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Sofia B. Leite
Sofia B. Leite
European Commission - Join Research Centre (JRC); EURL-ECVAM
Verified email at ec.europa.eu
Title
Cited by
Cited by
Year
EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis
European Association for the Study of the Liver
Journal of hepatology 63 (1), 237-264, 2015
9512015
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
S Adler, D Basketter, S Creton, O Pelkonen, J Van Benthem, V Zuang, ...
Archives of toxicology 85, 367-485, 2011
6272011
The Hippo pathway effector YAP controls mouse hepatic stellate cell activation
I Mannaerts, SB Leite, S Verhulst, S Claerhout, N Eysackers, LFR Thoen, ...
Journal of hepatology 63 (3), 679-688, 2015
3422015
Human liver cell spheroids in extended perfusion bioreactor culture for repeated‐dose drug testing
RM Tostões, SB Leite, M Serra, J Jensen, P Björquist, MJT Carrondo, ...
Hepatology 55 (4), 1227-1236, 2012
2582012
Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro
SB Leite, T Roosens, A El Taghdouini, I Mannaerts, AJ Smout, M Najimi, ...
Biomaterials 78, 1-10, 2016
2292016
Generation of hepatic stellate cells from human pluripotent stem cells enables in vitro modeling of liver fibrosis
M Coll, L Perea, R Boon, SB Leite, J Vallverdú, I Mannaerts, A Smout, ...
Cell stem cell 23 (1), 101-113. e7, 2018
1992018
Toxicokinetics as a key to the integrated toxicity risk assessment based primarily on non-animal approaches
S Coecke, O Pelkonen, SB Leite, U Bernauer, JGM Bessems, FY Bois, ...
Toxicology in vitro 27 (5), 1570-1577, 2013
1572013
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA–EURL ECVAM ADME workshop
JG Bessems, G Loizou, K Krishnan, HJ Clewell III, C Bernasconi, F Bois, ...
Regulatory Toxicology and Pharmacology 68 (1), 119-139, 2014
1462014
Extending hepatocyte functionality for drug-testing applications using high-viscosity alginate–encapsulated three-dimensional cultures in bioreactors
JP Miranda, A Rodrigues, RM Tostoes, S Leite, H Zimmerman, ...
Tissue Engineering Part C: Methods 16 (6), 1223-1232, 2010
1212010
Three-dimensional HepaRG model as an attractive tool for toxicity testing
SB Leite, I Wilk-Zasadna, JM Zaldivar, E Airola, MA Reis-Fernandes, ...
Toxicological sciences 130 (1), 106-116, 2012
1122012
Perfusion of 3D encapsulated hepatocytes—A synergistic effect enhancing long‐term functionality in bioreactors
RM Tostões, SB Leite, JP Miranda, M Sousa, DIC Wang, MJT Carrondo, ...
Biotechnology and bioengineering 108 (1), 41-49, 2011
1052011
Towards an Extended Functional Hepatocyte In Vitro Culture
JP Miranda, SB Leite, U Muller-Vieira, A Rodrigues, MJT Carrondo, ...
Tissue Engineering Part C: Methods 15 (2), 157-167, 2009
1002009
Ab initio chemical safety assessment: A workflow based on exposure considerations and non-animal methods
E Berggren, A White, G Ouedraogo, A Paini, AN Richarz, FY Bois, T Exner, ...
Computational Toxicology 4, 31-44, 2017
812017
Merging bioreactor technology with 3D hepatocyte-fibroblast culturing approaches: Improved in vitro models for toxicological applications
SB Leite, AP Teixeira, JP Miranda, RM Tostões, JJ Clemente, MF Sousa, ...
Toxicology in Vitro 25 (4), 825-832, 2011
642011
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data
A Krebs, T Waldmann, MF Wilks, BMA van Vugt-Lussenburg, ...
ALTEX-Alternatives to animal experimentation 36 (4), 682-699, 2019
622019
Standardisation needs for organ on chip devices
M Piergiovanni, SB Leite, R Corvi, M Whelan
Lab on a Chip 21 (15), 2857-2868, 2021
592021
Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology
JA Harrill, MR Viant, CL Yauk, M Sachana, TW Gant, SS Auerbach, ...
Regulatory Toxicology and Pharmacology 125, 105020, 2021
512021
Stirred bioreactors for the expansion of adult pancreatic stem cells
M Serra, C Brito, SB Leite, E Gorjup, H von Briesen, MJT Carrondo, ...
Annals of Anatomy-Anatomischer Anzeiger 191 (1), 104-115, 2009
422009
Novel culture strategy for human stem cell proliferation and neuronal differentiation
M Serra, SB Leite, C Brito, J Costa, MJT Carrondo, PM Alves
Journal of neuroscience research 85 (16), 3557-3566, 2007
362007
Unfolded protein response is an early, non-critical event during hepatic stellate cell activation
I Mannaerts, LFR Thoen, N Eysackers, FJ Cubero, S Batista Leite, ...
Cell Death & Disease 10 (2), 98, 2019
302019
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