 (3), 295-302, 2017 | 29 | 2017 |
| Selective Detection of Phosphotyrosine in the Presence of Various Phosphate‐Containing Biomolecules with the Aid of a Terbium (III) Complex H Akiba, J Sumaoka, M Komiyama ChemBioChem 10 (11), 1773-1776, 2009 | 29 | 2009 |
| Click conjugation of a binuclear terbium (III) complex for real-time detection of tyrosine phosphorylation H Akiba, J Sumaoka, K Tsumoto, M Komiyama Analytical chemistry 87 (7), 3834-3840, 2015 | 26 | 2015 |
| Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody K Miyanabe, H Akiba, D Kuroda, M Nakakido, O Kusano-Arai, H Iwanari, ... The journal of biochemistry 164 (1), 65-76, 2018 | 16 | 2018 |
| Tyrosine sulfation restricts the conformational ensemble of a flexible peptide, strengthening the binding affinity for an antibody K Miyanabe, T Yamashita, Y Abe, H Akiba, Y Takamatsu, M Nakakido, ... Biochemistry 57 (28), 4177-4185, 2018 | 15 | 2018 |
| Selective sensing of tyrosine phosphorylation in peptides using Terbium (III) complexes J Sumaoka, H Akiba, M Komiyama International Journal of Analytical Chemistry 2016, 2016 | 15 | 2016 |
| Generation of biparatopic antibody through two-step targeting of fragment antibodies on antigen using SpyTag and SpyCatcher H Akiba, K Takayanagi, O Kusano-Arai, H Iwanari, T Hamakubo, ... Biotechnology reports 25, e00418, 2020 | 14 | 2020 |
| Conjugation-free, visual, and quantitative evaluation of inhibitors on protein tyrosine kinases and phosphatases with a luminescent Tb (III) complex H Akiba, J Sumaoka, T Hamakubo, M Komiyama Analytical and bioanalytical chemistry 406, 2957-2964, 2014 | 12 | 2014 |
| 111In-labeled anti-cadherin17 antibody D2101 has potential as a noninvasive imaging probe for diagnosing gastric cancer and lymph-node metastasis K Fujiwara, AB Tsuji, H Sudo, A Sugyo, H Akiba, H Iwanari, ... Annals of Nuclear Medicine 34, 13-23, 2020 | 10 | 2020 |
| Computer-guided library generation applied to the optimization of single-domain antibodies H Akiba, H Tamura, JMM Caaveiro, K Tsumoto Protein Engineering, Design and Selection 32 (9), 423-431, 2019 | 9 | 2019 |
| Roles of the disulfide bond between the variable and the constant domains of rabbit immunoglobulin kappa chains in thermal stability and affinity R Kawade, H Akiba, K Entzminger, T Maruyama, CJ Okumura, K Tsumoto Protein Engineering, Design and Selection 31 (7-8), 243-247, 2018 | 9 | 2018 |
| Synergistic cytotoxic effect on gastric cancer cells of an immunotoxin cocktail in which antibodies recognize different epitopes on CDH17 O Kusano-Arai, H Iwanari, S Kudo, C Kikuchi, A Yui, H Akiba, ... Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 37 (1), 1-11, 2018 | 9 | 2018 |
| Novel neutralizing human monoclonal antibodies against tetanus neurotoxin T Minamitani, K Kiyose, R Otsubo, T Ito, H Akiba, RA Furuta, T Inoue, ... Scientific Reports 11 (1), 12134, 2021 | 8 | 2021 |
| Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1 A Yui, H Akiba, S Kudo, M Nakakido, S Nagatoishi, K Tsumoto The journal of biochemistry 162 (4), 255-258, 2017 | 6 | 2017 |
